GM crops and gender issues

Correspondence in the December issue by Jonathan Gressel not only states that gender issues in rural settings have not been adequately addressed with respect to weed control biotech but also asserts that such technology can increase the quality of life of rural women in developing countries. Improved weed control is a labor-saving technology that can result in less employment in a labor surplus rural economy. Often in rural areas, wage income is the main source of income and an important determinant of the quality of life, particularly where employment opportunities are generally limited. Apart from soil preparation, planting and weeding, harvesting is also 'femanual' work that can generate more employment if yields are higher. Biotech can enhance the quality of life of women but only if the technology is associated with overall generation of rural employment

The structure of dark matter halos in hierarchical clustering theories

During hierarchical clustering, smaller masses generally collapse earlier than larger masses and so are denser on the average. The core of a small mass halo could be dense enough to resist disruption and survive undigested, when it is incorporated into a bigger object. We explore the possibility that a nested sequence of undigested cores in the center of the halo, which have survived the hierarchical, inhomogeneous collapse to form larger and larger objects, determines the halo structure in the inner regions. For a flat universe with $P(k) \propto k^n$, scaling arguments then suggest that the core density profile is, $\rho \propto r^{-\alpha}$ with $\alpha = (9+3n)/(5+n)$. But whether such behaviour obtains depends on detailed dynamics. We first examine the dynamics using a fluid approach to the self-similar collapse solutions for the dark matter phase space density, including the effect of velocity dispersions. We highlight the importance of tangential velocity dispersions to obtain density profiles shallower than $1/r^2$ in the core regions. If tangential velocity dispersions in the core are constrained to be less than the radial dispersion, a cuspy core density profile shallower than 1/r cannot obtain, in self-similar collapse. We then briefly look at the profiles of the outer halos in low density cosmological models where the total halo mass is convergent. Finally, we analyze a suite of dark halo density and velocity dispersion profiles obtained in cosmological N-body simulations of models with n= 0, -1 and -2. We find that the core-density profiles of dark halos, show considerable scatter in their properties, but nevertheless do appear to reflect a memory of the initial power spectrum, with steeper initial spectra producing flatter core profiles. (Abridged)Comment: 31 pages, 7 figures, submitted to Ap

Stochastic dynamics of active swimmers in linear flows

Most classical work on the hydrodynamics of low-Reynolds-number swimming addresses deterministic locomotion in quiescent environments. Thermal fluctuations in fluids are known to lead to a Brownian loss of the swimming direction. As most cells or synthetic swimmers are immersed in external flows, we consider theoretically in this paper the stochastic dynamics of a model active particle (a self-propelled sphere) in a steady general linear flow. The stochasticity arises both from translational diffusion in physical space, and from a combination of rotary diffusion and run-and-tumble dynamics in orientation space. We begin by deriving a general formulation for all components of the long-time mean square displacement tensor for a swimmer with a time-dependent swimming velocity and whose orientation decorrelates due to rotary diffusion alone. This general framework is applied to obtain the convectively enhanced mean-squared displacements of a steadily-swimming particle in three canonical linear flows (extension, simple shear, and solid-body rotation). We then show how to extend our results to the case where the swimmer orientation also decorrelates on account of run-and-tumble dynamics. Self-propulsion in general leads to the same long-time temporal scalings as for passive particles in linear flows but with increased coefficients. In the particular case of solid-body rotation, the effective long-time diffusion is the same as that in a quiescent fluid, and we clarify the lack of flow-dependence by briefly examining the dynamics in elliptic linear flows. By comparing the new active terms with those obtained for passive particles we see that swimming can lead to an enhancement of the mean-square displacements by orders of magnitude, and could be relevant for biological organisms or synthetic swimming devices in fluctuating environmental or biological flows

Dielectric and polarization experiments in high loss dielectrics: a word of caution

The recent quest for improved functional materials like high permittivity dielectrics and/or multiferroics has triggered an intense wave of research. Many materials have been checked for their dielectric permittivity or their polarization state. In this report, we call for caution when samples are simultaneously displaying insulating behavior and defect-related conductivity. Many oxides containing mixed valent cations or oxygen vacancies fall in this category. In such cases, most of standard experiments may result in effective high dielectric permittivity which cannot be related to ferroelectric polarization. Here we list few examples of possible discrepancies between measured parameters and their expected microscopic origin

Non-collinear Magnetic Order in the Double Perovskites: Double Exchange on a Geometrically Frustrated Lattice

Double perovskites of the form A_2BB'O_6 usually involve a transition metal ion, B, with a large magnetic moment, and a non magnetic ion B'. While many double perovskites are ferromagnetic, studies on the underlying model reveal the possibility of antiferromagnetic phases as well driven by electron delocalisation. In this paper we present a comprehensive study of the magnetic ground state and T_c scales of the minimal double perovskite model in three dimensions using a combination of spin-fermion Monte Carlo and variational calculations. In contrast to two dimensions, where the effective magnetic lattice is bipartite, three dimensions involves a geometrically frustrated face centered cubic (FCC) lattice. This promotes non-collinear spiral states and `flux' like phases in addition to collinear anti-ferromagnetic order. We map out the possible magnetic phases for varying electron density, `level separation' epsilon_B - epsilon_B', and the crucial B'-B' (next neighbour) hopping t'.Comment: 15 pages pdflatex + 19 figs, revision: removed redundant comment

Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism.

Colonocytes possess a specific carrier-mediated uptake process for the microbiota-generated thiamin (vitamin B1) pyrophosphate (TPP) that involves the TPP transporter (TPPT; product of the SLC44A4 gene). Little is known about the effect of exogenous factors (including enteric pathogens) on the colonic TPP uptake process. Our aim in this study was to investigate the effect of Enterohemorrhagic Escherichia coli (EHEC) infection on colonic uptake of TPP. We used human-derived colonic epithelial NCM460 cells and mice in our investigation. The results showed that infecting NCM460 cells with live EHEC (but not with heat-killed EHEC, EHEC culture supernatant, or with non-pathogenic E. Coli) to lead to a significant inhibition in carrier-mediated TPP uptake, as well as in level of expression of the TPPT protein and mRNA. Similarly, infecting mice with EHEC led to a significant inhibition in colonic TPP uptake and in level of expression of TPPT protein and mRNA. The inhibitory effect of EHEC on TPP uptake by NCM460 was found to be associated with reduction in the rate of transcription of the SLC44A4 gene as indicated by the significant reduction in the activity of the SLC44A4 promoter transfected into EHEC infected cells. The latter was also associated with a marked reduction in the level of expression of the transcription factors CREB-1 and ELF3, which are known to drive the activity of the SLC44A4 promoter. Finally, blocking the ERK1/2 and NF-kB signaling pathways in NCM460 cells significantly reversed the level of EHEC inhibition in TPP uptake and TPPT expression. Collectively, these findings show, for the first time, that EHEC infection significantly inhibit colonic uptake of TPP, and that this effect appears to be exerted at the level of SLC44A4 transcription and involves the ERK1/2 and NF-kB signaling pathways