On the motion of a classical charged particle

We show that the Lorentz-Dirac equation is not an unavoidable consequence of energy-momentum conservation for a point charge. What follows solely from conservation laws is a less restrictive equation already obtained by Honig and Szamosi. The latter is not properly an equation of motion because, as it contains an extra scalar variable, it does not determine the future evolution of the charge. We show that a supplementary constitutive relation can be added so that the motion is determined and free from the troubles that are customary in Lorentz-Dirac equation, i. e. preacceleration and runaways

Design of a Compressor Load Stand Capable of Supplying Two-Phase Refrigerant at Two Intermediate Pressures

The development of compressors with refrigerant injection ports provides a less complex and less costly alternative to implementing multi-stage compressors with economization. The ports can be used to inject economized refrigerant during the compression process, which provides the desired cooling effect and decreases the work required to compress the gas per unit mass. Experiments have shown that injecting liquid or low quality refrigerant is effective for reducing the compressor exit temperature and improving system reliability, while injecting refrigerant vapor improves the cooling or heating capacity of the system. However, very little information is available for cycles operating with injection states between these limits of liquid and vapor injection. Theoretical work suggests that cycle performance with two-phase refrigerant injection can provide greater improvements in COP than vapor injection. In addition, experimental work has shown that increasing the number of stages in an economized cycle with a multi-stage compressor improves the cycle performance, and theoretical work suggests that increasing the number of injection ports would have a similar effect. Therefore, this paper presents the design of a compressor load stand for testing compressors with multiple injection ports. The load stand is based on a traditional hot gas bypass configuration but is capable of supplying refrigerant to injection ports at two different pressures between the compressor suction and discharge pressures. In addition, the state of the injected refrigerant can be controlled such that it is either superheated vapor or a saturated liquid-vapor mixture. To guide the design of the bench and size system components, a model was developed to predict the system performance with a commercially available R-410A compressor that has a single injection port. The model is used to predict the range of injection conditions that can be achieved with the load stand over a range of operating conditions. Finally, preliminary test results for the load stand operating without injection are presented, and the experimentally measured compressor performance is compared to the performance data published by the compressor manufacturer

Modeling of a Hot Gas Bypass Test Block for Centrifugal Compressors

The increasingly competitive building equipment and control industry pushes manufacturers to devote more resources each year to research and development, continually improving the performance and efficiency of their products to develop and maintain a competitive edge. Compressor development is an expensive endeavor because of prototyping and testing costs, but the cost and time required for testing can be minimized by developing a model of the compressor test block to predict its behavior with a given prototype compressor at specified operating conditions. This paper presents a thermodynamic model of a hot gas bypass test block used to evaluate centrifugal compressor performance at a compressor development facility. The test block uses cooling towers to reject the heat of compression to outdoor air, and experience has shown that the range of achievable compressor test conditions can be limited by outdoor air temperature and humidity, which control the heat rejection rate. Therefore, one goal of the model development was to provide a means for evaluating the feasibility of tests at given ambient conditions. By incorporating models of the cooling towers into the test block model, test operators now are able to predict the range of compressor suction and discharge conditions that can be tested under the current outdoor air conditions. A second goal of the model was to assist in selecting the orifice plate used in the orifice flow meter that measures mass flow through the compressor. Operators previously had to make an educated guess as to the best orifice plate size in advance of running the tests, but the model now identifies the orifice diameters that result in pressure drops within the desired range, minimizing the trial and error involved in testing. The model assumes that the system operates at steady-state conditions and uses a compressor map to model expected prototype compressor performance. Therefore, this paper focuses on the condenser and cooling tower models, which are the most important elements for predicting the impact of outdoor conditions on cycle performance. It is shown that the resulting model achieves reasonable agreement with experimental data and provides a useful orifice selection routine

Four-dimensional variational assimilation of ozone profiles from the Microwave Limb Sounder on the Aura satellite

Ozone profiles from the Microwave Limb Sounder (MLS) onboard the Aura satellite of the NASA's Earth Observing System (EOS) were experimentally added to the European Centre for Medium-range Weather Forecasts (ECMWF) four-dimensional variational (4D-var) data assimilation system of version CY30R1, in which total ozone columns from Scanning Imaging Absorption Spectrometer for Atmospheric CHartographY (SCIAMACHY) onboard the Envisat satellite and partial profiles from the Solar Backscatter Ultraviolet (SBUV/2) instrument onboard the NOAA-16 satellite have been operationally assimilated. As shown by results for the autumn of 2005, additional constraints from MLS data significantly improved the agreement of the analyzed ozone fields with independent observations throughout most of the stratosphere, owing to the daily near-global coverage and good vertical resolution of MLS observations. The largest impacts were seen in the middle and lower stratosphere, where model deficiencies could not be effectively corrected by the operational observations without the additional information on the ozone vertical distribution provided by MLS. Even in the upper stratosphere, where ozone concentrations are mainly determined by rapid chemical processes, dense and vertically resolved MLS data helped reduce the biases related to model deficiencies. These improvements resulted in a more realistic and consistent description of spatial and temporal variations in stratospheric ozone, as demonstrated by cases in the dynamically and chemically active regions. However, combined assimilation of the often discrepant ozone observations might lead to underestimation of tropospheric ozone. In addition, model deficiencies induced large biases in the upper stratosphere in the medium-range (5-day) ozone forecasts

