The isodiametric problem with lattice-point constraints

In this paper, the isodiametric problem for centrally symmetric convex bodies in the Euclidean d-space R^d containing no interior non-zero point of a lattice L is studied. It is shown that the intersection of a suitable ball with the Dirichlet-Voronoi cell of 2L is extremal, i.e., it has minimum diameter among all bodies with the same volume. It is conjectured that these sets are the only extremal bodies, which is proved for all three dimensional and several prominent lattices.Comment: 12 pages, 4 figures, (v2) referee comments and suggestions incorporated, accepted in Monatshefte fuer Mathemati

Intentionally fabricated autobiographical memories

Participants generated both autobiographical memories (AMs) that they believed to be true and intentionally fabricated autobiographical memories (IFAMs). Memories were constructed while a concurrent memory load (random 8-digit sequence) was held in mind or while there was no concurrent load. Amount and accuracy of recall of the concurrent memory load was reliably poorer following generation of IFAMs relative to AMs. There was, however, no reliable effect of load on memory generation times however IFAMs always took longer to construct than AMs. Finally, replicating previous findings, fewer IFAMs had a field perspective than AMs, IFAMs were less vivid than AMs, and IFAMs contained more motion words (indicative of increased cognitive load). Taken together these findings show a pattern of systematic differences that mark out IFAMs and they also show that IFAMs can be identified indirectly by lowered performance on concurrent tasks that increase cognitive load

Radio astrometry with chromatic AGN core positions

Aims: The effect of frequency-dependent AGN core positions (``core-shifts'') on radio Very Long Baseline Interferometry (VLBI) global astrometry measurements is investigated. Methods: The basic equations relating to VLBI astrometry are reviewed, including the effects of source structure. A power-law representation of core-shifts, based on both observations and theoretical considerations of jet conditions, is incorporated. Results: It is shown that, in the presence of core-shifts, phase and group-delay astrometry measurements yield different positions. For a core displacement from the jet base parametrized by Delta x (lambda) = k lambda^beta group delays measure a ``reduced'' core-shift of (1-beta) Delta x (lambda). For the astrophysically-significant case of beta = 1, group delays measure no shift at all, giving the position of the jet base. At 8.4 GHz an estimated typical offset between phase and group-delay positions of ~170 uas is smaller than the current ~250 uas precision of group-delay positions of the sources used to define the ICRF; however, this effect must be taken into account for future measurements planned with improved accuracy when comparing with optical positions of AGN to be obtained with the GAIA mission.Comment: Accepted for publication in Astronomy & Astrophysics, 4 page

The ‘common sense’ memory belief system and its implications

Memory experts, the police, and the public, completed a memory questionnaire containing a series of statements about autobiographical memory. The statements covered issues such as the nature of memory, determinants of accuracy, the relation of emotion and trauma to memory, and respondents indicated their agreement/disagreement with each of the statements. The police and public were found to share a ‘common sense’ memory belief system (CSMBS) in which memories were like videos/photographs, and accuracy was determined by the number of details recalled and also by their vividness. In direct contrast the scientific memory belief system, held by memory researchers, largely based on scientific evidence, was the opposite of the CSMBS and memories were judged to be fragmentary, number of details and their nature did not predict accuracy, and memories and their details could be in error and even false. The problematic nature of the CSBMS, which is pervasive in society, in raising the probability of flawed judgments of memory evidence is considered and, by way of illustration, applied to the (very high) attrition rate in complaints of rape

Amnesia and future thinking: Exploring the role of memory in the quantity and quality of episodic future thoughts.

OBJECTIVES: To examine the impact of memory accessibility on episodic future thinking. DESIGN: Single-case study of neurological patient HCM and an age-matched comparison group of neurologically Healthy Controls. METHODS: We administered a full battery of tests assessing general intelligence, memory, and executive functioning. To assess autobiographical memory, the Autobiographical Memory Interview (Kopelman, Wilson, & Baddeley, 1990. The Autobiographical Memory Interview. Bury St. Edmunds, UK: Thames Valley Test Company) was administered. The Past Episodic and Future Episodic sections of Dalla Barba's Confabulation Battery (Dalla Barba, 1993, Cogn. Neuropsychol., 1, 1) and a specifically tailored Mental Time Travel Questionnaire were administered to assess future thinking in HCM and age-matched controls. RESULTS: HCM presented with a deficit in forming new memories (anterograde amnesia) and recalling events from before the onset of neurological impairment (retrograde amnesia). HCM's autobiographical memory impairments are characterized by a paucity of memories from Recent Life. In comparison with controls, two features of his future thoughts are apparent: Reduced episodic future thinking and outdated content of his episodic future thoughts. CONCLUSIONS: This article suggests neuropsychologists should look beyond popular conceptualizations of the past-future relation in amnesia via focussing on reduced future thinking. Investigating both the quantity and quality of future thoughts produced by amnesic patients may lead to developments in understanding the complex nature of future thinking disorders resulting from memory impairments. PRACTITIONER POINTS: We highlight the clinical importance of examining the content of future thoughts in amnesic patients, rather than only its quantitative reduction. We propose an explanation of how quantitative and qualitative aspects of future thinking could be affected by amnesia. This could provide a useful approach to understand clinical cases of impaired prospection. LIMITATIONS: Systematic group investigations are required to fully examine our hypothesis. Although the current study utilized typical future thinking measures, these may be limited and we highlight the need to develop clinically relevant measures of prospection

Why are we not flooded by involuntary thoughts about the past and future? Testing the cognitive inhibition dependency hypothesis

