Training or Improvisation? Citizen journalists and their educational backgrounds-a comparative view

While citizen journalists hope to bring new impulses to mass media performance, it is often asked whether they are adequately trained for the production of “newsworthy” stories. This paper focuses on educational aspects of citizen journalism, which, to date, have largely been disregarded by empirical research. A comparative analytical design illustrates the different ways in which citizen journalists acquire and develop the skills that are necessary to undertake journalistic activities in the different journalism cultures throughout Europe. The authors carried out a multi-national analysis in six European countries (United Kingdom, Germany, Austria, Switzerland, Italy, and Poland). In each country, an extensive desk study helped to map the field of citizen journalism and highlight the most relevant examples. Semi-structured interviews with 54 practitioners in the field (representing different types of citizen journalism) made it possible to identify the alternative strategies that citizen journalists employ to prepare themselves for news production initiatives. The research demonstrates that the educational backgrounds of citizen journalists display differences as well as similarities—both within and across journalism cultures. While some of the actors in the field have a clear idea of what constitutes good journalism (and sometimes even aspire to work in a mainstream media organization), others seem to care little about journalistic standards and have only a vague idea about the identity of the profession. On the basis of these insights, the paper develops a typology of citizen journalists that takes into account both their education and their journalistic scope

Educational strategies in data journalism: A comparative study of six European countries

The article explores training programs in higher education with regard to data journalism from a multi-national perspective. By carrying out a comparative analysis in six European countries (Germany, Switzerland, the Netherlands, Italy, Poland, and the United Kingdom), it covers different models of media systems and journalistic cultures envisaged by Hallin and Mancini. Based on a desk review and in-depth interviews with instructors of data journalism in each country, the article identifies different approaches to the way data journalism is taught. In Europe, such programs are offered by four types of organizations: academic, vocational, professional, and civic. The role played by those organizations can be explained as a result of the peculiarities of national media systems. But there are also commonalities, for example, non-academic institutions (such as the European Journalism Center or the Center for Investigative Journalism) and major international news outlets (such as The Guardian and The New York Times) seem to take over a leading role in all of the analyzed countries. Generally speaking, data journalism education appears to be a very young discipline that frequently neglects fundamental journalistic topics such as ethical issues, transparency, accountability, and responsiveness although they are crucial in a journalistic field as sophisticated tools to reveal hidden aspects of reality

Google, Facebook and what else? Measuring the hybridity of Italian journalists by their use of sources

The contemporary media systems present hybrid logics and features that imply an increasingly interdependence among actors, media and communication formats. The hybrid media system approach underlines that legacy news media and non-elite media actors construct flows of news through different media technologies and according to complex temporal structures. A media environment arises in which traditional distinctions between concepts like \u2018online\u2019 and \u2018offline\u2019, \u2018producer\u2019 and \u2018audience\u2019, \u2018citizens\u2019 and \u2018journalists\u2019 become blurred. The emphasis appears to be on change more than continuity, and on difference more than similarity. Although the hybrid media approach is appreciated by numerous contemporary media scholars, hybridity in media often remains an all-encompassing concept and few attempts have been made to measure it. This article assesses the level of hybridity by investigating journalists\u2019 uses of sources. It considers mainly journalists\u2019 use of sources by the medium for which they work (from newspapers to web or radio) and the kinds of news that they produce (hard or soft news, business/finance, tech/science). The contemporary media systems present hybrid logics and features that imply an increasingly interdependence among actors, media and communication formats. The hybrid media system approach underlines that legacy news media and non-elite media actors construct flows of news through different media technologies and according to complex temporal structures. A media environment arises in which traditional distinctions between concepts like \u2018online\u2019 and \u2018offline\u2019, \u2018producer\u2019 and \u2018audience\u2019, \u2018citizens\u2019 and \u2018journalists\u2019 become blurred. The emphasis appears to be on change more than continuity, and on difference more than similarity. Although the hybrid media approach is appreciated by numerous contemporary media scholars, hybridity in media often remains an all-encompassing concept and few attempts have been made to measure it. This article assesses the level of hybridity by investigating journalists\u2019 uses of sources. It considers mainly journalists\u2019 use of sources by the medium for which they work (from newspapers to web or radio) and the kinds of news that they produce (hard or soft news, business/finance, tech/science). The assumption is, therefore, that, within a homogeneously hybridized media system, journalists use the same sources regardless of the medium for which they work and the topics with which they deal. This objective is pursued by analysing the data collected via a survey conducted by means of structured interviews with a sample of 1424 Italian journalists between October and November 2016. The findings show that the analytical distinction among platforms for which journalists work still matters in terms of sources. Except for the use of Facebook and Google, journalists have still very defined paths to collect sources according to the medium they work for. The article has implications also for the literature on journalists\u2019 authority and expertis

