A Prospective Study to Compare the Effect of Ultrasonography Guided versus Anatomical Landmark-based Triamcinolone Injection in the Treatment of De Quervain's Tenosynovitis

Introduction: De Quervain's tenosynovitis (DQT) is a stenosing tenosynovitis of the first extensor compartment of the wrist affecting abductor pollicis longus and extensor pollicis brevis tendons, leading to the narrowing of the fibro-osseous canal, causing radial side wrist pain, decreased thumb and wrist movement culminating in functional impairment of hand. The treatment options for DQT include conservative, minimally invasive procedures and surgery. Minimally invasive procedure, like intra-sheath corticosteroid (CST) injections is a preferred treatment option and ultrasonography (USG) guidance has improved injection accuracy. Role of USG guidance is not yet fully proven in showing clinical improvement and decreasing steroid-associated injection site skin hypopig-mentation. This study aimed to evaluate the role of USG in the clinical improvement and reducing chances of steroid-associated skin hypopigmentation following USG-guided intra-sheath CST injections in comparison to anatomical landmark-based (ALB) technique, in the first extensor compartment of the wrist in DQT. Methodology: A single blind prospective study was done on 83 patients of DQT. Patients were randomized into ultrasonography guided group and anatomical landmark based group according to the injection technique used. A single dose of 1 ml Triamcinolone (40 mg/ml) and 1 ml of 2% Lignocaine was used for injection and patients were followed after 4 weeks and 12 weeks of injection. The visual analog scale (VAS) for pain, patient-rated wrist evaluation (PRWE) score, symptom improvement rate, recurrence rate, steroid-associated injection site skin hypo-pigmentation, and delayed injection site skin hypopigmentation were used for outcome measures. Results: After 4 and 12 weeks, VAS and PRWE scores significantly improved in both groups (p value0.05). The symptom improvement rate at 12 weeks (81.58% in USG versus 57.5% in ALB) was.

A Prospective Study to Compare the Effect of Ultrasonography Guided versus Anatomical Landmark-based Triamcinolone Injection in the Treatment of De Quervains Tenosynovitis

Introduction: De Quervain's tenosynovitis (DQT) is a stenosing tenosynovitis of the first extensor compartment of the wrist affecting abductor pollicis longus and extensor pollicis brevis tendons, leading to the narrowing of the fibro-osseous canal, causing radial side wrist pain, decreased thumb and wrist movement culminating in unctional impairment of hand. The treatment options for DQT include conservative, minimally invasive procedures and surgery. Minimally invasive procedure, like intra-sheath corticosteroid (CST) injections is a preferred treatment option and ultrasonography (USG) guidance has improved injection accuracy. Role of USG guidance is not yet fully proven in showing clinical improvement and decreasing steroid-associated injection site skin hypopigmentation. This study aimed to evaluate the role of USG in the clinical improvement and reducing chances of steroid-associated skin hypopigmentation following USG-guided intra-sheath CST injections in comparison to anatomical landmark-based (ALB) technique, in the first extensor compartment of the wrist in DQT. Methodology: A single blind prospective study was done on 83 patients of DQT. Patients were randomized into ultrasonography guided group and anatomical landmark based group according to the injection technique used. A single dose of 1 ml Triamcinolone (40 mg/ml) and 1 ml of 2% Lignocaine was used for injection and patients were followed after 4 weeks and 12 weeks of injection. The visual analog scale (VAS) for pain, patient-rated wrist evaluation (PRWE) score, symptom improvement rate, recurrence rate, steroid-associated injection site skin hypo-pigmentation, and delayed injection site skin hypopigmentation were used for outcome measures. Results:....

Online Marketing and Consumer: A Bibliometric Study

The online marketing develops not only in one country but globally. And there is a growth in the research on online marketing as well in the global level. This research aims to provide a global perspective regarding online marketing and consumer research, by identifying annual production, most productive authors, countries, institutions, journals and also Co-cited and bibliographically coupled authors, journals and documents. And to identify the future scope of research in online marketing and consumer. This research analysed 450 documents from the Scopus core collection from 1996 to 2023. The data analysis is conducted using Biblioshiny in R and VOS viewer. Results showed a growing trend in publishing of documents in the field of Analysis. The most productive author is Mackey TK, the most productive journal is Journal of research in interactive marketing. USA is the most productive region and University of California is the most productive Institution. The most important keywords are Online marketing, social media, social media marketing, consumer behaviour, e-commerce and others. The results also presented different networks of authors, documents and journals. Finally analysing the future research areas

Process optimization of saturated steam-assisted texturized plant protein for mimicking cooked chicken breast characteristics

Abstract This study addresses the global demand for sustainable protein alternatives by optimizing the texturization of plant-based proteins using saturated steam technology. The optimization of this process was done using a Central Composite Rotatable Design for key process parameters (e.g., dough processing time, thermal exposure time & temperature) that influence the quality of TPPs. Saturated steam-assisted texturization significantly impacted the acceptability attributes such as texture, color, and sensory preferences of TPPs. Thermal exposure time and temperature were critical in optimizing hardness, chewiness, and overall acceptability. Increased exposure (beyond 30 min and 115 °C) caused protein denaturation, texture softening, and increased browning. The results indicated that moderate thermal exposure time (30 min) and temperature (118 °C) yielded the most desirable texture, color, and sensory acceptance. Finally, TPPs demonstrated superior protein content (39.41%), lower fat (0.50%), and equivalent in-vitro protein quality (0.86) compared to boneless chicken breast, positioning them as a viable, nutritious alternative to traditional meat products

Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats

889-896Public concerns over possible adverse effects of microwave radiation emitted by mobile phones on health are increasing. To evaluate the intensity of oxidative stress, cognitive impairment and inflammation in brain of Fischer rats exposed to microwave radiation, male Fischer-344 rats were exposed to 900 MHz microwave radiation (SAR = 5.953×10-4 W/kg) and 1800 MHz microwave radiation (SAR = 5.835×10-4 W/kg) for 30 days (2 h/day). Significant impairment in cognitive function and induction of oxidative stress in brain tissues of microwave exposed rats were observed in comparison with sham exposed groups. Further, significant increase in level of cytokines (IL-6 and TNF-) was also observed following microwave exposure. Results of the present study indicated that increased oxidative stress due to microwave exposure may contribute to cognitive impairment and inflammation in brain. </span