535 research outputs found

    Optimal phasor data concentrator installation for traffic reduction in smart grid wide-area monitoring systems

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    Conference Theme: the Power of Global CommunicationsSymposium on Selected Areas in CommunicationsAs one of the core components in wide-area monitoring systems (WAMS), phasor measurement units (PMUs) acquire highly accurate and time-synchronized phasor data at high frequency for smart grid monitoring, protection, and control. Despite the advantages of PMUs, they do generate much data and create a heavy burden on the communication network. One way of alleviating such burden is to install phasor data concentrators (PDC) across the power system to concentrate data generated by the PMUs. Although PDCs are expensive as well, this may still be a much cheaper and more practical option than building a high bandwidth network for WAMS. Therefore, it is very important to solve the optimal PDC installation problem so as to achieve a desired level of traffic reduction. This paper is the first to address this problem and we give solutions for the IEEE 14-bus, 30-bus, and 57-bus systems.published_or_final_versio

    Communication-oriented smart grid framework

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    Upgrading the existing electricity grids into smart grids relies heavily on the development of information and communication technology which supports a highly reliable real-time monitoring and control system as well as coordination of various electricity utilities and market participants. In this upgrading process, smart grid communication is the key to success, and a simple but complete, innovative but compatible high-level communication-oriented smart grid framework is needed. This paper proposes a simple and flexible three-entity framework, so that devices employing the existing technologies are supported and can interoperate with those employing new technologies. © 2011 IEEE.published_or_final_versionThe 2nd IEEE International Conference on Smart Grid Communications (SmartGridComm 2011), Brussels, Belgium, 17-20 October 2011. In Proceedings of 2nd SmartGridComm, 2011, p. 61-6

    Transitions of care from child and adolescent mental health services to adult mental health services (TRACK Study) : a study of protocols in Greater London

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    Background: Although young people's transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) in England is a significant health issue for service users, commissioners and providers, there is little evidence available to guide service development. The TRACK study aims to identify factors which facilitate or impede effective transition from CAHMS to AMHS. This paper presents findings from a survey of transition protocols in Greater London. Methods: A questionnaire survey (Jan-April 2005) of Greater London CAMHS to identify transition protocols and collect data on team size, structure, transition protocols, population served and referral rates to AMHS. Identified transition protocols were subjected to content analysis. Results: Forty two of the 65 teams contacted (65%) responded to the survey. Teams varied in type (generic/targeted/in-patient), catchment area (locality-based, wider or national) and transition boundaries with AMHS. Estimated annual average number of cases considered suitable for transfer to AMHS, per CAMHS team (mean 12.3, range 0–70, SD 14.5, n = 37) was greater than the annual average number of cases actually accepted by AMHS (mean 8.3, range 0–50, SD 9.5, n = 33). In April 2005, there were 13 active and 2 draft protocols in Greater London. Protocols were largely similar in stated aims and policies, but differed in key procedural details, such as joint working between CAHMS and AMHS and whether protocols were shared at Trust or locality level. While the centrality of service users' involvement in the transition process was identified, no protocol specified how users should be prepared for transition. A major omission from protocols was procedures to ensure continuity of care for patients not accepted by AMHS. Conclusion: At least 13 transition protocols were in operation in Greater London in April 2005. Not all protocols meet all requirements set by government policy. Variation in protocol-sharing organisational units and transition process suggest that practice may vary. There is discontinuity of care provision for some patients who 'graduate' from CAMHS services but are not accepted by adult services

    IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-kB activation

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    Hepatocellular carcinoma (HCC) is one of the major malignancies worldwide and is associated with poor prognosis due to the high incidences of metastasis and tumor recurrence. Our previous study showed that overexpression of p21-activated protein kinase 1 (PAK1) is frequently observed in HCC and is associated with a more aggressive tumor behavior, suggesting that PAK1 is a potential therapeutic target in HCC. In the current study, an allosteric small molecule PAK1 inhibitor, IPA-3, was evaluated for the potential in suppressing hepatocarcinogenesis. Consistent with other reports, inhibition of PAK1 activity was observed in several human HCC cell lines treated with various dosages of IPA-3. Using cell proliferation, colony formation and BrdU incorporation assays, we demonstrated that IPA-3 treatment significantly inhibited the growth of HCC cells. The mechanisms through which IPA-3 treatment suppresses HCC cell growth are enhancement of apoptosis and blockage of activation of NF-κB. Furthermore, our data suggested that IPA-3 not only inhibits the HCC cell growth, but also suppresses the metastatic potential of HCC cells. Nude mouse xenograft assay demonstrated that IPA-3 treatment significantly reduced the tumor growth rate and decreased tumor volume, indicating that IPA-3 can suppress the in vivo tumor growth of HCC cells. Taken together, our demonstration of the potential preclinical efficacy of IPA-3 in HCC provides the rationale for cancer therapy.published_or_final_versio

