522 research outputs found

    CALDEIRÃO DAS NARRATIVAS – FORMAÇÃO DE PROFESSORES: UMA EXPERIÊNCIA (INTER/TRANS)-DISCIPLINAR EM ARTE E CIÊNCIAS HUMANAS

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    O presente artigo tem como objetivo descrever e analisar as ações levadas a efeito peloCentro de Estudo e Pesquisa Ciranda da Arte durante a realização da Olimpíada de Humanidades,numa ação (inter-, trans-)disciplinar integradora de disciplinas de duas grandes áreas doconhecimento: Arte e Ciências Humanas. Professores das disciplinas sociologia, filosofia, história egeografia, além dos arte/educadores ligados às diversas linguagens da Arte, da região APA PousoAlto, situada na localidade da Chapada dos Veadeiros, receberam, no decorrer da Olimpíada deHumanidades, formação de caráter (inter-, trans-)disciplinar, que ainda se desdobrará em outrasquatro fases específicas de um total de cinco. Nessas ações foram mobilizadas metodologiaspedagógicas que instigaram o questionamento e o autoquestionamento por parte dos educadoresem formação acerca de suas histórias de vida em correspondência com suas atividades docentes.Este trabalho dá conta, portanto, da primeira das cinco fases, cuja ação educativaespecífica se apresenta sob a rubrica de “Sensibilização dos professores”. Descreveremos eanalisaremos, assim, as ações realizadas nesse primeiro momento sob um aporte teóricoespecífico que lhe serviu de base e que apresentou conclusivamente a constatação de que acultura, em toda a complexidade que a caracteriza, encontra-se na raiz de toda e qualqueratividade de cunho pedagógico que se leve ou que se venha levar a efeito. Neste contexto, a(inter-, trans-)disciplinaridade se configura como importante ferramenta da e na práxiseducacional como um todo

    The hunt for formamide in interstellar ices: A toolkit of laboratory infrared spectra in astronomically relevant ice mixtures and comparisons to ISO, Spitzer, and JWST observations

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    This work aims at characterizing the mid-IR spectra of formamide in its pure form as well as in mixtures of the most abundant interstellar ices via laboratory simulation of such ices, as well as demonstrating how these laboratory spectra can be used to search for formamide in ice observations. Mid-IR spectra (4000 - 500 cm1^{-1}, 2.5 - 20 μ\mum) of formamide, both in its pure form as well as in binary and tertiary mixtures with H2_2O, CO2_2, CO, NH3_3, CH3_3OH, H2_2O:CO2_2, H2_2O:NH3_3, CO:NH3_3, and CO:CH3_3OH, are collected at temperatures ranging from 15 - 212 K. Apparent band strengths and positions of eight IR bands of pure amorphous and crystalline formamide at various temperatures are provided. Three bands are identified as potential formamide tracers in observational ice spectra: the overlapping C=O stretch and NH2_2 scissor bands at 1700.3 and 1630.4 cm1^{-1} (5.881 and 6.133 μ\mum), the CH bend at 1388.1 cm1^{-1} (7.204 μ\mum), and the CN stretch at 1328.1 cm1^{-1} (7.529 μ\mum). The relative apparent band strengths, positions, and FWHM of these features in mixtures at various temperatures are also determined. Finally, the laboratory spectra are compared to observational spectra of low- and high-mass young stellar objects as well as pre-stellar cores observed with the Infrared Space Observatory, the Spitzer Space Telescope, and the JWST. A comparison between the formamide CH bend in laboratory data and the 7.24 μ\mum band in the observations tentatively indicates that, if formamide ice is contributing significantly to the observed absorption, it is more likely in a polar matrix. Upper limits ranging from 0.35-5.1\% with respect to H2_{2}O are calculated. These upper limits are in agreement with gas-phase formamide abundances and take into account the effect of a H2_{2}O matrix on formamide's band strengths.Comment: Accepted for publication in A&A. 25 pages, 11 figures, 9 table

    Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

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    Introduction: More than 70 common alleles are known to be involved in breast cancer (BC) susceptibility, and several exhibit significant heterogeneity in their associations with different BC subtypes. Although there are differences in the association patterns between BRCA1 and BRCA2 mutation carriers and the general population for several loci, no study has comprehensively evaluated the associations of all known BC susceptibility alleles with risk of BC subtypes in BRCA1 and BRCA2 carriers. Methods: We used data from 15,252 BRCA1 and 8,211 BRCA2 carriers to analyze the associations between approximately 200,000 genetic variants on the iCOGS array and risk of BC subtypes defined by estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and triple-negative- (TN) status; morphologic subtypes; histological grade; and nodal involvement. Results: The estimated BC hazard ratios (HRs) for the 74 known BC alleles in BRCA1 carriers exhibited moderate correlations with the corresponding odds ratios from the general population. However, their associations with ER-positive BC in BRCA1 carriers were more consistent with the ER-positive as

