4,759 research outputs found
Clinical guidelines for the management of cutaneous leishmaniasis in British military personnel.
Complete resummation of chirally-enhanced loop-effects in the MSSM with non-minimal sources of flavor-violation
In this article we present the complete resummation of the leading
chirally-enhanced corrections stemming from gluino-squark, chargino-sfermion
and neutralino-sfermion loops in the MSSM with non-minimal sources of
flavor-violation. We compute the finite renormalization of fermion masses and
the CKM matrix induced by chirality-flipping self-energies. In the decoupling
limit Msusy>>v, which is an excellent approximation to the full theory, we give
analytic results for the effective gaugino(higgsino)-fermion-sfermion and the
Higgs-fermion-fermion vertices. Using these vertices as effective Feynman
rules, all leading chirally-enhanced corrections can consistently be included
into perturbative calculations of Feynman amplitudes. We also give a
generalized parametrization for the bare CKM matrix which extends the classic
Wolfenstein parametrization to the case of complex parameters lambda and A.Comment: 31 pages, 3 figures; typos correcte
A 125 GeV SM-like Higgs in the MSSM and the rate
We consider the possibility of a Standard Model (SM)-like Higgs in the
context of the Minimal Supersymmetric Standard Model (MSSM), with a mass of
about 125 GeV and with a production times decay rate into two photons which is
similar or somewhat larger than the SM one. The relatively large value of the
SM-like Higgs mass demands stops in the several hundred GeV mass range with
somewhat large mixing, or a large hierarchy between the two stop masses in the
case that one of the two stops is light. We find that, in general, if the
heaviest stop mass is smaller than a few TeV, the rate of gluon fusion
production of Higgs bosons decaying into two photons tends to be somewhat
suppressed with respect to the SM one in this region of parameters. However, we
show that an enhancement of the photon decay rate may be obtained for light
third generation sleptons with large mixing, which can be naturally obtained
for large values of and sizable values of the Higgsino mass
parameter.Comment: 14 pages, 4 figures. Corrected small typos and added reference
Breast cancer histologic grading using digital microscopy: concordance and outcome association
Aims: Virtual microscopy utilising digital whole slide imaging (WSI) is increasingly used in breast pathology. Histologic grade is one of the strongest prognostic factors in breast cancer (BC). This study aims at investigating the agreement between BC grading using traditional light microscopy (LM) and digital whole slide imaging (WSI) with consideration of reproducibility and impact on outcome prediction.
Methods: A large (n=1675) well-characterised cohort of BC originally graded by LM was re-graded using WSI. Two separate virtual-based grading sessions (V1 and V2) were performed with a three months washout period. Outcome was assessed using breast cancer specific and distant metastasis free survival.
Results: The concordance between LM grading and WSI was strong (LM/SWI Cramer’s V: V1=0.576, and V2=0.579). The agreement regarding grade components was as follows: Tubule formation=0.538, Pleomorphism=0.422 and Mitosis=0.514. Greatest discordance was observed between adjacent grades whereas high/low grade discordance was uncommon (1.5%). The intra-observer agreement for the two WSI sessions was substantial for grade (V1/V2 Cramer’s V=0.676; kappa=0.648) and grade components (Cramer’s V T=0.628, P=0.573 and M=0.580). Grading using both platforms showed strong association with outcome (All p-value <0.001). Although mitotic scores assessed using both platforms were strongly associated with outcome, WSI tends to underestimate mitotic counts.
Conclusions: Virtual microscopy is a reliable and reproducible method for assessing BC histologic grade. Regardless of the observer or assessment platform, histologic grade is a significant predictor of outcome. Continuing advances in imaging technology could potentially provide improved performance of WSI BC grading and in particular mitotic count assessment
Phenomenology and Cosmology of an Electroweak Pseudo-Dilaton and Electroweak Baryons
In many strongly-interacting models of electroweak symmetry breaking the
lowest-lying observable particle is a pseudo-Goldstone boson of approximate
scale symmetry, the pseudo-dilaton. Its interactions with Standard Model
particles can be described using a low-energy effective nonlinear chiral
Lagrangian supplemented by terms that restore approximate scale symmetry,
yielding couplings of the pseudo-dilaton that differ from those of a Standard
Model Higgs boson by fixed factors. We review the experimental constraints on
such a pseudo-dilaton in light of new data from the LHC and elsewhere. The
effective nonlinear chiral Lagrangian has Skyrmion solutions that may be
identified with the `electroweak baryons' of the underlying
strongly-interacting theory, whose nature may be revealed by the properties of
the Skyrmions. We discuss the finite-temperature electroweak phase transition
in the low-energy effective theory, finding that the possibility of a
first-order electroweak phase transition is resurrected. We discuss the
evolution of the Universe during this transition and derive an
order-of-magnitude lower limit on the abundance of electroweak baryons in the
absence of a cosmological asymmetry, which suggests that such an asymmetry
would be necessary if the electroweak baryons are to provide the cosmological
density of dark matter. We revisit estimates of the corresponding
spin-independent dark matter scattering cross section, with a view to direct
detection experiments.Comment: 34 pages, 4 figures, additional references adde
Some remarks on a new exotic spacetime for time travel by free fall
This work is essentially a review of a new spacetime model with closed causal
curves, recently presented in another paper (Class. Quantum Grav.
