16 research outputs found
Spatial Thinking Ability Acquisition Through Geospatial Technologies for Lifelong Learning
No full textRelationship between gastric pouch and weight loss after laparoscopic sleeve gastrectomy
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Relationship between dementia and gut microbiome-associated metabolites: a cross-sectional study in Japan
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Is it smart to read on your phone? The impact of reading format and culture on the continued influence of misinformation
No full textHuman mesenchymal stem cells in spheroids improve fertility in model animals with damaged endometrium
No full textTransgenic and knockout mice in the study of neurodegenerative diseases.
Full text linkAccurate animal models are essential for detailed analysis of the mechanisms underlying human neurodegenerative diseases. In addition, they can offer useful paradigms for the development and evaluation of new therapeutic strategies. We review the most popular techniques for modification of the mammalian genome in vivo, and provide a critical evaluation of the available transgenic mouse models for several neurological conditions of humans, including prion diseases, human retroviral diseases, Alzheimer's disease, and motor neuron diseases