© The Author(s) 2018In everyday life, involuntary thoughts about future plans and events occur as often as involuntary thoughts about the past. However, compared to involuntary autobiographical memories (IAMs), such episodic involuntary future thoughts (IFTs) have become a focus of study only recently. The aim of the present investigation was to examine why we are not constantly flooded by IFTs and IAMs given that they are often triggered by incidental cues while performing undemanding activities. One possibility is that activated thoughts are suppressed by the inhibitory control mechanism, and therefore depleting inhibitory control should enhance the frequency of both IFTs and IAMs. We report an experiment with a between-subjects design, in which participants in the depleted inhibition condition performed a 60-min high-conflict Stroop task before completing a laboratory vigilance task measuring the frequency of IFTs and IAMs. Participants in the intact inhibition condition performed a version of the Stroop task that did not deplete inhibitory control. To control for physical and mental fatigue resulting from performing the 60-min Stroop tasks in experimental conditions, participants in the control condition completed only the vigilance task. Contrary to predictions, the number of IFTs and IAMs reported during the vigilance task, using the probe-caught method, did not differ across conditions. However, manipulation checks showed that participants’ inhibitory resources were reduced in the depleted inhibition condition, and participants were more tired in the experimental than in the control conditions. These initial findings suggest that neither inhibitory control nor physical and mental fatigue affect the frequency of IFTs and IAMs.Peer reviewedFinal Published versio

Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis

Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to mesenchymal transition. We therefore assessed the therapeutic impact of ERK1/2 inhibition using a MEK inhibitor in the rat 5/6 subtotal nephrectomy (SNx) model of kidney fibrosis. There was a twentyfold upregulation in phospho-ERK1/2 expression in the kidney after SNx in Male Wistar rats. Rats undergoing SNx became hypertensive, proteinuric and developed progressive kidney failure with reduced creatinine clearance. Treatment with the MEK inhibitor, CI-1040 abolished phospho- ERK1/2 expression in kidney tissue and prevented phospho-ERK1/2 expression in peripheral lymphocytes during the entire course of therapy. CI-1040 had no impact on creatinine clearance, proteinuria, glomerular and tubular fibrosis, and α-smooth muscle actin expression. However, inhibition of ERK1/2 activation led to significant compensatory upregulation of the MAP kinases, p38 and JNK in kidney tissue. CI-1040 also increased the expression of plasminogen activator inhibitor-1 (PAI-1), a key inhibitor of plasmin-dependent matrix metalloproteinases. Thus inhibition of ERK1/2 activation has no therapeutic effect on kidney fibrosis in SNx possibly due to increased compensatory activation of the p38 and JNK signalling pathways with subsequent upregulation of PAI-1

Spontaneous and deliberate future thinking: A dual process account

© 2019 Springer Nature.This is the final published version of an article published in Psychological Research, licensed under a Creative Commons Attri-bution 4.0 International License. Available online at: https://doi.org/10.1007/s00426-019-01262-7.In this article, we address an apparent paradox in the literature on mental time travel and mind-wandering: How is it possible that future thinking is both constructive, yet often experienced as occurring spontaneously? We identify and describe two ‘routes’ whereby episodic future thoughts are brought to consciousness, with each of the ‘routes’ being associated with separable cognitive processes and functions. Voluntary future thinking relies on controlled, deliberate and slow cognitive processing. The other, termed involuntary or spontaneous future thinking, relies on automatic processes that allows ‘fully-fledged’ episodic future thoughts to freely come to mind, often triggered by internal or external cues. To unravel the paradox, we propose that the majority of spontaneous future thoughts are ‘pre-made’ (i.e., each spontaneous future thought is a re-iteration of a previously constructed future event), and therefore based on simple, well-understood, memory processes. We also propose that the pre-made hypothesis explains why spontaneous future thoughts occur rapidly, are similar to involuntary memories, and predominantly about upcoming tasks and goals. We also raise the possibility that spontaneous future thinking is the default mode of imagining the future. This dual process approach complements and extends standard theoretical approaches that emphasise constructive simulation, and outlines novel opportunities for researchers examining voluntary and spontaneous forms of future thinking.Peer reviewe

Optical Monitoring of PKS 1510-089: A Binary Black Hole System?

Three deep flux minima were observed with nearly the same time-scales and intervals for the blazar PKS 1510-089 in the past few years. A binary black hole system was proposed to be at the nucleus of this object, and a new minimum was predicted to occur in 2002 March. We monitored this source with a 60/90 cm Schmidt telescope from 2002 February to April. In combination with the data obtained by Xie et al. (2004) in the same period, we presented for the 2002 minimum a nearly symmetric light curve, which would be required by an eclipsing model of a binary black hole system. We also constrained the time-scale of the minimum to be 35 min, which is more consistent with the time-scales ~42 min of the three previous minima than the 89 min time-scale given by the same authors. The wiggling miniarcsecond radio jet observed in this object is taken as a further evidence for the binary black hole system. The `coupling' of the periodicity in light curve and the helicity in radio jet is discussed in the framework of a binary black hole system.Comment: 5 pages, 4 figures, accepted by MNRA

Protecting eyewitness evidence: Examining the efficacy of a self-administered interview tool

Given the crucial role of eyewitness evidence, statements should be obtained as soon as possible after an incident. This is not always achieved due to demands on police resources. Two studies trace the development of a new tool, the Self-Administered Interview (SAI), designed to elicit a comprehensive initial statement. In Study 1, SAI participants reported more correct details than participants who provided a free recall account, and performed at the same level as participants given a Cognitive Interview. In Study 2, participants viewed a simulated crime and half recorded their statement using the SAI. After a delay of 1 week, all participants completed a free recall test. SAI participants recalled more correct details in the delayed recall task than control participants