\textbf{35}(16) (2018), 165003). The spacetime at issue is topologically
trivial, free of curvature singularities, and even time and space orientable.
Besides summarizing previous results on causal geodesics, tidal accelerations
and violations of the energy conditions, here redshift/blueshift effects and
the Hawking-Ellis classification of the stress-energy tensor are examined.Comment: 17 pages, 9 figures. Submitted as a contribution to the proceedings
of "DOMOSCHOOL - International Alpine School of Mathematics and Physics,
Domodossola 2018". Possible text overlaps with my previous work
arXiv:1803.08214, of which this is essentially a review. Additional results
concerning redshift/blueshift effects and the classification of the
stress-energy tensor are presented her
Search for the Elusive Higgs Boson Using Jet Structure at LHC
We consider the production of a light non-standard model Higgs boson of order
100~\GEV with an associated boson at CERN Large Hadron Collider. We focus
on an interesting scenario that, the Higgs boson decays predominately into two
light scalars with mass of few GeV which sequently decay into four
gluons, i.e. . Since is much lighter than the Higgs
boson, it will be highly boosted and its decay products, the two gluons, will
move close to each other, resulting in a single jet for decay in the
detector. By using electromagnetic calorimeter-based and jet substructure
analyses, we show in two cases of different masses that it is quite
promising to extract the signal of Higgs boson out of large QCD background.Comment: 20 pages, 7 figure
Flavour physics constraints in the BMSSM
We study the implications of the presence of the two leading-order,
non-renormalizable operators in the Higgs sector of the MSSM to flavour physics
observables. We identify the constraints of flavour physics on the parameters
of the BMSSM when we: a) focus on a region of parameters for which electroweak
baryogenesis is feasible, b) use a CMSSM-like parametrization, and c) consider
the case of a generic NUHM-type model. We find significant differences as
compared to the standard MSSM case.Comment: 22 pages, 7 figure
Neutralino versus axion/axino cold dark matter in the 19 parameter SUGRA model
We calculate the relic abundance of thermally produced neutralino cold dark
matter in the general 19 parameter supergravity (SUGRA-19) model. A scan over
GUT scale parameters reveals that models with a bino-like neutralino typically
give rise to a dark matter density \Omega_{\tz_1}h^2\sim 1-1000, i.e. between 1
and 4 orders of magnitude higher than the measured value. Models with higgsino
or wino cold dark matter can yield the correct relic density, but mainly for
neutralino masses around 700-1300 GeV. Models with mixed bino-wino or
bino-higgsino CDM, or models with dominant co-annihilation or A-resonance
annihilation can yield the correct abundance, but such cases are extremely hard
to generate using a general scan over GUT scale parameters; this is indicative
of high fine-tuning of the relic abundance in these cases. Requiring that
m_{\tz_1}\alt 500 GeV (as a rough naturalness requirement) gives rise to a
minimal probably dip in parameter space at the measured CDM abundance. For
comparison, we also scan over mSUGRA space with four free parameters. Finally,
we investigate the Peccei-Quinn augmented MSSM with mixed axion/axino cold dark
matter. In this case, the relic abundance agrees more naturally with the
measured value. In light of our cumulative results, we conclude that future
axion searches should probe much more broadly in axion mass, and deeper into
the axion coupling.Comment: 23 pages including 17 .eps figure
Higgs boson enhancement effects on squark-pair production at the LHC
We study the Higgs boson effects on third-generation squark-pair production
in proton-proton collision at the CERN Large Hadron Collider (LHC), including
\Stop \Stop^*, \Stop\Sbot^*, and \Sbot \Sbot^*. We found that substantial
enhancement can be obtained through s-channel exchanges of Higgs bosons at
large , at which the enhancement mainly comes from , , and initial states. We compute the complete set of electroweak
(EW) contributions to all production channels. This completes previous
computations in the literature. We found that the EW contributions can be
significant and can reach up to 25% in more general scenarios and at the
resonance of the heavy Higgs boson. The size of Higgs enhancement is comparable
or even higher than the PDF uncertainties and so must be included in any
reliable analysis. A full analytical computation of all the EW contributions is
presented.Comment: 23 pages, 7 figures, 1 tabl
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