121 research outputs found

    Automatic generation of scheduling and communication code in real-time parallel programs

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    Inter-process communication and scheduling are notorious problem areas in the design of real-time systems. Using CASE tools, the system design phase will in general result in a system description in the form of parallel processes. Manual allocation of these processes to processors may result in error prone and/or slow communication code. Scheduling of the processes, necessary to meet timing constraints, is also a tedious task that takes many iterations. The described design tools result in code that is comparable in quality and performance with expert manual realization. Many network layers have been implemented to relieve the user from the low-level programming of communication software. However, the increase in user-friendliness is usually paid with performance degradation. The proposed approach combines user-friendliness with high performance by generating communication software that is tailor-made for the application. A similar approach is followed with the scheduling software. Schedulers in the form of a built-in a kernel are available all the time and cause overhead all the time. The proposed preprocessor tool generates scheduling software after analyzing the timing requirements of the particular application. This results in simple code for simple timing requirements and more complicated code for complex timing requirements. The tools have been implemented in Occam for use on a transputer. However, the results are valid for any distributed memory machine

    Where are the Geographers? Newly Incorporated Municipalities (NIMs) in the South

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    The creation of new cities can have dramatic impacts on urban landscapes regarding tax rates, land use patterns, school districts, and the provision of other municipal services. Between 1990 and 2005, 193 newly incorporated municipalities (NIMs) were created in the South. The study of these new cities falls under the purview of the larger field of boundary change. Boundary change can take the form of annexation, consolidation/ merger, secession, the formation of special districts, and incorporation. This paper examines the current literature on the different forms of boundary change and provides potential explanations for why municipal incorporation is an area of research that has been overlooked by geographers. Through a case study of municipal incorporation in the South, this paper will then explore the ways in which geographers can contribute to our understanding of this topic

    Mixed origin of neovascularization of human endometrial grafts in immunodeficient mouse models

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    peer reviewedBACKGROUND: In vivo mouse models have been developed to study the physiology of normal and pathologic endometrium. Although angiogenesis is known to play an important role in endometrial physiology and pathology, the origin of neovasculature in xenografts remains controversial. The aim of this study was to assess the origin of the neovasculature of endometrial grafts in different mouse models. METHODS: Human proliferative endometrium (n = 19 women) was grafted s.c. in two immunodeficient mouse strains: nude (n = 8) and severely compromised immunodeficient (SCID; n = 20). Mice were also treated with estradiol, progesterone or levonorgestrel. Fluorescence in-situ hybridization using a centromeric human chromosome X probe, immunohistochemistry (von Willebrand factor and collagen IV) and lectin perfusion were performed to identify the origin of the vessels. RESULTS: More than 90% of vessels within xenografts were of human origin 4 weeks after implantation. Some vessels (9.67 +/- 2.01%) were successively stained by human or mouse specific markers, suggesting the presence of chimeric vessels exhibiting a succession of human and murine portions. No difference in staining was observed between the two strains of mouse or different hormone treatments. Furthermore, erythrocytes were found inside human vessels, confirming their functionality. CONCLUSION: This article shows that human endometrial grafts retain their own vessels, which connect to the murine vasculature coming from the host tissue and become functional

    Leveraging the Future Foothills: Asset Mapping the North Carolina Furniture Industry Cluster

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    North Carolina features the second largest furniture industry by state in the nation, despite a decline in the state’s furniture manufacturing jobs by more than 50% from 2001to 2009 . Previous studies of the North Carolina furniture industry suggested that the state should not give up on this traditional manufacturing strength but instead figure out how to best adapt to new economic realities. A contributing weakness is the tendency of major furniture regions in the state to operate in isolation from each other even though leveraging the various furniture industry clusters can help facilitate a statewide comparative advantage

    Study of Visitors to North Carolina Wineries

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    The wine and grape industry generates a significant economic impact in North Carolina’s rural communities. In 2009 the wine and grape industry generated 7,600 jobs and 1.2billionintotalannualeconomicimpactinthestate.ParticularlynoteworthyisthefactthatNCswinetourismrevenuegrew271.2 billion in total annual economic impact in the state. Particularly noteworthy is the fact that NC’s wine tourism revenue grew 27% between 2005 and 2009, with 2009 data indicating 1.26 million wine tourist visits and 156 million in wine tourism revenue

