Applicability of shape parameterizations for giant dipole resonance in warm and rapidly rotating nuclei

We investigate how well the shape parameterizations are applicable for studying the giant dipole resonance (GDR) in nuclei, in the low temperature and/or high spin regime. The shape fluctuations due to thermal effects in the GDR observables are calculated using the actual free energies evaluated at fixed spin and temperature. The results obtained are compared with Landau theory calculations done by parameterizing the free energy. We exemplify that the Landau theory could be inadequate where shell effects are dominating. This discrepancy at low temperatures and high spins are well reflected in GDR observables and hence insists on exact calculations in such cases.Comment: 10 pages, 2 figure

On the origin of trisomy 21 Down syndrome

Background: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability. It is well known that the extra chromosome 21 most often originates from the mother, the incidence increases with maternal age, there may be aberrant maternal chromosome 21 recombination and there is a higher recurrence in young women. In spite of intensive efforts to understand the underlying reason(s) for these characteristics, the origin still remains unknown. We hypothesize that maternal trisomy 21 ovarian mosaicism might provide the major causative factor. Results: We used fluorescence in situ hybridization (FISH) with two chromosome 21-specific probes to determine the copy number of chromosome 21 in ovarian cells from eight female foetuses at gestational age 14–22 weeks. All eight phenotypically normal female foetuses were found to be mosaics, containing ovarian cells with an extra chromosome 21. Trisomy 21 occurred with about the same frequency in cells that had entered meiosis as in pre-meiotic and ovarian mesenchymal stroma cells. Conclusion: We suggest that most normal female foetuses are trisomy 21 ovarian mosaics and the maternal age effect is caused by differential selection of these cells during foetal and postnatal development until ovulation. The exceptional occurrence of high-grade ovarian mosaicism may explain why some women have a child with Down syndrome already at young age as well as the associated increased incidence at subsequent conceptions. We also propose that our findings may explain the aberrant maternal recombination patterns previously found by family linkage analysis

Giant dipole resonance with exact treatment of thermal fluctuations

The shape fluctuations due to thermal effects in the giant dipole resonance (GDR) observables are calculated using the exact free energies evaluated at fixed spin and temperature. The results obtained are compared with Landau theory calculations done by parameterizing the free energy. The Landau theory is found to be insufficient when the shell effects are dominating.Comment: 5 pages, 2 figure

On the structure of subsets of an orderable group with some small doubling properties

The aim of this paper is to present a complete description of the structure of subsets S of an orderable group G satisfying |S^2| = 3|S|-2 and is non-abelian

'Bodily precision': A predictive coding account of individual differences in interoceptive accuracy

Individuals differ in their awareness of afferent information from within their bodies, which is typically assessed by a heartbeat perception measure of ‘interoceptive accuracy’ (IAcc). Neural and behavioural correlates of this trait have been investigated, but a theoretical explanation has yet to be presented. Building on recent models that describe interoception within the free energy/predictive coding framework, this paper applies similar principles to IAcc, proposing that individual differences in IAcc depend on ‘precision’ in interoceptive systems, i.e. the relative weight accorded to ‘prior’ representations and ‘prediction errors’ (that part of incoming interoceptive sensation not accounted for by priors), at various levels within the cortical hierarchy and between modalities. Attention has the effect of optimizing precision both within and between sensory modalities. Our central assumption is that people with high IAcc are able, with attention, to prioritize interoception over other sensory modalities and can thus adjust the relative precision of their interoceptive priors and prediction errors, where appropriate, given their personal history. This characterization explains key findings within the interoception literature; links results previously seen as unrelated or contradictory; and may have important implications for understanding cognitive, behavioural and psychopathological consequences of both high and low interoceptive awareness. This article is part of the themed issue ‘Interoception beyond homeostasis: affect, cognition and mental health’