Analysis of chlorpheniramine in human urine samples using dispersive liquid-liquid microextraction combined with high-performance liquid chromatography

A simple and environmentally friendly microextraction technique was used for determination of chlorpheniramine (CPM), an antihistamine drug, in human urine samples using dispersive liquid-liquid microextraction (DLLME) followed by high performance liquid chromatography with diode array detection (HPLC-DAD). In this extraction technique, an appropriate mixture of acetonitrile (disperser solvent) and carbon tetrachloride (extraction solvent) was rapidly injected into the urine sample containing the target analyte. Tiny droplets of extractant were formed and dispersed into the sample solution and then sedimented at the bottom of the conical test tube by centrifugation. Under optimal conditions, the calibration curve was linear in the range of 0.055-5.5 µg mL-1, with a detection limit of 16.5 ng mL-1. This proposed method was successfully applied to the analysis of real urine samples. Low consumption of toxic organic solvents, simplicity of operation, low cost and acceptable figures of merit are the main advantages of the proposed technique

Ultrasound propagation through Kelvin-Helmholtz and Von Karman instabilities

International audienceno abstrac

Validation of predicted path of thermally deflected ultrasonic waves

International audienceno abstrac

Study of ultrasonic propagation through Kelvin-Helmoltz instabilities for monitoring high-temperature fluid

International audienceno abstrac

Simplified modelling of liquid sodium medium with temperature gradient from thermohydraulic measurements to simulate wave propagation in liquid sodium. Application to ultrasonic thermometry in Sodium Fast Reactor

International audienceno abstrac

Etude d’une méthode ultrasonore d’estimation des températures du sodium liquide en sortie de cœur de SFR

National audienceno abstrac

Avancées pour l’inspection non destructive par des méthodes ultrasonores des réacteurs refroidis au sodium liquide

National audienceno abstrac