Performance of an R-410A Room Air Conditioner Modified for Use with R-1234ze

This paper presents the results of a senior design project that challenged a team of undergraduate students to reduce the environmental impact of a room air conditioner (RAC) by reducing its energy consumption and/or use of high-GWP refrigerants. Over the course of an academic year, the team was able to investigate, design, model, evaluate, and build a prototype improved RAC. The team began by reviewing literature on approaches that have been proposed to meet or exceed existing energy efficiency and refrigerant selection regulations. Based on these findings and the specified needs of the project sponsor, the team evaluated the appropriateness of different concepts for improving the existing R-410A RAC design and decided to pursue modifications to adapt the unit for R-1234yf. The first step in the redesign process was to develop a thermodynamic model of the existing system. Because very little information was known about the performance of the individual components in the existing RAC, some rough performance estimates were obtained through measurements. The model of the existing system was then modified to provide the same cooling capacity as the original unit but using R-1234yf, and a replacement compressor was selected based on the model results. After the replacement compressor and resized capillary tubes were installed in the RAC, the team was asked to test the prototype unit using R-1234ze instead of R-1234yf. Therefore, the model was modified to predict the cooling capacity of the unit using R-1234ze as the working fluid. The unit was tested using an environmental chamber to simulate the outdoor air conditions and a large room as the indoor environment. Although this setup could not ensure steady-state operation, air temperature measurements indicated that the room temperature did not vary more than 1.5°F over 12 minutes of RAC operation. The cooling capacity calculated based on experimental measurements agreed within 3% of the model predictions. While the team was able to modify the RAC to operate with R-1234ze and was able to predict the unit’s performance with reasonable accuracy, the modifications required a significantly larger compressor and capillary tubes. Therefore, the project clearly illustrated that fitting within the space and weight constraints of window units presents a significant challenge to implementing R-1234ze in RACs

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually. The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp. and Trypanosoma brucei spp., respectively. These parasites have similar biology and genomic sequence, suggesting that all three diseases could be cured with drugs that modulate the activity of a conserved parasite target. However, no such molecular targets or broad spectrum drugs have been identified to date. Here we describe a selective inhibitor of the kinetoplastid proteasome (GNF6702) with unprecedented in vivo efficacy, which cleared parasites from mice in all three models of infection. GNF6702 inhibits the kinetoplastid proteasome through a non-competitive mechanism, does not inhibit the mammalian proteasome or growth of mammalian cells, and is well-tolerated in mice. Our data provide genetic and chemical validation of the parasite proteasome as a promising therapeutic target for treatment of kinetoplastid infections, and underscore the possibility of developing a single class of drugs for these neglected diseases

The effects of zeranol on the feedlot performance of beef bulls

Fifty-three cross-bred bulls, aged 5–7 mo, were divided at random into a nonimplanted control group of 26 bulls and a treatment group of 27 bulls, which were each implanted with 36 mg of zeranol on the 1st, 81st, and 155th day of the experiment. They were fed a high energy diet ad libitum for 168 days during which time liveweight and feed consumption were recorded at 2-wk intervals. Occasional measurements of scrotal circumference and serum T3 and T4 concentration were taken on 26 bulls (12 control, 14 implanted). At the end of 168 days the same 26 bulls were halter-broken in preparation for libido testing and semen evaluation. All bulls were slaughtered 236 days after the initial implanting, at which time a study was made of the behavior of 20 control and 20 treated bulls during the 6–7 h leading up to slaughter. There was a large (6.1%) but nonsignificant difference in rate of gain, with no difference in feed efficiency due to the implant. Zeranol was found to have no significant effect on sexual development, thyroid hormone concentration, behavior or carcass characteristics. There was, however, a four-times greater incidence (nonsignificant) of dark-cutting carcasses among the control bulls, than the treated bulls

Economic Stress of International Students: What Counselors Should Know

College students encounter high levels of stress due to intensive demands from developmental and academic tasks. In addition to the stress induced by developmental and academic tasks, economic stress adds substantial distress to college students. Economic contraction is known to bring up mental health concerns in society. Financial stress and diminished optimism are affected by distressful economic conditions. This study examined the different perceptions of economic stress between American students and international students of one English for Speakers of Other Language (ESOL) program. International students in this study sustained equally high economic stress but were more sensitive to the economic downturn. The results provide an opportunity to inform counselors how to better work with international students regarding their economic stress