995 research outputs found
A numerical approach for liquefaction potential definition
Liquefaction phenomenon in saturated granular soil is not that frequent as amplification cases but can cause
heavy damages on buildings and infrastructures whenever is occurs especially within superficial strata. In fact
the lack of shear resistance of soil due to liquefaction affects mostly shallow foundations and road surfaces. Up
now, several studies have been addressed to overpass the inadequacy of liquefaction safety factor by means of
introducing the liquefaction potential. Nevertheless, the difficulty in (1) defining a scale of damage related to
liquefaction potential values and (2) collecting field data from damages caused prevalently by liquefaction
makes the punctual factor of safety still popular in engineering practice. In this paper a new approach to
liquefaction potential estimation is proposed based on finite element dynamic analyses and on the concept of
“significant volume” according to possible effects suffered by shallow foundations. One-dimensional
simulation of liquefaction occurrence is performed by means of the Pastor-Zienkiewicz constitutive law. Hence
the estimation of liquefaction potential is gained as well as the stress influence factor from Westergaard
solution is calculated
Work-Related Mental Health and Job Performance: Can Mindfulness Help?
Work-related mental health issues such as work-related stress and addiction to work impose a significant health and economic burden to the employee, the employing organization, and the country of work more generally. Interventions that can be empirically shown to improve levels of work-related mental health – especially those with the potential to concurrently improve employee levels of work performance – are of particular interest to occupational stakeholders. One such broad-application interventional approach currently of interest to occupational stakeholders in this respect is mindfulness-based interventions (MBIs). Following a brief explication of the mindfulness construct, this paper critically discusses current research directions in the utilization of mindfulness in workplace settings and assesses its suitability for operationalization as an organization-level work-related mental health intervention. By effecting a perceptual-shift in the mode of responding and relating to sensory and cognitive-affective stimuli, employees that undergo mindfulness training may be able to transfer the locus of control for stress from external work conditions to internal metacognitive and attentional resources. Therefore, MBIs may constitute cost-effective organization-level interventions due to not actually requiring any modifications to human resource management systems and practises. Based on preliminary empirical findings and on the outcomes of MBI studies with clinical populations, it is concluded that MBIs appear to be viable interventional options for organizations wishing to improve the mental health of their employees
Meditation Awareness Training (MAT) for Work-related Wellbeing and Job Performance: A Randomised Controlled Trial
Due to its potential to concurrently improve work-related wellbeing (WRW) and job performance, occupational stakeholders are becoming increasingly interested in the applications of meditation. The present study conducted the first randomized controlled trial to assess the effects of meditation on outcomes relating to both WRW and job performance. Office-based middle-hierarchy managers (n = 152) received an eight-week meditation intervention (Meditation Awareness Training; MAT) or an active control intervention. MAT participants demonstrated significant and sustainable improvements (with strong effect sizes) over control-group participants in levels of work-related stress, job satisfaction, psychological distress, and employer-rated job performance. There are a number of novel implications: (i) meditation can effectuate a perceptual shift in how employees experience their work and psychological environment and may thus constitute a cost-effective WRW intervention, (ii) meditation-based (i.e., present-moment-focussed) working styles may be more effective than goal-based (i.e., future-orientated) working styles, and (iii) meditation may reduce the separation made by employees between their own interests and those of the organizations they work for
Simplified numerical models to simulate hollow monopile wind turbine foundations
The majority of wind turbine foundations consist of hollow monopiles inserted in the soil, requiring high computational effort to be numerically simulated. Alternative simplified models are very often employed instead. Three-dimensional solid models, in which the hollow structure and pile are substituted by solid cylinders with equivalent properties, are the most extended simplifications. Very few 2D models can be found in the literature due to the challenge of finding suitable equivalent properties and loads to fully represent the 3D nature of the problem. So far, very limited attention has been devoted to the accuracy of both 3D and 2D simplified models under dynamic and even static actions. Thus, in this paper, simplified 3D and 2D solid models are proposed and justified. An elasto-plastic constitutive model with accumulative degradation is used to simulate the soil behaviour, and frictional contact elements are implemented between the soil and pile to model their interaction. These simplified approaches are compared with the full 3D hollow model, under static and cyclic loads. The results demonstrate that the proposed simplified approaches are a reasonable alternative to the 3D hollow model, which allows researchers and designers to drastically reduce the computational effort in the simulations under long term conditions
Effect of polymer emulsion of the bearing capacity of Aeolian sand under extreme confinement conditions
An experimental investigation, aimed at evaluating the improvement of Aeolian sand (from Saudi Arabia) when treated with low dosages of a vinyl acrylic (a polymer emulsion), is reported in this paper. Special attention is devoted to the influence of the lateral confinement, particularly in terms of compaction and bearing capacity (represented by CBR), for which a modification of the standard test has been developed trying to simulate extreme confinement conditions. Experimental results demonstrate that this kind of chemical stabilizers can be considered as a suitable alternative for these materials. The main modifications induced in the sand by this additive are highlighted and quantified by means of the modification achieved for different geotechnical properties as well as Scanning Electron Microscope (SEM) and Energy-Dispersive X-Ray Spectroscopy (EDX) analyses
