Experimental investigation on the impact of connate water salinity on dispersion coefficient in consolidated rocks cores during enhanced gas recovery by CO2 injection

Connate water salinity is a vital property of the reservoir and its influence on the displacement efficiency cannot be overemphasised. Despite the numerous analytical literatures on the dispersion behaviour of CO2 in CH4 at different parametric conditions, studies have so far been limited to systematic effects of the process while parameters such as connate water salinity of the reservoir has not been given much attention and this could redefine the CO2-CH4 interactions in the reservoir. This study aims to experimentally determine the effect of connate water salinity on the dispersion coefficient in consolidated porous media under reservoir conditions. A laboratory core flooding experiment depicting the detailed process of the CO2-CH4 displacement using Grey Berea sandstone core sample at a temperature of 50°C and at a pressure of 1300 psig was carried out to determine the optimum injection rate, from 0.2-0.5 ml/min, for the experimentation based on dispersion coefficients and methane recovery in the horizontal orientation. This was established to be 0.3 ml/min. At the same conditions, the effects of connate water saturation of 10% and a salinity of 0 (distilled water), 5, and 10% wt. with a CO2 injection rate of 0.3 ml/min on the dispersion coefficients was investigated. The results from the core flooding process indicated that the dispersion coefficient decreases with increasing salinity, hence the higher the density of the immobile phase (connate water) the lower the dispersion of CO2 into CH4. This is a significant finding given that the inclusion of the connate water and its salinity have an effect on the mixing of the gases in the core sample and should be given importance and included during simulation studies for field scale applications of Enhanced Gas Recovery (EGR). This is the first experimental investigation into the relationship between the connate water salinity and the dispersion coefficient in consolidated porous media. Keywords: Enhanced Gas Recovery; Dispersion Coefficient; Connate water Salinity; CO2 sequestratio

Costs analysis of a population level rabies control programme in Tamil Nadu, India

The study aimed to determine costs to the state government of implementing different interventions for controlling rabies among the entire human and animal populations of Tamil Nadu. This built upon an earlier assessment of Tamil Nadu’s efforts to control rabies. Anti-rabies vaccines were made available at all health facilities. Costs were estimated for five different combinations of animal and human interventions using an activity-based costing approach from the provider perspective. Disease and population data were sourced from the state surveillance data, human census and livestock census. Program costs were extrapolated from official documents. All capital costs were depreciated to estimate annualized costs. All costs were inflated to 2012 Rupees. Sensitivity analysis was conducted across all major cost centres to assess their relative impact on program costs. It was found that the annual costs of providing Anti-rabies vaccine alone and in combination with Immunoglobulins was \$0.7 million (Rs 36 million) and \$2.2 million (Rs 119 million), respectively. For animal sector interventions, the annualised costs of rolling out surgical sterilisation-immunization, injectable immunization and oral immunizations were estimated to be \$ 44 million (Rs 2,350 million), \$23 million (Rs 1,230 million) and \$ 11 million (Rs 590 million), respectively. Dog bite incidence, health systems coverage and cost of rabies biologicals were found to be important drivers of costs for human interventions. For the animal sector interventions, the size of dog catching team, dog population and vaccine costs were found to be driving the costs. Rabies control in Tamil Nadu seems a costly proposition the way it is currently structured. Policy makers in Tamil Nadu and other similar settings should consider the long-term financial sustainability before embarking upon a state or nation-wide rabies control programme

GREEN SYNTHESIS OF PLANT-MEDIATED METAL NANOPARTICLES: THE ROLE OF POLYPHENOLS

The use of metal nanoparticles (MNPs) in various fields is increasing day-by-day leading to a genuine concern about the issues related to their environmental and biological safety. The major approaches for the synthesis of NPs include physical and chemical methods which are expensive and hazardous to health in addition to being toxic to the environment. This review highlights the potential of plant extracts to carry out the synthesis of MNPs with a special emphasis on the role of flavonoids in nanosynthesis. This green and clean approach have been actively utilized in recent years as an alternative to conventional hazardous approaches. It has proved as cost-effective, non-toxic, less time and labor consuming, efficient, and eco-friendly method for the synthesis of MNPs with specific biological actions. This review also focuses on the role of polyphenols, including the flavonoids as bioreductants of metal salts for the synthesis of NPs along with their biomedical applications. Various examples of the MNPs, along with their biological actions, have also been summarized

Analysis of electrodeposited CdTe thin films grown using cadmium chloride precursor for applications in solar cells