    Assessing associations between the AURKAHMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

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    While interplay between BRCA1 and AURKA-RHAMM-TPX2-TUBG1 regulates mammary epithelial polarization, common genetic variation in HMMR (gene product RHAMM) may be associated with risk of breast cancer in BRCA1 mutation carriers. Following on these observations, we further assessed the link between the AURKA-HMMR-TPX2-TUBG1 functional module and risk of breast cancer in BRCA1 or BRCA2 mutation carriers. Forty-one single nucleotide polymorphisms (SNPs) were genotyped in 15,252 BRCA1 and 8,211 BRCA2 mutation carriers and subsequently analyzed using a retrospective likelihood appr

    Reconstruction of primary vertices at the ATLAS experiment in Run 1 proton–proton collisions at the LHC

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    This paper presents the method and performance of primary vertex reconstruction in proton–proton collision data recorded by the ATLAS experiment during Run 1 of the LHC. The studies presented focus on data taken during 2012 at a centre-of-mass energy of √s=8 TeV. The performance has been measured as a function of the number of interactions per bunch crossing over a wide range, from one to seventy. The measurement of the position and size of the luminous region and its use as a constraint to improve the primary vertex resolution are discussed. A longitudinal vertex position resolution of about 30μm is achieved for events with high multiplicity of reconstructed tracks. The transverse position resolution is better than 20μm and is dominated by the precision on the size of the luminous region. An analytical model is proposed to describe the primary vertex reconstruction efficiency as a function of the number of interactions per bunch crossing and of the longitudinal size of the luminous region. Agreement between the data and the predictions of this model is better than 3% up to seventy interactions per bunch crossing

    Public Research Institutions and Their Connections with Patents of Companies in Technological and Regional Development

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    The interaction between companies and universities is a central theme in discussions on technology transfer. In Brazil, there is an urgent need to raise awareness of the importance of this cooperative relationship for local and regional development. In this sense, it is observed that the innovation process is strategic so that an institution is strengthened and can fulfill its social mission in economic and regional development. Piauí, according to the IBGE census, has a population estimate of 3,273,227 in 2019. Piaui\u27s per capita income is R$ 817.00 and ranks 24th in Brazil in this regard. With these data, the need arises to intervene scientifically in this reality. The objective of this study is to investigate the partnership relationships between companies and public research institutions in Piauí, in the development and transfer of technologies. Research Institutions are the main promoters of technological development in the state, however, for these technologies to reach productive arrangements, strategic alignment in the management of these technologies is necessary. Documentary research was used, with a quantitative approach. In the exploratory search, INPI\u27s databases (National Institute of Industrial Property) and of Espacenet ( European Patent Office ) was used. We sought to select the companies with relevant economic representativeness in the state scenario and investigated the patent information. In the analysis of the data obtained, the Competitiveness Ranking of the CLP States (Public Leadership) was used to compare Piauí with well positioned states. According to the results found, it is observed that the transfer of technology between research institutions and companies is not evident. However, we can see that there are partnership initiatives with small companies in conducting research that can project a change in this scenario. The low number of patents and public/private partnerships in driving innovation in the state of Piauí, may be related to the low index evidenced by the Competitiveness Ranking of States - CLP

    Programas de Integridade e Comunicação: o desafio da conscientização de empresas públicas federais em relação a projetos anticorrupção

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    o artigo discute como a cultura anticorrupção, fomentada pela criação de Programas de Integridade, tem sido estimulada pelos órgãos de controle federais. Conceitos como o de comunicação interna e cultura organizacional são trabalhados, no intuito de expor a importância da comunicação na criação de mecanismos de mudança cultural. Uma pesquisa de caráter qualitativo, descritivo e exploratório, que utilizou como técnica de pesquisa uma entrevista semiestruturada, foi realizada em uma estatal, investigada pela CGU em 2015. Os resultados preliminares são apresentados nesse artigo e mostram as diferenças presentes nas opiniões dos gestores das áreas de Comunicação Interna e Departamento Compliance e o que tem sido feito para a disseminação dessa cultura anticorrupção

    Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

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    A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

    Programas de Integridade e a avaliação de controle interno da CGU:: uma leitura da política pública em relação à Comunicação Organizacional e à Comunicação Pública

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    O artigo discute a importância da área de Comunicação na implantação de Programas de Integridade/Compliance em estatais brasileiras. Relatórios públicos de quatro estatais (Correios, Banco do Nordeste, Eletronorte e Furnas), produzidos pelo Ministério da Transparência e Controladoria Geral da União (CGU), em 2015, foram descritos quanto à comunicação, de forma qualitativa e descritiva. As análises sobre comprometimento da alta direção, treinamentos, comunicação interna, canais de denúncia e monitoramento foram tabelados para maior entendimento. Os resultados de cada uma das estatais são discutidos de forma comparativa
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