12,510 research outputs found
Private Rights of Action Under the Investment Company Act
Glucans are polysaccharides integral to many materials and biological functions. Under the umbrella of Biomime, the Swedish Center for Biomimetic Fiber Engineering, this work has aimed to improve basic understanding of the biosynthesis of such glucans. This has been achieved through direct investigation of cellulose structure, and by developing the tools to analyze glucan biosynthesis. Notably we have identified a novel chemical effector of glucan synthesis processes and developed a proteomic toolkit useful for analyzing membrane-bound glycosyltransferases, the enzyme group responsible for glucan biosynthesis. During this work, glucan synthesis has been studied using both Gluconacetobacter and Populus cell suspension cultures. Publication I. Gluconacetobacter cellulose (BC) was used as a base to create a novel and well characterized nano-material with improved mechanical properties. This novel composite of BC and hydroxyethylcellulose (HEC) had improved tensile strength compared to pure BC. Through thorough study utilizing dispersion measurements, electron microscopy, nuclear magnetic resonance and X-ray diffraction it was shown that the improved properties derived from a layer of HEC coating each fibril. Publication II. Bacterial cellulose was labeled in specific positions with 13C (C4 and C6). These samples were analyzed by CP/MAS NMR along with cellulose samples from cotton and Halocynthia sp. For each sample spectral fitting was performed and general properties of crystal allomorph composition and fibril widths were determined. Calculations were also made for water accessible surfaces of the fibrils. The results showed that water accessible C4 surface signals are reflective of the allomorph composition of the sample, along with a distorted signal that derives due to fibril imperfections. Water accessible surface signals from the C6 region are instead derived from rotamer conformations of the C6 hydroxymethyl groupsfrom glucose residues. In Publication III, a high-throughput screen was used to identify an inhibitor of Golgi-derived glycosyltransferase activity, termed chemical A. The structural basis for inhibition was determined and in vitro assays of callose synthesis were performed. The in vitro assays revealed chemical A to also be an activator of callose synthesis. To understand this activation kinetic studies were performed, showing that chemical A is a mixed type of activator, which can bind either the free enzyme or the enzyme-substrate complex. Chemical A has uses in chemical genetics for dissecting processes involving callose synthesis, such as stress response and cell-plate formation. In publication IV, we present an in-house developed platform for proteomics with a distributed processing model. This in-house system has been central to many proteomics tasks, including for those presented in publication V, and is being distributed as the Automated Proteomics Pipeline (APP). In publication V, conditions for enrichment of Detergent-Resistant Microdomains (DRM) have been optimized for Populus trichocarpa cell cultures. The proteins enriched in DRM were identified using mass spectrometry based proteomics, and a functional model for DRM was proposed. This model involves proteins specialized in stress response, including callose synthase, and cell signaling. This further strengthens the arguments for DRMs as sites of specific cellular functions and confirms they play a role in glucan synthesis.QC 20140710</p
Impact of Warped Extra Dimensions on the Dipole Coefficients in Transitions
We calculate the electro- and chromomagnetic dipole coefficients
and in the context of the minimal
Randall-Sundrum (RS) model with a Higgs sector localized on the IR brane using
the five-dimensional (5D) approach, where the coefficients are expressed in
terms of integrals over 5D propagators. Since we keep the full dependence on
the Yukawa matrices, the integral expressions are formally valid to all orders
in . In addition we relate our results to the expressions
obtained in the Kaluza-Klein (KK) decomposed theory and show the consistency in
both pictures analytically and numerically, which presents a non-trivial
cross-check. In Feynman-'t Hooft gauge, the dominant corrections from virtual
KK modes arise from the scalar parts of the -boson penguin diagrams,
including the contributions from the scalar component of the 5D gauge-boson
field and from the charged Goldstone bosons in the Higgs sector. The size of
the KK corrections depends on the parameter , which sets the upper
bound for the anarchic 5D Yukawa matrices. We find that for
the dominant KK corrections are proportional to . We discuss the
phenomenological implications of our results for the branching ratio , the time-dependent CP asymmetry , the
direct CP asymmetry and the CP asymmetry difference
. We can derive a lower bound on the first KK
gluon resonance of TeV for , requiring that at least of
the RS parameter space covers the experimental error margins. We
further discuss the branching ratio and compare
our predictions for and with
phenomenological results derived from model-independent analyses.Comment: 44 pages plus appendix, 10 figures, added equations (58) and (61
Pure xenon hexafluoride prepared for thermal properties studies
Preparation of a xenon hexafluoride and sodium fluoride salt yields a sample of the highest possible purity for use in thermal measurements. The desired hexafluoride can easily be freed from the common contaminants, xenon tetra-fluoride, xenon difluoride, and xenon oxide tetrafluoride, because none of these compounds reacts with sodium fluoride
Labor Law: General Electric’s “Overall Approach” to Bargaining Held a Violation of Good Faith
Inspectera AB är ett företag som erbjuder tjänster i flera olika områden. Ett av dessa områden är utbildning som ges på webben. De erbjuder i nuläget webbutbildningar gjorda i Flash men söker andra alternativ där de kan redigera utbildningar samt integrera webbutbildningarna i deras webbtjänst Inspectera Online. Den här rapporten handlar om skapandet av en prototyp för en webbutbildningsmodul som implementerats på Inspectera Online. Fokus ligger främst på presentationsverktyget i modulen och en jämförelse med liknande verktyg som finns tillgängliga på internet. I resultatet presenteras för- och nackdelar för respektive presentationsverktyg med avseende på funktionalitet och vilka möjligheter till integration som finns
Xenon forms stable compound with fluorine
Experiments show that xenon and fluorine combine readily at 400 deg C to form xenon tetrafluoride, which is colorless, crystalline, chemically stable and solid at room temperature. This process can be used for the separation of xenon from mixtures with other noble gases
Senaatti-kiinteistöjen lämmitysstrategian vaihtoehtokartoitus
Tässä työssä tutkitaan Senaatti-kiinteistöjen lämmitysenergian käyttöä ja lämmitysenergian tuotantotapoja sekä niiden aiheuttamia ympäristövaikutuksia.
Työn teoriaosissa käydään läpi keskeisimmät energiapoliittiset säädökset ja tavoitteet, jotka Suomen valtio on Senaatti-kiinteistöille asettanut. Sen jälkeen esitellään keskeisimmät lämmitysenergian tuotantotavat, primäärienergian käsite sekä yleisimmät primäärienergian-lähteet.
Työn tutkimusosassa tarkastellaan Senaatti-kiinteistöjen tekemiä verkostoluovutuksia ja selvitetään, miten mahdolliset toimenpiteet vaikuttavat primäärienergian kulutukseen ja kuinka ne vähentäisivät Senaatti-kiinteistöjen hiilijalanjälkeä.
Työn taulukoihin ja liitteisiin on koottu Senaatti-kiinteistöjen tämänhetkinen lämmitysenergian hankinta, tehtyjen muutosten tuloksia sekä mahdollisten tulevien muutoksien vaikutuksia
More structural holes, more risk? Network structure and risk perception among marijuana growers
A Rigorous Evaluation of Family Finding in North Carolina
Child Trends evaluated Family Finding services in nine North Carolina counties through a rigorous impact evaluation and an accompanying process study. The impact evaluation involved random assignment of eligible children to a treatment or control group. The treatment group received Family Finding services in addition to traditional child welfare services, whereas the control group received traditional child welfare services only. Eligible children were in foster care; were 10 or older at the time of referral; did not have a goal of reunification; and lacked an identified permanent placement. The accompanying process study examined program outputs, outcomes, and linkages between the project components and other contextual factors
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