8,536 research outputs found
Pinning it down: An evaluation of Pinterest’s function in the British academic library
University libraries have found a useful resource for themselves in many social media platforms. At Leeds Beckett University Library (formerly Leeds Metropolitan University), Twitter has proved a popular way to connect with students, other libraries and universities. Our Twitter following has exceeded 3,800, and our library Facebook had over 1,100 followers by May 2014. While we continue to develop these two sites, however, we acknowledge that we are not part of a stable environment. Social media is faddish; the favoured platforms change frequently. Facebook has largely taken custom away from Myspace, while Myspace used to tussle for users with Bebo, and Google Plus has taken their share of professional networks away from other platforms. With this in mind, any organisation using social media has to think about whether they should use – and if so, how to use – emerging virtual social networks
Holographic photography of high velocity particles
Fourier transform hologram camera increases the velocity range for holography by a factor of 10 to 1000. Two different optical systems, using a triangular arrangement of beam splitters and a mirror to illuminate the object from two directions, are investigated
Feasibility Study of Velocity Synchronized Fourier Transform Hologram Camera System
Velocity synchronized Fourier transform hologram camera syste
One-Pot Phosphate-Mediated Synthesis of Novel 1,3,5-Trisubstituted Pyridinium Salts: A New Family of S. aureus Inhibitors
Polysubstituted pyridinium salts are valuable pharmacophores found in many biologically active molecules. Their synthesis typically involves the use of multistep procedures or harsh reaction conditions. Here, we report water-based phosphate mediated reaction conditions that promote the condensation of arylacetaldehydes with amines to give 1,3,5-pyridinium salts. The reaction, carried out at pH 6, provides conditions suitable for the use of less stable aldehydes and amines in this Chichibabin pyridine condensation. The evaluation of selected 1,3,5-trisubstituted pyridinium salts highlighted that they can inhibit the growth of S. aureus in the low μg/mL range. The synthetic accessibility of these compounds and preliminary growth inhibition data may pave the way towards the discovery of new anti-bacterials based on the 1,3,5-trisubstituted pyridinium scaffold
An investigation of cortical neuroplasticity following stroke in adults: is there evidence for a critical window for rehabilitation?
Evidence in animal stroke models suggests that neuroplasticity takes place maximally in a specific time window after an ischaemic lesion, which may coincide with the optimal time to intervene with rehabilitation. The aim of this study is to investigate neurophysiological evidence for a "critical window" of enhanced neuroplasticity in patients following ischaemic stroke, and establish its duration. We will also investigate changes in cortical inhibition following stroke, and the influence this has on functional recovery
Recommended from our members
Trust-level risk identification guidance in the NHS East of England.
BACKGROUND: In healthcare, a range of methods are used to improve patient safety through risk identification within the scope of risk management. However, there is no evidence determining what trust-level guidance exists to support risk identification in healthcare organisations. This study therefore aimed to determine such methods through the content analysis of trust-level risk management documents. METHOD: Through Freedom of Information Act, risk management documents were requested from each acute, mental health and ambulance trust in the East of England region of NHS for content analysis. Received documents were also compared with guidance from other safety-critical industries to capture differences between the documents from those industries, and learning points to the healthcare field. RESULTS: A total of forty-eight documents were received from twenty-one trusts. Incident reporting was found as the main method for risk identification. The documents provided insufficient support for the use of prospective risk identification methods, such as Prospective Hazard Analysis (PHA) methods, while the guidance from other industries extensively promoted such methods. CONCLUSION: The documents provided significant insight into prescribed risk identification practice in the chosen region. Based on the content analysis and guidance from other safety-critical industries, a number of recommendations were made; such as introducing the use of PHA methods in the creation and revision of risk management documents, and providing individual guidance on risk identification to promote patient safety further.This is the author accepted manuscript. The final version is available from IOS Press via http://dx.doi.org/10.3233/JRS-15065
Older adults experiences of rehabilitation in acute health care
