1,347 research outputs found
Multiple shifts and fractional integration in the us and uk unemployment rates
This paper analyses the long-run behaviour of the US and UK unemployment rates by testing for possibly fractional orders of integration and multiple shifts using a sample of over 100 annual observations. The results show that the orders of integration are higher than 0 in both series, which implies long memory. If we assume that the underlying disturbances are white noise, the values are higher than 0.5, i.e., nonstationary. However, if the disturbances are autocorrelated, the orders of integration are in the interval (0, 0.5), implying stationarity and mean-reverting behaviour. Moreover, when multiple shifts are taken into account, unemployment is more persistent in the US than in the UK, implying the need for stronger policy action in the former to bring unemployment back to its original level
Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
This study provides the proof of principle that probing the host and the microbe transcriptomes simultaneously is a valuable means to accessing unique information on host pathogen interactions. Our results also underline the extraordinary plasticity of host cell and pathogen responses to infection, and provide a solid framework to further understand the complex mechanisms involved in immunity to M. tuberculosis and in mycobacterial adaptation to different intracellular environments
Can We Really Prevent Suicide?
Every year, suicide is among the top 20 leading causes of death globally for all ages. Unfortunately, suicide is difficult to prevent, in large part because the prevalence of risk factors is high among the general population. In this review, clinical and psychological risk factors are examined and methods for suicide prevention are discussed. Prevention strategies found to be effective in suicide prevention
include means restriction, responsible media coverage, and general public education, as well identification methods such as screening, gatekeeper training, and primary care physician education. Although the treatment for preventing suicide is difficult, follow-up that includes pharmacotherapy, psychotherapy, or both may be useful. However, prevention methods cannot be restricted to the individual. Community, social, and policy interventions will also be essentia
PENGARUH PSIKOEDUKASI MOBILISASI DINI TERHADAP LAMANYA HARI RAWAT PADA PASIEN POST OPERASI APPENDIKSITIS TAHUN 2020 LITERATURE REVIEW
Mobilisasi dini dilakukan pada pasien post operasi appendiksitis setelah sadar dari pengaruh anastesi untuk membantu proses penyembuhan pasca operasi. Tetapi akibat nyeri, takut jahitan sobek, dan ketidaktahuan mengenai pentingnya mobilisasi dini, pasien post operasi appendiksitis takut dan binggung untuk melakukan mobilisasi dini. Hal ini dapat berdampak pada lamanya hari rawat pasien dirumah sakit menjadi lebih dari 4 hari dan beresiko mengalami luka akibat tirah baring lama dan komplikasi lainnya. Psikoedukasi berupa pemberian pengetahuan dan mendemonstrasikan langsung mengenai mobilisasi dini sesuai dengan standar operasional prosedur, sehingga pasien dapat melakukan mobilisasi dini dengan baik dan dapat mempengaruhi lamanya hari rawat pasien di rumah sakit menjadi lebih singkat. Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh mobilisasi dini terhadap lamanya hari rawat pada pasien post operasi appendiksitis. Jenis penelitian yang digunakan adalah study literature menggunakan tipe kajian systematic review. Pencarian artikel menggunakan Science Direct dan Google Scholar untuk menemukan artikel sesuai kriteria kemudian dilakukan review. Artikel dalam penelitian ini termasuk dalam jenis penelitian pra-eksperimen, quasi eksperiment, dan observasi analitik. Pencarian berbatas mulai dari tahun 2010 hingga tahun 2019 yang diakses fulltext dalam format pdf. Hasil penelitian yang di ambil dari kedua jurnal dan kedua skripsi menunjukkan bahwa pemberian mobilisasi berpengaruh pada memendeknya lama hari rawat pasien post operasi appendiksitis selama perawatan di rumah sakit. Kesimpulan dalam penelitian ini yaitu pemberian mobilisasi terbukti dapat memberikan efek terhadap memendeknya lama hari rawat pada pasien post operasi appendiksitis di rumah sakit
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
School closures during the 2009 influenza pandemic: national and local experiences
published_or_final_versio
Superfluid and dissipative dynamics of a Bose-Einstein condensate in a periodic optical potential
We create Bose-Einstein condensates of Rb-87 in a static magnetic trap with a superimposed blue-detuned 1D optical lattice. By displacing the magnetic trap center we are able to control the condensate evolution. We observe a change in the frequency of the center-of-mass oscillation in the harmonic trapping potential, in analogy with an increase in effective mass. For fluid velocities greater than a local speed of sound, we observe the onset of dissipative processes up to full removal of the superfluid component. A parallel simulation study visualizes the dynamics of the Bose-Einstein condensate and accounts for the main features of the observed behavior
Social Cognitive Role of Schizophrenia Candidate Gene GABRB2
10.1371/journal.pone.0062322PLoS ONE84
Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1:A multicentre cohort follow-up study
Objective:
High sensitivity plasma cardiac troponin-I (cTnI) is emerging as a strong predictor of cardiac events in a variety of settings. We have explored its utility in patients with myotonic dystrophy type 1 (DM1).
Methods:
117 patients with DM1 were recruited from routine outpatient clinics across three health boards. A single measurement of cTnI was made using the ARCHITECT STAT Troponin I assay. Demographic, ECG, echocardiographic and other clinical data were obtained from electronic medical records. Follow up was for a mean of 23 months.
Results:
Fifty five females and 62 males (mean age 47.7 years) were included. Complete data were available for ECG in 107, echocardiography in 53. Muscle Impairment Rating Scale score was recorded for all patients. A highly significant excess (p = 0.0007) of DM1 patients presented with cTnI levels greater than the 99th centile of the range usually observed in the general population (9 patients; 7.6%). Three patients with elevated troponin were found to have left ventricular systolic dysfunction (LVSD), compared with four of those with normal range cTnI (33.3% versus 3.7%; p = 0.001). Sixty two patients had a cTnI level < 5ng/L, of whom only one had documented evidence of LVSD. Elevated cTnI was not predictive of severe conduction abnormalities on ECG, or presence of a cardiac device, nor did cTnI level correlate with muscle strength expressed by Muscle Impairment Rating Scale score.
Conclusions:
Plasma cTnI is highly elevated in some ambulatory patients with DM1 and shows promise as a tool to aid cardiac risk stratification, possibly by detecting myocardial involvement. Further studies with larger patient numbers are warranted to assess its utility in this setting
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