82 research outputs found
Isolation of Halophilic Bacteria from Inland Petroleum- Producing Wells
The goals of this study were to isolate microorganisms from oil
well-produced water, identify the microorganisms, and test the microorganisms’ salt
tolerance. Saltwater collected from two well locations producing from different zones in
Jones County, Texas, was spread onto Mannitol Salt Agar (MSA). Isolates showed a 16S rDNA
gene sequence identity of 99% with Idiomarina baltica and Marinobacter persicus. Salt
tolerance assays indicated an optimal growth concentration of 10-12.5% NaCl for the
Idiomarina isolate and a decrease in growth beyond 5% NaCl for the Marinobacter isolate. In
conclusion, organisms that are phylogenetically similar to marine microorganisms are present
in oil well environments, and have variable salt tolerances, which may prove useful in
microbialmediated hydrocarbon bioremediation of high salinity environments
Specific Cognitive Deficits in ADHD: A Diagnostic Concern in Differential Diagnosis
We present a critical account of existing tools used to diagnose children with Attention Deficit Hyperactivity Disorder and to make a case for the assessment of cognitive impairments as a part of diagnostic system. Surveys have shown that clinicians rely almost entirely upon subjective reports or their own clinical judgment when arriving at diagnostic decisions relating to this prevalent disorder. While information from parents and teachers should always be carefully considered, they are often influenced by a host of emotional and perceptual factors. It increases the possibility for misdiagnosis of a condition like ADHD. Recent experimental literature on ADHD has identified unique underlying cognitive dysfunction, specific to ADHD. Therefore, we propose that there is a need to incorporate information on cognitive mechanisms underlying ADHD and inculcate such information in the diagnostic system, which will provide a more sensitive as well as specific tool in differential diagnosis of ADHD
Emotional well-being in children and adolescents treated with atomoxetine for attention-deficit/hyperactivity disorder: Findings from a patient, parent and physician perspective using items from the pediatric adverse event rating scale (PAERS)
<p>Abstract</p> <p>Background</p> <p>The objective of this analysis was to measure changes in items on the Pediatric Adverse Event Rating Scale (PAERS) that relate to emotional well-being of children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) during treatment with atomoxetine for up to 24 weeks from the perspective of the patient, the parent, and the physician.</p> <p>Methods</p> <p>Patients aged 6–17 years with ADHD were treated with atomoxetine (target dose 1.2 mg/kg/day). In the two studies on which this secondary analysis is based the PAERS was used to assess the tolerability of atomoxetine in children and adolescents. This scale has a total of 48 items. The ten items that reflect emotional well-being were selected to measure changes over time from a patient, parent, and physician perspective.</p> <p>Results</p> <p>421 patients were treated with atomoxetine. 355 patients completed the 8-week treatment period, and 260 patients completed the 24-week treatment period. The ten items that reflect emotional well-being were grouped in five dimensions: depressed mood, self-harm, irritability/agitation, drowsiness, and euphoria. The scores of these dimensions decreased over time, both from a patient as well as from a parent and physician perspective. Only the dimension self-harm was extremely low at baseline and stayed low over time. The mean scores for the ten items depended on the rater perspective.</p> <p>Conclusion</p> <p>The emotional well-being of children and adolescents with ADHD improved in terms of depressed mood, irritability/agitation, drowsiness, and euphoria during treatment with atomoxetine for up to 24 weeks.</p
Neuropsychological Heterogeneity in Preschool ADHD: Investigating the Interplay between Cognitive, Affective and Motivation-Based Forms of Regulation
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