    Facile Synthesis of Amine-Functionalized Eu3+-Doped La(OH)3 Nanophosphors for Bioimaging

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    Here, we report a straightforward synthesis process to produce colloidal Eu3+-activated nanophosphors (NPs) for use as bioimaging probes. In this procedure, poly(ethylene glycol) serves as a high-boiling point solvent allowing for nanoscale particle formation as well as a convenient medium for solvent exchange and subsequent surface modification. The La(OH)3:Eu3+ NPs produced by this process were ~3.5 nm in diameter as determined by transmission electron microscopy. The NP surface was coated with aminopropyltriethoxysilane to provide chemical functionality for attachment of biological ligands, improve chemical stability and prevent surface quenching of luminescent centers. Photoluminescence spectroscopy of the NPs displayed emission peaks at 597 and 615 nm (λex = 280 nm). The red emission, due to 5D0 → 7F1 and 5D0 → 7F2 transitions, was linear with concentration as observed by imaging with a conventional bioimaging system. To demonstrate the feasibility of these NPs to serve as optical probes in biological applications, an in vitro experiment was performed with HeLa cells. NP emission was observed in the cells by fluorescence microscopy. In addition, the NPs displayed no cytotoxicity over the course of a 48-h MTT cell viability assay. These results suggest that La(OH)3:Eu3+ NPs possess the potential to serve as a luminescent bioimaging probe

    Real-time imaging using a 4.3-THz quantum cascade laser and a 320×240 microbolometer focal-plane array

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    Abstract: We report on the development of a compact, easy-to-use terahertz radiation source, which combines a quantum-cascade laser (QCL) operating at 3.1 THz with a compact, low-input-power Stirling cooler. The QCL, which is based on a two-miniband design, has been developed for high output and low electrical pump power. The amount of generated heat complies with the nominal cooling capacity of the Stirling cooler of 7 W at 65 K with 240 W of electrical input power. Special care has been taken to achieve a good thermal coupling between the QCL and the cold finger of the cooler. The whole system weighs less than 15 kg including the cooler and power supplies. The maximum output power is 8 mW at 3.1 THz. With an appropriate optical beam shaping, the emission profile of the laser is fundamental Gaussian. The applicability of the system is demonstrated by imaging and molecular-spectroscopy experiments. Hübers, "Sub-megahertz frequency stabilization of a terahertz quantum cascade laser to a molecular absorption line," Appl. Phys. Lett. 96(7), 071112 (2010). ©2010 Optical Society of Americ

    Parallel and Distributed Computing in Education (Invited Talk)

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    The natural world is certainly not organised through a central thread of control. Things happen as the result of the actions and interactions of unimaginably large numbers of independent agents, operating at all levels of scale from nuclear to astronomic. Computer systems aiming to be of real use in this real world need to model, at the appropriate level of abstraction, that part of it for which it is to be of service. If that modelling can reflect the natural concurrency in the system, it ought to be much simpler Yet, traditionally, concurrent programming is considered to be an advanced and difficult topic - certainly much harder than serial computing which, therefore, needs to be mastered first. But this tradition is wrong. This talk presents an intuitive, sound and practical model of parallel computing that can be mastered by undergraduate students in the first year of a computing (major) degree. It is based upon Hoare's mathematical theory of Communicating Sequential Processes (CSP), but does not require mathematical maturity from the students - that maturity is pre-engineered in the model. Fluency can be quickly developed in both message-passing and shared-memory concurrency, whilst learning to cope with key issues such as race hazards, deadlock, livelock, process starvation and the efficient use of resources. Practical work can be hosted on commodity PCs or UNIX workstations using either Java or the Occam multiprocessing language. Armed with this maturity, students are well-prepared for coping with real problems on real parallel architectures that have, possibly, less robust mathematical foundations
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