1,024 research outputs found

    Evaluation of a ln tan integral arising in quantum field theory

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    We analytically evaluate a dilogarithmic integral that is prototypical of volumes of ideal tetrahedra in hyperbolic geometry. We additionally obtain new representations of the Clausen function Cl_2 and the Catalan constant G=Cl_2(\pi/2), as well as new relations between sine and Clausen function values.Comment: 24 pages, no figure

    Detailed Analysis of the Pulsations During and After Bursts from the Bursting Pulsar (GRO J1744-28)

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    The hard X-ray bursts observed during both major outbursts of the Bursting Pulsar (GRO J1744-28) show pulsations near the neutron star spin frequency with an enhanced amplitude relative to that of the persistent emission. Consistent with previous work, we find that the pulsations within bursts lag behind their expected arrival times based upon the persistent pulsar ephemeris. For an ensemble of 1293 bursts recorded with the Burst and Transient Source Experiment, the average burst pulse time delay is 61.0 +/- 0.8 ms in the 25 - 50 keV energy range and 72 +/- 5 ms in the 50 - 100 keV band. The residual time delay from 10 to 240 s following the start of the burst is 18.1 +/- 0.7 ms (25 - 50 keV). A significant correlation of the average burst time delay with burst peak flux is found. Our results are consistent with the model of the pulse time lags presented by Miller (1996).Comment: 11 pages, accepted for publication in Ap

    Primary accumulation in the Soviet transition

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    The Soviet background to the idea of primary socialist accumulation is presented. The mobilisation of labour power and of products into public sector investment from outside are shown to have been the two original forms of the concept. In Soviet primary accumulation the mobilisation of labour power was apparently more decisive than the mobilisation of products. The primary accumulation process had both intended and unintended results. Intended results included bringing most of the economy into the public sector, and industrialisation of the economy as a whole. Unintended results included substantial economic losses, and the proliferation of coercive institutions damaging to attainment of the ultimate goal - the building of a communist society

    NEW VISIONS OF AFRICA: HOW AFRICAN STUDENTS AT HISTORICALLY BLACK COLLEGES AND UNIVERSITIES SHAPED BLACK EDUCATION, 1920-1960

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    This dissertation studies the relationship between African migrant students, Historically Black Colleges and Universities, and the Phelps-Stokes Fund. In the early twentieth century, the Phelps-Stokes Fund, a philanthropic organization founded on expanding educational accesses to Africans, African Americans, and Native Americans, launched two educational surveys through Africa. Its educational director, Thomas Jesse Jones, hoped that the tour would provide insight into African educational systems and expand his vision for Black education. The two surveys caught the attention of many Africans interested in expanding their education outside of Africa. As a result, future African state builders such as Nnamdi Azikiwe, Kwame Nkrumah, and several others came to know Thomas Jesse Jones and the Phelps-Stokes Fund. Jones used Phelps-Stokes Fund scholarships to help pay for African students’ college tuition in America, steering them toward schools that encouraged training in agriculture and other trades. Yet by funding students to study in the United States, Jones’ program had the unintended consequence of radicalizing Africans’ beliefs about education and decolonization. At Howard and Lincoln Universities, African students gained access to and studied under important African American educators, particularly William Hansberry and Alain Locke. The lessons students learned inside and outside the classroom helped shape their visions for a new Africa, free from colonial rule. African students also gained a new appreciation for the wider political struggle in which they were engaged. They joined and even formed Pan-African organizations both on and off their college campuses to promote unity and solidarity between people of African descent. They applied these lessons upon their return to the continent, working to undermine colonialism through the creation of new educational centers at the University of Ghana and Nigeria University. Born of a western model for perpetuating industrial education, Jones’ project thus ultimately led to the construction of institutions and identities that helped bring down colonial rule in Africa

    Elevated carbon dioxide and ozone alter productivity and ecosystem carbon content in northern temperate forests

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    Three young northern temperate forest communities in the north‐central United States were exposed to factorial combinations of elevated carbon dioxide ( CO 2 ) and tropospheric ozone (O 3 ) for 11 years. Here, we report results from an extensive sampling of plant biomass and soil conducted at the conclusion of the experiment that enabled us to estimate ecosystem carbon (C) content and cumulative net primary productivity ( NPP ). Elevated CO 2 enhanced ecosystem C content by 11%, whereas elevated O 3 decreased ecosystem C content by 9%. There was little variation in treatment effects on C content across communities and no meaningful interactions between CO 2 and O 3 . Treatment effects on ecosystem C content resulted primarily from changes in the near‐surface mineral soil and tree C, particularly differences in woody tissues. Excluding the mineral soil, cumulative NPP was a strong predictor of ecosystem C content ( r 2  = 0.96). Elevated CO 2 enhanced cumulative NPP by 39%, a consequence of a 28% increase in canopy nitrogen (N) content (g N m −2 ) and a 28% increase in N productivity ( NPP /canopy N). In contrast, elevated O 3 lowered NPP by 10% because of a 21% decrease in canopy N, but did not impact N productivity. Consequently, as the marginal impact of canopy N on NPP (∆ NPP /∆N) decreased through time with further canopy development, the O 3 effect on NPP dissipated. Within the mineral soil, there was less C in the top 0.1 m of soil under elevated O 3 and less soil C from 0.1 to 0.2 m in depth under elevated CO 2 . Overall, these results suggest that elevated CO 2 may create a sustained increase in NPP , whereas the long‐term effect of elevated O 3 on NPP will be smaller than expected. However, changes in soil C are not well‐understood and limit our ability to predict changes in ecosystem C content.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108065/1/gcb12564.pd