Liquid Foam-Ethyl Vinyl Acetate Adhesive Systems for Lining Process of Paintings: Prospects of a User-Friendly, Harmless Alternative to Conventional Products

The lining of paintings is a process of conservation science and art restoration used to strengthen, flatten, or consolidate paintings on canvas by attaching by means of adhesives a second canvas to the back of the existing one. To this aim, the prospects of the use of ethyl vinyl acetate (EVA) resins in aqueous dispersion applied as an adhesive in a foam form have been investigated in the present study. The key physical properties of the foam have been investigated, with a deep focus on rheological behavior and the drying rate, comparing the results with those obtained using the liquid products that are commercially available. Dedicated mock-ups have been prepared to test the adhesive for the lining process, inspecting adhesion strength, colorimetric properties, and the influence on the possible chromatic and visual alteration of the surface, also looking at the chemical interaction with painting materials and the deterioration after an artificial ageing process. The results obtained clearly indicated that the proposed technology is very suitable for the targeted application, and an EVA water-based foamed dispersion can be used for paintings' lining, in view of the ease of application, being an appropriate adhesion, no chemical interaction, nor the deterioration of the painting

Reduced transcription of TCOF1 in adult cells of Treacher Collins syndrome patients

<p>Abstract</p> <p>Background</p> <p>Treacher Collins syndrome (TCS) is an autosomal dominant craniofacial disorder caused by frameshift deletions or duplications in the <it>TCOF1 </it>gene. These mutations cause premature termination codons, which are predicted to lead to mRNA degradation by nonsense mediated mRNA decay (NMD). Haploinsufficiency of the gene product (treacle) during embryonic development is the proposed molecular mechanism underlying TCS. However, it is still unknown if <it>TCOF1 </it>expression levels are decreased in post-embryonic human cells.</p> <p>Methods</p> <p>We have estimated <it>TCOF1 </it>transcript levels through real time PCR in mRNA obtained from leucocytes and mesenchymal cells of TCS patients (n = 23) and controls (n = 18). Mutational screening and analysis of NMD were performed by direct sequencing of gDNA and cDNA, respectively.</p> <p>Results</p> <p>All the 23 patients had typical clinical features of the syndrome and pathogenic mutations were detected in 19 of them. We demonstrated that the expression level of <it>TCOF1 </it>is 18-31% lower in patients than in controls (<it>p < 0.05</it>), even if we exclude the patients in whom we did not detect the pathogenic mutation. We also observed that the mutant allele is usually less abundant than the wild type one in mesenchymal cells.</p> <p>Conclusions</p> <p>This is the first study to report decreased expression levels of <it>TCOF1 </it>in TCS adult human cells, but it is still unknown if this finding is associated to any phenotype in adulthood. In addition, as we demonstrated that alleles harboring the pathogenic mutations have lower expression, we herein corroborate the current hypothesis of NMD of the mutant transcript as the explanation for diminished levels of <it>TCOF1 </it>expression. Further, considering that <it>TCOF1 </it>deficiency in adult cells could be associated to pathologic clinical findings, it will be important to verify if TCS patients have an impairment in adult stem cell properties, as this can reduce the efficiency of plastic surgery results during rehabilitation of these patients.</p