Functional characterisation of the methionine sulfoxide reductase repertoire in Trypanosoma brucei
We thank Guy Hanke (QMUL) for their critical review of this manuscript. We acknowledge the members of the T. brucei genome (http://tritrypdb.org/tritrypdb/) and TrypTag (http://tryptag.org) projects for sequence and localisation data, respectively. A component of this work was supported by grants from ANPCyT (PICT-2015-1149; PICT-2014-2103). SAG, and DGA are investigator career members from CONICET. AK was a recipient of a Queen Mary University of London PhD studentshi
Genome-Wide SNP-genotyping array to study the evolution of the human pathogen Vibrio vulnificus Biotype 3
Vibrio vulnificus is an aquatic bacterium and an important human pathogen. Strains Of V. vulnificus are classified into three different biotypes. The newly emerged biotype 3 has been found to be clonal and restricted to Israel. In the family Vibrionaceae , horizontal gene transfer is the main mechanism responsible for the emergence of new pathogen groups. To better understand the evolution of the bacterium, and in particular to trace the evolution of biotype 3, we performed genome-wide SNP genotyping of 254 clinical and environmental V. vulnificus isolates with worldwide distribution recovered over a 30-year period, representing all phylogeny groups. A custom single-nucleotide polymorphism (SNP) array implemented on the Illumina GoldenGate platform was developed based on 570 SNPs randomly distributed throughout the genome. In general, the genotyping results divided the V. vulnificus species into three main phylogenetic lineages and an additional subgroup, clade B, consisting of environmental and clinical isolates from Israel. Data analysis suggested that 69% of biotype 3 SNPs are similar to SNPs from clade B, indicating that biotype 3 and clade B have a common ancestor. The rest of the biotype 3 SNPs were scattered along the biotype 3 genome, probably representing multiple chromosomal segments that may have been horizontally inserted into the clade B recipient core genome from other phylogroups or bacterial species sharing the same ecological niche. Results emphasize the continuous evolution of V. vulnificus and support the emergence of new pathogenic groups within this species as a recurrent phenomenon. Our findings contribute to a broader understanding of the evolution of this human pathogen
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Safeguarding pollinators and their values to human well-being
Wild and managed pollinators provide a wide range of benefits to society in terms of contributions to food security, farmer
and beekeeper livelihoods, social and cultural values, as well as the maintenance of wider biodiversity and ecosystem
stability. Pollinators face numerous threats, including changes in land-use and management intensity, climate change,
pesticides and genetically modified crops, pollinator management and pathogens, and invasive alien species. There are
well-documented declines in some wild and managed pollinators in several regions of the world. However, many effective
policy and management responses can be implemented to safeguard pollinators and sustain pollination services
Bioaccumulation and ecotoxicity of carbon nanotubes
Carbon nanotubes (CNT) have numerous industrial applications and may be released to the environment. In the aquatic environment, pristine or functionalized CNT have different dispersion behavior, potentially leading to different risks of exposure along the water column. Data included in this review indicate that CNT do not cross biological barriers readily. When internalized, only a minimal fraction of CNT translocate into organism body compartments. The reported CNT toxicity depends on exposure conditions, model organism, CNT-type, dispersion state and concentration. In the ecotoxicological tests, the aquatic organisms were generally found to be more sensitive than terrestrial organisms. Invertebrates were more sensitive than vertebrates. Single-walled CNT were found to be more toxic than double-/multi-walled CNT. Generally, the effect concentrations documented in literature were above current modeled average environmental concentrations. Measurement data are needed for estimation of environmental no-effect concentrations. Future studies with benchmark materials are needed to generate comparable results. Studies have to include better characterization of the starting materials, of the dispersions and of the biological fate, to obtain better knowledge of the exposure/effect relationships
Wetlands for wastewater treatment and subsequent recycling of treated effluent : a review
Due to water scarcity challenges around the world, it is essential to think about non-conventional water resources to address the increased demand in clean freshwater. Environmental and public health problems may result from insufficient provision of sanitation and wastewater disposal facilities. Because of this, wastewater treatment and recycling methods will be vital to provide sufficient freshwater in the coming decades, since water resources are limited and more than 70% of water are consumed for irrigation purposes. Therefore, the application of treated wastewater for agricultural irrigation has much potential, especially when incorporating the reuse of nutrients like nitrogen and phosphorous, which are essential for plant production. Among the current treatment technologies applied in urban wastewater reuse for irrigation, wetlands were concluded to be the one of the most suitable ones in terms of pollutant removal and have advantages due to both low maintenance costs and required energy. Wetland behavior and efficiency concerning wastewater treatment is mainly linked to macrophyte composition, substrate, hydrology, surface loading rate, influent feeding mode, microorganism availability, and temperature. Constructed wetlands are very effective in removing organics and suspended solids, whereas the removal of nitrogen is relatively low, but could be improved by using a combination of various types of constructed wetlands meeting the irrigation reuse standards. The removal of phosphorus is usually low, unless special media with high sorption capacity are used. Pathogen removal from wetland effluent to meet irrigation reuse standards is a challenge unless supplementary lagoons or hybrid wetland systems are used
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