Impact of a nationwide public campaign on delays and outcome in Swiss patients with acute coronary syndrome

Background: To improve the outcome in patients with acute coronary syndrome (ACS), public campaigns have been launched aimed at shortening presentation delays and allowing more efficient treatment. Their impact is uncertain. Methods: Pre-hospital delays and outcome in patients with ACS included in the Swiss National AMIS Plus registry were assessed prospectively before and after a nationwide multimedia campaign ('HELP') by the Swiss Heart Foundation in 2007. The campaign aimed at better awareness of symptoms, increasing knowledge in laymen of resuscitation and more rapid access to medical services. The primary study endpoint was the time between onset of symptoms and hospital admission. Secondary endpoints were successful out-of-hospital resuscitation, symptoms upon admission, and outcome. Results: Between January 2005 and December 2008, 8906 ACS patients (61% ST-segment elevation myocardial infarction (STEMI), 39% non-ST-segment elevation myocardial infarction/unstable angina pectoris (NSTEMI/UAP), mean age 65 ± 13 years, 75% males) admitted within 24 hours after onset of symptoms were enrolled. The median pre-hospital delay was reduced from 197 minutes during the pre-intervention period to 180 minutes during the post-intervention period (reduction 10% (95% confidence interval (CI) 6-14%); P < 0.001), in STEMI (reduction 10% (95% CI 5-14%); P < 0.001) and NSTEMI patients (reduction 11% (95% CI 4-17%); P = 0.001), due to pronounced effects in males (reduction 12% (95% CI 7-16%); P < 0.001) and in patients ≤75 years (reduction 12% (95% CI 8-16%); P < 0.001). Out-of-hospital resuscitation increased (odds ratio (OR) 1.26 (95% CI 1.06-1.54); P = 0.02). Overall outcome remained unchanged, however, the rate of re-infarction showed a decrease (OR 0.58 (95% CI 0.36-0.91); P = 0.021). Conclusions: After a nationwide educational campaign, shorter pre-hospital delays were observed, and more patients were able to be treated promptly. These results may be useful in planning future health strategies to improve management and outcome of patients with ACS, especially in female and elderly patients

Trabalho da enfermagem e distúrbio musculoesquelético: revisão das pesquisas sobre o tema Trabajo de la enfermería y disturbio musculoesquelético: revisión de las investigaciones acerca del tema. The nursing work and musculoskeletal disorders: a review of the researches about the theme

Este estudo teve por objetivo identificar a produção brasileira de teses e dissertações sobre os distúrbios musculoesqueléticos em trabalhadores de enfermagem. As publicações foram pesquisadas no banco de teses e dissertações do Portal CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) e nos catálogos da ABEn (Associação Brasileira de Enfermagem), no período de 1978 a 2004. Foram selecionados os resumos de teses e dissertações de acordo com os seguintes critérios: desfecho "musculoesquelético" em população de trabalhadores de enfermagem. Dezoito estudos preencheram os critérios de inclusão. Destes, dois tiveram abordagem qualitativa; um, abordagem qualiquantitativa; e quinze, abordagem quantitativa. Os Cursos de Pós-graduação da Universidade de São Paulo e da Universidade Federal do Rio de Janeiro foram os que se destacaram em produções na temática em tela. Os trabalhos apontam tanto para o crescente adoecimento musculoesquelético dos trabalhadores de enfermagem quanto para as inadequadas condições de trabalho como fator de risco para esse adoecimento.<br>Este estudio tuvo por objetivo identificar la producción brasileña de tesis y disertaciones acerca los disturbios musculoesqueléticos en trabajadores de enfermería. Las publicaciones han sido investigadas en el Banco de Tesis y Disertaciones del Portal CAPES "Coordenação de Aperfeiçoamento de Pessoal de Nível Superior" y en los catálogos de la ABEn - "Associação Brasileira de Enfermagem", en el período de 1978 a 2004. Fueron seleccionados los resúmenes de tesis y disertaciones de acuerdo con los siguientes criterios: el cierre "musculoesquelético" en población de trabajadores de enfermería. Dieciocho estudios cumplían los criterios de inclusión. De estos, dos tuvieron abordaje cualitativo, un cuali-cuantitativo y quince abordaje cuantitativo. Los cursos de Postgrado de la Universidad de São Paulo y de la Universidad Federal del Rio de Janeiro fueron los que se destacaron en producciones en la temática en discusión. Los trabajos señalan tanto para el hecho de adolecer musculoesquelético creciente de los trabajadores de enfermería cuanto para las inadecuadas condiciones de trabajo como factor de riesgo para ese adolecer.<br>This study aimed to identify the Brazilian scientific production (thesis and dissertations) about musculoskeletal disorders in nursing workers. The publications were searched in the Banco de Teses e Dissertações (thesis and dissertations collection) of the Portal CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - (Brazilian Government Agency) and the catalogues of the Associação Brasileira de Enfermagem ABEN (Brazilian Nursing Association). The period researched was 1978-2004. The criterion used to select the thesis and dissertations' abstract was the outcome "musculoskeletal" in nursing population. Eighteen studies matched the criterion. Regarding to the research approach, 2 of them presented a qualitative one, 1 quantitative qualitative one; and 15 quantitative one. The majority of them were from pos-graduated courses of Universidade de São Paulo and Universidade Federal do Rio de Janeiro. The studies pointed out to the growing number of nursing workers who have became sick due to musculoskeletal disorders; as well as to the poor conditions of work as a risk factor for this

The promoter signatures in rice LEA genes can be used to build a co-expressing LEA gene network

10.1007/s12284-008-9017-4Rice12177-18

Effect of polyphenols dietary grape by-products on chicken patties

An experiment was conducted to study the dietary effect that the inclusion (40 g kg) of grape seed (GS), grape skin (SS), grape pomace (GP), and (0.2 g kg) of vitamin E (E) had on the composition and microbiological quality of chicken breast meat and on the physico-chemical parameters (TBARS, pH, color, Kramer shear force), sensorial characteristics, and microbiological quality of chicken breast meat patties during chilled storage (0, 3, 6, and 9 days) at 2 °C. In general, proximate composition and microbial counts of the raw chicken breast meat and the patties were not affected. Lower TBARS values were detected in patties formulated with breast meat obtained from birds fed E, SS, and GP diets. No clear effect was observed on the color or textural characteristics of the different patties. The addition of SS and GP in chicken diets reduced TBARS values showing some improvement in the oxidative stability of breast patties without affecting its technological properties, sensorial attributes, or microbial quality.The authors thank the MINECO and CSIC for financial support of Projects AGL2012-31355/GAN, AGL2014-53207-C2-1-R, and the Intramural 2014470E073. In addition, we are grateful to CAM and ESI Funds for financially supporting project MEDGAN-CM S2013/ABI2913). We would also like to thank MIUR and UNIMOL for the Ph.D. fellowship of Maria Nardoia.Peer Reviewe