The history of leishmaniasis

In this review article the history of leishmaniasis is discussed regarding the origin of the genus Leishmania in the Mesozoic era and its subsequent geographical distribution, initial evidence of the disease in ancient times, first accounts of the infection in the Middle Ages, and the discovery of Leishmania parasites as causative agents of leishmaniasis in modern times. With respect to the origin and dispersal of Leishmania parasites, the three currently debated hypotheses (Palaearctic, Neotropical and supercontinental origin, respectively) are presented. Ancient documents and paleoparasitological data indicate that leishmaniasis was already widespread in antiquity. Identification of Leishmania parasites as etiological agents and sand flies as the transmission vectors of leishmaniasis started at the beginning of the 20th century and the discovery of new Leishmania and sand fly species continued well into the 21st century. Lately, the Syrian civil war and refugee crises have shown that leishmaniasis epidemics can happen any time in conflict areas and neighbouring regions where the disease was previously endemic

Fishing the Molecular Bases of Treacher Collins Syndrome

Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development, and mutations in the TCOF1 gene are responsible for over 90% of TCS cases. The knowledge about the molecular mechanisms responsible for this syndrome is relatively scant, probably due to the difficulty of reproducing the pathology in experimental animals. Zebrafish is an emerging model for human disease studies, and we therefore assessed it as a model for studying TCS. We identified in silico the putative zebrafish TCOF1 ortholog and cloned the corresponding cDNA. The derived polypeptide shares the main structural domains found in mammals and amphibians. Tcof1 expression is restricted to the anterior-most regions of zebrafish developing embryos, similar to what happens in mouse embryos. Tcof1 loss-of-function resulted in fish showing phenotypes similar to those observed in TCS patients, and enabled a further characterization of the mechanisms underlying craniofacial malformation. Besides, we initiated the identification of potential molecular targets of treacle in zebrafish. We found that Tcof1 loss-of-function led to a decrease in the expression of cellular proliferation and craniofacial development. Together, results presented here strongly suggest that it is possible to achieve fish with TCS-like phenotype by knocking down the expression of the TCOF1 ortholog in zebrafish. This experimental condition may facilitate the study of the disease etiology during embryonic development

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice

The neurodevelopmental disorder Williams-Beuren syndrome is caused by spontaneous similar to 1.5 Mb deletions comprising 25 genes on human chromosome 7q11.23. To functionally dissect the deletion and identify dosage-sensitive genes, we created two half-deletions of the conserved syntenic region on mouse chromosome 5G2. Proximal deletion (PD) mice lack Gtf2i to Limk1, distal deletion (DD) mice lack Limk1 to Fkbp6, and the double heterozygotes (D/P) model the complete human deletion. Gene transcript levels in brain are generally consistent with gene dosage. Increased sociability and acoustic startle response are associated with PD, and cognitive defects with DD. Both PD and D/P males are growth-retarded, while skulls are shortened and brains are smaller in DD and D/P. Lateral ventricle (LV) volumes are reduced, and neuronal cell density in the somatosensory cortex is increased, in PD and D/P. Motor skills are most impaired in D/P. Together, these partial deletion mice replicate crucial aspects of the human disorder and serve to identify genes and gene networks contributing to the neural substrates of complex behaviours and behavioural disorders

Genome Analysis of the Domestic Dog (Korean Jindo) by Massively Parallel Sequencing

Although pioneering sequencing projects have shed light on the boxer and poodle genomes, a number of challenges need to be met before the sequencing and annotation of the dog genome can be considered complete. Here, we present the DNA sequence of the Jindo dog genome, sequenced to 45-fold average coverage using Illumina massively parallel sequencing technology. A comparison of the sequence to the reference boxer genome led to the identification of 4 675 437 single nucleotide polymorphisms (SNPs, including 3 346 058 novel SNPs), 71 642 indels and 8131 structural variations. Of these, 339 non-synonymous SNPs and 3 indels are located within coding sequences (CDS). In particular, 3 non-synonymous SNPs and a 26-bp deletion occur in the TCOF1 locus, implying that the difference observed in cranial facial morphology between Jindo and boxer dogs might be influenced by those variations. Through the annotation of the Jindo olfactory receptor gene family, we found 2 unique olfactory receptor genes and 236 olfactory receptor genes harbouring non-synonymous homozygous SNPs that are likely to affect smelling capability. In addition, we determined the DNA sequence of the Jindo dog mitochondrial genome and identified Jindo dog-specific mtDNA genotypes. This Jindo genome data upgrade our understanding of dog genomic architecture and will be a very valuable resource for investigating not only dog genetics and genomics but also human and dog disease genetics and comparative genomics