Modello dei dati e trattamento del dato sul GIS di scavo

The paper focuses on the problems related to archaeological excavation data management through the use of a GIS solution; it considers aspects ranging from the planning of an open and functional data model, fitting the complexity of stratigraphy, to the possibilities of data processing such as the production of thematic maps or the elaboration of interpretative and predictive models using statistical and mathematical tools. It also discusses the difficulty of 3D data recording, as well as the recent technological development of Internet mapping servers and web-based dynamic GIS systems

Reviewing Traffic ClassificationData Traffic Monitoring and Analysis

Traffic classification has received increasing attention in the last years. It aims at offering the ability to automatically recognize the application that has generated a given stream of packets from the direct and passive observation of the individual packets, or stream of packets, flowing in the network. This ability is instrumental to a number of activities that are of extreme interest to carriers, Internet service providers and network administrators in general. Indeed, traffic classification is the basic block that is required to enable any traffic management operations, from differentiating traffic pricing and treatment (e.g., policing, shaping, etc.), to security operations (e.g., firewalling, filtering, anomaly detection, etc.). Up to few years ago, almost any Internet application was using well-known transport layer protocol ports that easily allowed its identification. More recently, the number of applications using random or non-standard ports has dramatically increased (e.g. Skype, BitTorrent, VPNs, etc.). Moreover, often network applications are configured to use well-known protocol ports assigned to other applications (e.g. TCP port 80 originally reserved for Web traffic) attempting to disguise their presence. For these reasons, and for the importance of correctly classifying traffic flows, novel approaches based respectively on packet inspection, statistical and machine learning techniques, and behavioral methods have been investigated and are becoming standard practice. In this chapter, we discuss the main trend in the field of traffic classification and we describe some of the main proposals of the research community. We complete this chapter by developing two examples of behavioral classifiers: both use supervised machine learning algorithms for classifications, but each is based on different features to describe the traffic. After presenting them, we compare their performance using a large dataset, showing the benefits and drawback of each approac

Synthesis of new tacrine analogues from 4-amino-1H-pyrrole-3-carbonitrile

An easy preparation of 4-aminopyrrole-3-carbonitrile derivatives, and their transformation into new substituted pyrrolo[3,2-b]pyridines is described, in one step, via Friedländer reaction under microwave irradiation and classical heating methods. The use of microwave irradiation led to high conversion and shorter times.Fundação para a Ciência e a Tecnologia (FCT) - NMR Network, REEQ/ 630/QUI/2005, SFRH/BPD/31490/2006Fundo Europeu de Desenvolvimento Regional (FEDER

Electrochemical Reduction of CO2 on Compositionally Variant Au-Pt Bimetallic Thin Films

The electrocatalytic reduction of CO2 on Au-Pt bimetallic catalysts with different compositions was evaluated, offering a platform for uncovering the correlation between the catalytic activity and the surface composition of bimetallic electrocatalysts. The Au-Pt alloy films were synthesized by a magnetron sputtering co-deposition technique with tunable composition. It was found that the syngas ratio (CO:H2) on the Au-Pt films is able to be tuned by systematically controlling the binary composition. This tunable catalytic selectivity is attributed to the variation of binding strength of COOH and CO intermediates, influenced by the surface electronic structure (d-band center energy) which is linked to the surface composition of the bimetallic films. Notably, a gradual shift of the d-band center away from the Fermi level was observed with increasing Au content, which correspondingly reduces the binding strength of the COOH and CO intermediates, leading to the distinct catalytic activity for the reduction of CO2 on the compositionally variant Au-Pt bimetallic films. In addition, the formation of formic acid in the bimetallic systems at reduced overpotentials and higher yield indicates that synergistic effects can facilitate reaction pathways for products that are not accessible with the individual components.</p

Estudo de caso

História Clínica: Um paciente com história de diversas lesões nos membros inferiores foi intervencionado em ambos os pés, onde realizou uma tenossinovectomia dos peroneais com reparação de ruptura desses tendões (ao pé direito em 2006 sendo actualmente ao esquerdo). Avaliação Objectiva: Apresentava dor, edema, limitação articular de todos os movimentos da tibio-társica, fraqueza muscular, pés cavos e alterações do padrão de marcha e do equilíbrio. Objectivo: foi verificar se a mobilização com movimento (MWM) do astrágalo e da articulação tibio-peroneal inferior levava a uma diminuição da dor e aumentava a amplitude de dorsiflexão e inversão neste doente com pé cavo. Intervenção: foi realizada MWM do astrágalo e do perónio na articulação tibioperoneal inferior em descarga e em semi-carga, sendo mantida essa nova posição com uma ligadura de tape. Resultados: o paciente aumentou as amplitudes articulares em descarga e em carga, diminuiu o edema da perna e pé, aumentou a funcionalidade, mas em termos de força muscular não foram quantificadas alterações. Conclusão: mesmo o paciente tendo pé cavo e sequelas de uma tenossinovectomia dos peroneais, as manobras de mobilização com movimento do astrágalo e da articulação tíbio-peroneal inferior levaram a uma eliminação da dor e a um aumento da amplitude articular.Clinical History: A patient with a history of several injuries in the lower limbs was chirurgical intervened on both feet, where he made a peroneal tenosynovectomy with a rupture repair of these tendons (right foot in 2006 and in the present on left). Objective assessment: He had pain, swelling, ankle limitation of all movements, muscle weakness, pes cavus and walk and balance problems. Objective: To ascertain whether the ankle dorsiflexion and inversion mobilization with movement (MWM) result in pain decrease and increased range of motion of dorsiflexion and inversion in this patient with pes cavus. Intervention: MWM was performed in the talus and in the distal joint of the fibula in weight-hearing and in no weight-hearing, being held this new position with tape. Results: The patient increased range of motion in a weight-hearing and in a no weight-hearing position, decreased the swelling of the leg and foot, increased functionality, but in terms of muscle strength the changes were not quantified. Conclusion: Even the patients with pes cavus and with damage of a chirurgical intervention, the mobilization with movement technique of the talus and of the distal fibula joint results in a pain remove and in a increased range of motion

