Nucleoside, nucleotide and oligonucleotide based amphiphiles : a successful mariage of nucleic acids with lipids

Amphiphilic molecules based on nucleosides, nucleotides and oligonucleotides are finding more and more biotechnological applications. This Perspective highlights their synthesis, supramolecular organization as well as their applications in the field of biotechnology

A versatile reagent to synthesize diverse ionic liquids ranging from small molecules and dendrimers to functionalized proteins

An ionic liquid “reagent” bearing a succinimidyl activated ester is reported that can be used to synthesize a variety of small molecule and macromolecular ionic liquids. In addition, the ionic liquid reagent was used to modify lysozyme, and the protein retained its structure and function after modification. This study describes a facile and reliable route to new ionic liquid compositions

Novel iron-specific fluorescent probes

A series of novel iron-specific fluorescent probes is reported where the chelator function unusually forms part of the fluorescent moiety. The ability of this range of molecules to permeate human erythrocyte ghost membranes was investigated. (c) 2005 Elsevier Ltd. All rights reserve