    The impact of peer mentoring on students’ physical activity and mental health

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    Purpose – A peer-mentoring scheme was implemented in a secondary school using a physical activity (PA) intervention to improve mental health outcomes of students who were at risk of developing mental ill health. These students are referred to as mentees. The evaluation was a qualitative design using focus groups and semi-structured interviews. The participants reported an increase in PA in both peer mentors and mentees. By the end of the project many of the mentees recognised that they had increased their levels of PA, they were more aware of the benefits of PA and the relationship between PA and their mental health. In addition, mentees reported feeling more confident and were more confident in forming social relationships. Peer mentors reported developing many leadership skills during the project. These included improved communication, confidence, empathy for others, relationship building and improved self-awareness. The paper aims to discuss these issues. Design/methodology/approach – Qualitative data were primarily collected from nine case study schools. Each visit included interviews with peer mentors, mentees and the Wellbeing Champion. Findings – Mentees developed improved social confidence and were generally more positive after completing the intervention. Mentors developed leadership skills and greater empathy for their peers. Originality/value – There is limited research on school-based PA interventions using peer mentoring to improve students’ mental healt

    Smart patch for structural health monitoring of composite repair

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    The bondline integrity of a repair patch to the parent composite laminate is considered the most important factor in the repair design. A smart repair patch is proposed here to allow for real-time ultrasonic guided wave monitoring of repaired composites. A diagnostic film with lead zirconate titanate (PZT) transducers and inkjet-printed wires is embedded into the repair patch using a cut-out method. The electro-mechanical impedance (EMI) method is used to verify the integrity of the embedded PZT transducers. The performance of the smart repair patch is assessed on the external panel with artificial bondline delamination and surface-mounted artificial damage. The damage index correlation coefficient and delay-and-sum (DAS) algorithm are used for damage detection and localization. The results show that the developed repair patch can successfully detect and locate damages

    Awareness of Rational Medication Use and Antibiotic Self- Medication Practices among Undergraduate Students in a University in Sri Lanka

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    Purpose: To evaluate the practice of self-medication and evaluate the knowledge of rational use of antibiotics among undergraduate students of University of Peradeniya, Sri Lanka.Method: A cross-sectional, recall study was conducted among the university student population who practice self-medication in the study location. Stratified, random sampling technique was used to distribute 246 questionnaires in eight faculties of the institution. The response rate was 71%, and 175 completed questionnaires were analyzed to determine significant differences and correlation with different variables.Results: A majority of the study sample were females (54%), aged 23 - 25 years (46.9%). The most frequently used antibiotic was amoxicillin (95.4%). Common cold with fever was the disease condition treated by a large majority (84.9%). Knowledge on dose, frequency, duration and side-effects of antibiotics among students was moderate, with a mean value of 58.3%. There was a significant difference in knowledge on antibiotics between health science and non-health science students although no significant difference was observed in knowledge with respect to gender, academic year and family income.Conclusion: Antibiotic consumption was associated with students’ academic background. This study highlights the need for interventions to assure rational use of antibiotics.Keywords: Antibiotics, Self-medication, Rational use, Undergraduate students, Awarenes

    Spontaneous Achilles tendon rupture in alkaptonuria

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    Spontaneous Achilles tendon ruptures are uncommon. We present a 46-year-old man with spontaneous Achilles tendon rupture due to ochronosis. To our knowledge, this has not been previously reported in Sudan literature. The tendon of the reported patient healed well after debridement and primary repairs

    An innovative diagnostic film for structural health monitoring of metallic and composite structures

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    A novel lightweight diagnostic film with sensors/actuators and a multiple-path wiring option using inkjet printing was developed. The diagnostic film allows for systematic, accurate, and repeatable sensor placement. Furthermore, the film is highly flexible and adaptable for placement on complex configurations. The film can be attached to the surface of the structure through a uniform secondary boundary procedure or embedded within the composite layup during curing. The surface-mounted film can simply be peeled off for repair or replacement without scratching or damaging the part. The film offers significant weight reduction compared to other available technologies. A set of extreme temperature, altitude, and vibration environment test profiles were carried out following the Radio Technical Commission for Aeronautics (RTCA) DO-160 document to assess the durability and performance of the diagnostic film for onboard application. The diagnostic film was shown to be durable and reliable in withstanding the variable operational and harsh environmental conditions of tests representing the conditions of regional aircraf
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