    Identifying key drivers of the impact of an HIV cure intervention in sub-Saharan Africa

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    BACKGROUND:  The properties required of an intervention that results in eradication or control of HIV in absence of antiretroviral therapy (ART-free viral suppression) to make it cost-effective in low income settings are unknown. METHODS:  We used a model of HIV and ART to investigate the effect of introducing an ART-free viral suppression intervention in 2022 in an example country of Zimbabwe. We assumed that the intervention (cost: 500)wouldbeaccessiblefor90500) would be accessible for 90% of the population, be given to those on effective ART, have sufficient efficacy to allow ART interruption in 95%, with a rate of viral rebound 5% per year in the first three months, and a 50% decline in rate with each successive year. RESULTS:  An ART-free viral suppression intervention with these properties would result in over 0.53 million disability-adjusted-life-years averted over 2022-2042, with a reduction in HIV programme costs of 300 million (8.7% saving). An intervention of this efficacy costing anything up to $1400 is likely to be cost-effective in this setting. CONCLUSION:  Interventions aimed at curing HIV have the potential to improve overall disease burden and to reduce costs. Given the effectiveness and cost of ART, such interventions would have to be inexpensive and highly effective

    D-cycloserine augmentation of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders: a systematic review and meta-analysis of individual participant data

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    Importance: Whether and under which conditions D-cycloserine (DCS) augments the effects of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders is unclear. Objective: To clarify whether DCS is superior to placebo in augmenting the effects of cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders and to evaluate whether antidepressants interact with DCS and the effect of potential moderating variables. Data Sources: PubMed, EMBASE, and PsycINFO were searched from inception to February 10, 2016. Reference lists of previous reviews and meta-analyses and reports of randomized clinical trials were also checked. Study Selection: Studies were eligible for inclusion if they were (1) double-blind randomized clinical trials of DCS as an augmentation strategy for exposure-based cognitive behavior therapy and (2) conducted in humans diagnosed as having specific phobia, social anxiety disorder, panic disorder with or without agoraphobia, obsessive-compulsive disorder, or posttraumatic stress disorder. Data Extraction and Synthesis: Raw data were obtained from the authors and quality controlled. Data were ranked to ensure a consistent metric across studies (score range, 0-100). We used a 3-level multilevel model nesting repeated measures of outcomes within participants, who were nested within studies. Results: Individual participant data were obtained for 21 of 22 eligible trials, representing 1047 of 1073 eligible participants. When controlling for antidepressant use, participants receiving DCS showed greater improvement from pretreatment to posttreatment (mean difference, -3.62; 95% CI, -0.81 to -6.43; P = .01; d = -0.25) but not from pretreatment to midtreatment (mean difference, -1.66; 95% CI, -4.92 to 1.60; P = .32; d = -0.14) or from pretreatment to follow-up (mean difference, -2.98, 95% CI, -5.99 to 0.03; P = .05; d = -0.19). Additional analyses showed that participants assigned to DCS were associated with lower symptom severity than those assigned to placebo at posttreatment and at follow-up. Antidepressants did not moderate the effects of DCS. None of the prespecified patient-level or study-level moderators was associated with outcomes. Conclusions and Relevance: D-cycloserine is associated with a small augmentation effect on exposure-based therapy. This effect is not moderated by the concurrent use of antidepressants. Further research is needed to identify patient and/or therapy characteristics associated with DCS response.2018-05-0

    Advancing the field of health systems research synthesis.

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    Those planning, managing and working in health systems worldwide routinely need to make decisions regarding strategies to improve health care and promote equity. Systematic reviews of different kinds can be of great help to these decision-makers, providing actionable evidence at every step in the decision-making process. Although there is growing recognition of the importance of systematic reviews to inform both policy decisions and produce guidance for health systems, a number of important methodological and evidence uptake challenges remain and better coordination of existing initiatives is needed. The Alliance for Health Policy and Systems Research, housed within the World Health Organization, convened an Advisory Group on Health Systems Research (HSR) Synthesis to bring together different stakeholders interested in HSR synthesis and its use in decision-making processes. We describe the rationale of the Advisory Group and the six areas of its work and reflects on its role in advancing the field of HSR synthesis. We argue in favour of greater cross-institutional collaborations, as well as capacity strengthening in low- and middle-income countries, to advance the science and practice of health systems research synthesis. We advocate for the integration of quasi-experimental study designs in reviews of effectiveness of health systems intervention and reforms. The Advisory Group also recommends adopting priority-setting approaches for HSR synthesis and increasing the use of findings from systematic reviews in health policy and decision-making

    Anthropogenic alluvium: An evidence-based meta-analysis for the UK Holocene

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    An exploratory meta-analysis of 14C-dated Holocene anthropogenic alluvium (AA) in the UK is presented. AA units were categorized by grain size, catchment area and location, depositional environment, and according to diagnostic criteria linked to recorded types of anthropogenic activity. The oldest AA units date to the Early Bronze Age (c. 4400 cal. BP) and there is an apparent 1500 year lag between the adoption of agriculture (c. 6000 cal. BP) in the UK and any impact on floodplain sedimentation. The earliest influence of farming on UK rivers appears to have been hydrological rather than sedimentological. The mediaeval period was characterized by accelerated sedimentation of fine-grained AA, notably in the smallest catchments. There are some apparent regional differences in the timing of AA formation with earlier prehistoric dates in central and southern parts of the UK
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