Modeling the Effect of Bandwidth Allocation on Network Performance

In this paper, a new channel capacity model for interferencelimited systems was obtained by transforming the Shannon-Hartley theorem for channel capacity. To emulate an operational system, a dashboard Motorola monitoring device was used to collect data from a group of Base Stations (BSs) serving (a section of) the Nigerian air space and belonging to one of the existing network carriers. Our findings revealed that the uplink and downlink throughputs of the existing system were not impressive even when there was uniform sharing of bottlenecks across the BSs. Using MATLAB, simulations were then performed by extending these data, subject to ideal environmental constraints. Results obtained revealed the following: (i) The Shannon-Hartley model performed as expected for no-interference systems (TDMA and FDMA), but as the bandwidth improved, only limited number of users could access the network in the presence of increased SNR; (ii) The proposed model showed improved performance for CDMA networks, but further increase in the bandwidth did not benefit the network; (iii) A reliability measure such as the spectral efficiency is therefore useful to redeem the limitation in (ii).Keywords: Coverage Capacity, CDMA, Mobile Network, Network Throughpu

Towards Securing the Home Computer: a modification of the USB Port

Hundreds of millions of people use the home computer everyday for different purposes. These systems use the universal serial bus (USB) disk for day to day transfer of data, communication and other applications. The USB as a flexible tool for data transfer raises security concerns relatively to a potential loss of assets. This paper therefore demonstrates how a modification of the USB port can improve the security of the home computer.Keywords: home computer, operating system, threats, Universal Serial Bus (USB)

Towards Securing the Home Computer: a modification of the USB Port

Hundreds of millions of people use the home computer everyday for different purposes. These systems use the universal serial bus (USB) disk for day to day transfer of data, communication and other applications. The USB as a flexible tool for data transfer raises security concerns relatively to a potential loss of assets. This paper therefore demonstrates how a modification of the USB port can improve the security of the home computer.Keywords: home computer, operating system, threats, Universal Serial Bus (USB)Journal of the Nigerian Association of Mathematical Physics, Volume 20 (March, 2012), pp 461 – 46

Changing the opinions, beliefs and attitudes of the Efiks, Quas and Efuts of Calabar Municipality towards the practice of female circumcision

Objective: To determine the opinion of the Efiks, Quas and Efuts of old Calabar district towards the practice of female circumcision. To examine the beliefs of the Efiks, Quas and Efuts of Calabar towards the practice of female circumcision. To determine the attitude of the Efiks, Quas and Efuts of Calabar towards the practice of female circumcision.Methods: In order to successfully carry out the study, three research questions and hypothesis were formulated. Literatures were reviewed based on the research variables. The research instrument used for data collection was questionnaire which was administered on three hundred and six (306) respondents who served as the sample for the study. Their responses were analyzed using frequencies, and percentages. Results showed that more than 50% are not in support of the practice and in fact more than 64% will not want their daughters circumcised.Results: It is observed that majority of educated, well informed and enlightened individuals who are aware of the harmful effects of the female circumcision abhors it. To this extent, proper education, and enlightenment, should be encouraged. Religions and cosmopolitan nature of the city are key to influencing the opinions, beliefs and attitude of the people living there. And finally, majority of the people think that the practice of female circumcision is decreasing in the city. Based on these findings information should continue to be disseminated using mass media and local languages for complete eradication and permanent attitudinal change.Conclusions: This work highlight the influence of public education and increase awareness from both the rural and urban communities so rooted to their cultures of female circumcision in old Calabar district as bad practice and unacceptable tradition in the 21st century world of today.</jats:p

Detecting and targeting senescent cells using molecularly imprinted nanoparticles

The progressive accumulation of senescent cells in tissues in response to damage importantly contributes to pathophysiological conditions such as fibrosis, diabetes, cancer, Alzheimer's and ageing. Consistent with this, eliminating senescent cells prolongs the lifespan and healthspan in animals and ameliorates certain diseases. Detecting and clearing senescent cells from human tissues could therefore have a significant diagnostic and prognostic impact. However, identifying senescent cells in vivo has proven to be complex. To address this, we characterized and validated a panel of novel membrane markers of senescence. Here, we show the application of molecularly imprinted nanoparticles (nanoMIPs) against an extracellular epitope of one of these markers, B2M, to detect senescent cells in vitro and in vivo. We show that nanoMIPs do not elicit toxic responses in the cells or in mice and successfully recognize old animals, which have a higher proportion of senescent cells in their organs. Importantly, nanoMIPs loaded with drugs can specifically kill senescent cells. Our results provide a proof-of-principle assessment of specific and safe nanotechnology-based approaches for senescent cell detection and clearance with potential clinical relevance

Detecting and targeting senescent cells using molecularly imprinted nanoparticles

The progressive accumulation of senescent cells in tissues in response to damage importantly contributes to pathophysiological conditions such as fibrosis, diabetes, cancer, Alzheimer's and ageing. Consistent with this, eliminating senescent cells prolongs the lifespan and healthspan in animals and ameliorates certain diseases. Detecting and clearing senescent cells from human tissues could therefore have a significant diagnostic and prognostic impact. However, identifying senescent cells in vivo has proven to be complex. To address this, we characterized and validated a panel of novel membrane markers of senescence. Here, we show the application of molecularly imprinted nanoparticles (nanoMIPs) against an extracellular epitope of one of these markers, B2M, to detect senescent cells in vitro and in vivo. We show that nanoMIPs do not elicit toxic responses in the cells or in mice and successfully recognize old animals, which have a higher proportion of senescent cells in their organs. Importantly, nanoMIPs loaded with drugs can specifically kill senescent cells. Our results provide a proof-of-principle assessment of specific and safe nanotechnology-based approaches for senescent cell detection and clearance with potential clinical relevance

A comparison of methods to assess cell mechanical properties

International audienc