Rehabilitation is a key component of nursing and allied healthcare professionals’ roles in most health and social care settings. This paper reports on stage 2 of an action research project to ascertain older adult's experience of rehabilitation. Twenty postdischarge interviews were conducted and the interview transcripts were analysed using thematic content analysis. All older adults discharged from an acute older acute rehabilitation ward to their own homes in the community were eligible to participate. The only exclusion criterion was older adults who were thought to be unable to give consent to participate by the nurse in charge and the researcher. Whilst 92 older adults were eligible to participate in this research study, only 20 were interviewed. The findings from this study suggest that older adults valued communication with health professionals but were aware of their time constraints that hindered communication. This study suggests that both nurses and allied health professionals are not actively providing rehabilitative services to promote health and well-being, which contradicts the focus of active ageing. Furthermore, there was evidence of unmet needs on discharge, and older adults unable to recall the professions that were involved in their interventions and the rationale for therapy input. It is suggested that further research is needed to explore the effectiveness of allied health rehabilitation in the acute setting. This study highlights the need for further research into older adults’ perceptions of the rehabilitation process in the acute setting
Exploring the equity of GP practice prescribing rates for selected coronary heart disease drugs: a multiple regression analysis with proxies of healthcare need
Background
There is a small, but growing body of literature highlighting inequities in GP practice prescribing rates for many drug therapies. The aim of this paper is to further explore the equity of prescribing for five major CHD drug groups and to explain the amount of variation in GP practice prescribing rates that can be explained by a range of healthcare needs indicators (HCNIs).
Methods
The study involved a cross-sectional secondary analysis in four primary care trusts (PCTs 1–4) in the North West of England, including 132 GP practices. Prescribing rates (average daily quantities per registered patient aged over 35 years) and HCNIs were developed for all GP practices. Analysis was undertaken using multiple linear regression.
Results
Between 22–25% of the variation in prescribing rates for statins, beta-blockers and bendrofluazide was explained in the multiple regression models. Slightly more variation was explained for ACE inhibitors (31.6%) and considerably more for aspirin (51.2%). Prescribing rates were positively associated with CHD hospital diagnoses and procedures for all drug groups other than ACE inhibitors. The proportion of patients aged 55–74 years was positively related to all prescribing rates other than aspirin, where they were positively related to the proportion of patients aged >75 years. However, prescribing rates for statins and ACE inhibitors were negatively associated with the proportion of patients aged >75 years in addition to the proportion of patients from minority ethnic groups. Prescribing rates for aspirin, bendrofluazide and all CHD drugs combined were negatively associated with deprivation.
Conclusion
Although around 25–50% of the variation in prescribing rates was explained by HCNIs, this varied markedly between PCTs and drug groups. Prescribing rates were generally characterised by both positive and negative associations with HCNIs, suggesting possible inequities in prescribing rates on the basis of ethnicity, deprivation and the proportion of patients aged over 75 years (for statins and ACE inhibitors, but not for aspirin)
Prioritization of fish communities with a view to conservation and restoration on a large scale European basin, the Loire (France)
The hierarchical organization of important sites for the conservation or the
restoration of fish communities is a great challenge for managers, especially because of
financial or time constraints. In this perspective, we developed a methodology, which is
easy to implement in different locations. Based on the fish assemblage characteristics of
the Loire basin (France), we created a synthetic conservation value index including the
rarity, the conservation status and the species origin. The relationship between this new
synthetic index and the Fish-Based Index allowed us to establish a classification protocol
of the sites along the Loire including fish assemblages to be restored or conserved. Sites
presenting disturbed fish assemblages, a low rarity index, few threatened species, and a
high proportion of non-native species were considered as important for the restoration of
fish biodiversity. These sites were found mainly in areas where the assemblages are
typical of the bream zone, e.g. with a higher number of eurytopic and limnophilic
species. On the contrary, important sites for conservation were defined as having an
important conservation potential (high RI, a lot of threatened species, and few nonnatives
fish species) and an undisturbed fish assemblage similar to the expected community
if habitats are undisturbed. Important sites for conservation were found in the
Loire basin’s medium reaches which host assemblages typical for the grayling and the
barbell zones, e.g. with a higher number of rheophilic species. The synthetic conservation value index could be adapted and completed with other criteria according to
management priorities and capacities
- …