Deposition of cadmium telluride (CdTe) from cadmium chloride (CdCl2) and tellurium oxide has been achieved by electroplating technique using two-electrode configuration. Cyclic voltammetry shows that near-stoichiometric CdTe is achievable between 1330 and 1400 mV deposition voltage range. The layers grown were characterised using X-ray diffraction (XRD), UV–Visible spectrophotometry, scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDX), photoelectrochemical (PEC) cell and DC conductivity measurements. The XRD shows that the electrodeposited CdTe layer is polycrystalline in nature. The UV–Visible spectrophotometry shows that the bandgap of both as-deposited and heat-treated CdTe films are in the range of (1.44–1.46) eV. The SEM shows grain growth after CdCl2 treatment, while, the EDX shows the effect of growth voltage on the atomic composition of CdTe layers. The PEC results show that both p- and n-type CdTe can be electrodeposited and the DC conductivity reveals that the high resistivity is at the inversion growth voltage (Vi) for the as-deposited and CdCl2 treated layers

Real-life use of vitamin D_3-fortified bread and milk during a winter season: the effects of CYP2R1 and GC genes on 25-hydroxyvitamin D concentrations in Danish families, the VitmaD study.

Common genetic variants rs10741657 and rs10766197 in CYP2R1 and rs4588 and rs842999 in GC and a combined genetic risk score (GRS) of these four variants influence late summer 25-hydroxyvitamin D (25(OH)D) concentrations. The objectives were to identify those who are most at risk of developing low vitamin D status during winter and to assess whether vitamin D(3)-fortified bread and milk will increase 25(OH)D concentrations in those with genetically determined low 25(OH)D concentrations at late summer. We used data from the VitmaD study. Participants were allocated to either vitamin D(3)-fortified bread and milk or non-fortified bread and milk during winter. In the fortification group, CYP2R1 (rs10741657) and GC (rs4588 and rs842999) were statistically significantly associated with winter 25(OH)D concentrations and CYP2R1 (rs10766197) was borderline significant. There was a negative linear trend between 25(OH)D concentrations and carriage of 0–8 risk alleles (p < 0.0001). No association was found for the control group (p = 0.1428). There was a significant positive linear relationship between different quintiles of total vitamin D intake and the increase in 25(OH)D concentrations among carriers of 0–2 (p = 0.0012), 3 (p = 0.0001), 4 (p = 0.0118) or 5 (p = 0.0029) risk alleles, but not among carriers of 6–8 risk alleles (p = 0.1051). Carriers of a high GRS were more prone to be vitamin D deficient compared to carriers of a low GRS. Furthermore, rs4588-AA carriers have a low but very stable 25(OH)D concentration, and interestingly, also low PTH level. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12263-014-0413-7) contains supplementary material, which is available to authorized users

A sensorised surgical glove to improve training and detection of obstetric anal sphincter injury: A preclinical study on a pig model

OBJECTIVE: To create a sensorised surgical glove that can accurately identify obstetric anal sphincter injury to facilitate timely repair, reduce complications and aid training. DESIGN: Proof-of-concept. SETTING: Laboratory. SAMPLE: Pig models. METHODS: Flexible triboelectric pressure/force sensors were mounted onto the fingertips of a routine surgical glove. The sensors produce a current when rubbed on materials of different characteristics which can be analysed. A per rectum examination was performed on the intact sphincter of pig cadavers, analogous to routine examination for obstetric anal sphincter injuries postpartum. An anal sphincter defect was created by cutting through the vaginal mucosa and into the external anal sphincter using a scalpel. The sphincter was then re-examined. Data and signals were interpreted. MAIN OUTCOME MEASURES: Sensitivity and specificity of the glove in detecting anal sphincter injury. RESULTS: In all, 200 examinations were performed. The sensors detected anal sphincter injuries in a pig model with sensitivities between 98% and 100% and a specificity of 100%. The current produced when examining an intact sphincter and sphincter with a defect was significantly different (p < 0.001). CONCLUSION: In this preliminary study, the sensorised glove accurately detected anal sphincter injury in a pig model. Future plans include its clinical translation, starting with an in-human study on postpartum women, to determine whether it can accurately detect different types of obstetric anal sphincter injury in vivo

Canine trypanosomosis: a case report

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗTrypanosomosis is a haemoprotozoan infection affecting a broad range of wild and domestic animals including dogs. Infected dogs may die within 2-4 weeks in the acute and fatal form of the disease. A dog was presented with the complaint of anorexia, persistent recumbency and loss of body weight which lasted for few days. On clinical examination, the affected dog revealed rise in temperature (105°F), lachrimation, anaemia, unilateral corneal opacity, swelling of throat, enlargement of lymph nodes and severe loss of bodily condition. Wet smear, thin blood smear and hematological parameters were observed. Motile trypanosomes were found in wet smear, while trypanosomes with a characteristic flagellum, kinetoplast and undulating membrane were present outside the red blood cells in the thin smear. The dog was successfully recovered with a single dose of diminazene aceturate. This report may provide a way forward to establish effective and safe therapeutic protocols for the control of canine trypanosomosis