Chronic kidney disease and coenzyme Q10 supplementation

Among the potential causes of chronic kidney disease (CKD), mitochondrial respiratory chain (MRC) dysfunction, oxidative stress and inflammation have been implicated as contributor factors to the pathogenesis of this disorder. It is thought that CoQ10 supplementation may offer some therapeutic potential in the treatment of patients with CKD, since CoQ10 has a key role in normal MRC function, as well as having antioxidant and anti-inflammatory action. This article will outline the current knowledge on the use of CoQ10 in the treatment of CK

Measurement of the top quark pair cross section with ATLAS in pp collisions at root s=7 TeV using final states with an electron or a muon and a hadronically decaying tau lepton

A measurement of the cross section of top quark pair production in proton-proton collisions recorded with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 7 TeV is reported. The data sample used corresponds to an integrated luminosity of 2.05 fb(-1). Events with an isolated electron or muon and a tau lePton decaying hadronically are used. In addition, a large missing transverse momentum and two or more energetic jets are required. At least one of the jets must be identified as originating from a b quark. The measured cross section, sigma(t (t) over bar) = 186 +/- 13 (stat.) +/- 20 (syst.) +/- 7 (lumi.) pb, is in good agreement with the Standard Model prediction. (C) 2012 CERN. Published by Elsevier B.V. All rights reserved