Transiting Exoplanet Studies and Community Targets for JWST's Early Release Science Program

The James Webb Space Telescope will revolutionize transiting exoplanet atmospheric science due to its capability for continuous, long-duration observations and its larger collecting area, spectral coverage, and spectral resolution compared to existing space-based facilities. However, it is unclear precisely how well JWST will perform and which of its myriad instruments and observing modes will be best suited for transiting exoplanet studies. In this article, we describe a prefatory JWST Early Release Science (ERS) program that focuses on testing specific observing modes to quickly give the community the data and experience it needs to plan more efficient and successful future transiting exoplanet characterization programs. We propose a multi-pronged approach wherein one aspect of the program focuses on observing transits of a single target with all of the recommended observing modes to identify and understand potential systematics, compare transmission spectra at overlapping and neighboring wavelength regions, confirm throughputs, and determine overall performances. In our search for transiting exoplanets that are well suited to achieving these goals, we identify 12 objects (dubbed "community targets") that meet our defined criteria. Currently, the most favorable target is WASP-62b because of its large predicted signal size, relatively bright host star, and location in JWST's continuous viewing zone. Since most of the community targets do not have well-characterized atmospheres, we recommend initiating preparatory observing programs to determine the presence of obscuring clouds/hazes within their atmospheres. Measurable spectroscopic features are needed to establish the optimal resolution and wavelength regions for exoplanet characterization. Other initiatives from our proposed ERS program include testing the instrument brightness limits and performing phase-curve observations.(Abridged)Comment: This is a white paper that originated from an open discussion at the Enabling Transiting Exoplanet Science with JWST workshop held November 16 - 18, 2015 at STScI (http://www.stsci.edu/jwst/science/exoplanets). Accepted for publication in PAS

A Dog with Pseudo-Addison Disease Associated with Trichuris vulpis Infection

A female Rottweiler dog was presented with a history of intermittent vomiting and diarrhoea, dysorexia, weakness, and weight loss. Haemocytometry and biochemistry values were within normal ranges except for electrolyte analyses, that demonstrated hyponatremia and hyperkalemia with a decreased sodium/potassium ratio. A diagnosis of hypoadrenocorticism was suspected. Basal and post-ACTH stimulation cortisolemia were within the normal values. Electrocardiography was normal, and thoracic radiography showed no significant modifications. On abdominal ultrasonography, adrenal glands appeared normal, while the bowel was distended, and several thin linear hyperechoic objects floating in the lumen were observed. Two adult female whipworms (Trichuris vulpis) were collected following bowel irrigation. Anthelmintic treatment against the parasite was curative

PNPLA3 GG Genotype and Carotid Atherosclerosis in Patients with Non-Alcoholic Fatty Liver Disease

BACKGROUND AND AIM: To evaluate if the presence of carotid atherosclerosis in patients with NAFLD, could be related to gene variants influencing hepatic fat accumulation and the severity of liver damage. METHODS: We recorded anthropometric, metabolic and histological data(Kleiner score) of 162 consecutive, biopsy-proven Sicilian NAFLD patients. Intima-media thickness(IMT), IMT thickening(IMT≥1 mm) and carotid plaques(focal thickening of >1.3 mm at the level of common carotid artery) were evaluated using ultrasonography. IL28B rs12979860 C>T, PNPLA3 rs738409 C>G, GCKR rs780094 C>T, LYPLAL1 rs12137855 C>T, and NCAN rs2228603 C>T single nucleotide polymorphisms were also assessed. The results were validated in a cohort of 267 subjects with clinical or histological diagnosis of NAFLD from Northern Italy, 63 of whom had follow-up examinations. RESULTS: Carotid plaques, IMT thickening and mean maximum IMT were similar in the two cohorts, whereas the prevalence of diabetes, obesity, NASH, and PNPLA3 GG polymorphism(21%vs.13%, p = 0.02) were significantly higher in the Sicilian cohort. In this cohort, the prevalence of carotid plaques and IMT thickening was higher in PNPLA3 GG compared to CC/CG genotype(53%vs.32%, p = 0.02; 62%vs.28%, p<0.001, respectively). These associations were confirmed at multivariate analyses (OR2.94;95%C.I. 1.12–7.71, p = 0.02, and OR4.11;95%C.I. 1.69–9.96, p = 0.002, respectively), although have been observed only in patients <50years. Also in the validation cohort, PNPLA3 GG genotype was independently associated with IMT thickening in younger patients only (OR: 6.00,95%C.I. 1.36–29, p = 0.01), and to IMT progression (p = 0.05) in patients with follow-up examinations. CONCLUSION: PNPLA3 GG genotype is associated with higher severity of carotid atherosclerosis in younger patients with NAFLD. Mechanisms underlying this association, and its clinical relevance need further investigations