1,463 research outputs found
Il concetto cristiano di corporazione in Léon Harmel
«The first modern corporate experiment» was defined by what Pierre Louis Léon Harmel (1829-1915) had achieved in his yarn factory in Val des bois in the town of Warmeriville close to Rheims in the French department of Marne. Harmel was a French Catholic entrepreneur very sensitive to the social issues of his time. Harmel, while he was progressively turning away from the paternalism of his father, although he was nicknamed "le Bon Père", moved along the tracks of the social doctrine of the Church and the principles of social Catholicism, inspired in particular by Œuvre des Cercles by Rene La Tour du Pin and Albert de Mun. He decided to turn his factory in a kind of community where the basic principles of Christian justice could merge with the modern aspirations of organized workers. He played a decisive role concerning the opening of the Church to the problems of modern society. Besides he was a close relative of the pope Leon XIII by whom he was very much appreciated, Harmel tried to put in place practical teachings, showing that the teaching of the social Catholicism was alive and real
PALERMO POST-PRODUCTION. UNA COSTA PER LA CULTURA
l'articolo propone una strategia di riconversione dell'area della costa sud di Palermo a partire dal ciclo della cultura e attraverso l'insediamento di alcune infrastrutture culturali, sia di di recupero che di nuova costruzion
il mare e quella memoria che sa di futuro
L'articolo commenta scientificamente i contenuti dell'Ecomuseo del Mare, un nuovo spazio museale della città di Palermo, illustrandone i temi, i materiali, contenuti espositivi e l'allestimento. L'articolo propone, inoltre, riflessioni teoriche sul ruolo della memoria come materiale per il progetto di architettura e per le trasformazioni urbane e si inserisce all'interno del dibatito scientifico sulle trasformazioni delle città costiere e dei waterfront urbani. Infine, lo scritto descrive il progetto di allestimento dello spazio e il suo rapporto con le odierne ricerche intorno alla disciplina dell'architettura degli interni
Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs.
Effective in vivo use of adeno-associated virus (AAV)-based vectors to achieve gene-specific silencing or upregulation in the central nervous system has been limited by the inability to provide more than limited deep parenchymal expression in adult animals using delivery routes with the most clinical relevance (intravenous or intrathecal). Here, we demonstrate that the spinal pia membrane represents the primary barrier limiting effective AAV9 penetration into the spinal parenchyma after intrathecal AAV9 delivery. We develop a novel subpial AAV9 delivery technique and AAV9-dextran formulation. We use these in adult rats and pigs to show (i) potent spinal parenchymal transgene expression in white and gray matter including neurons, glial and endothelial cells after single bolus subpial AAV9 delivery; (ii) delivery to almost all apparent descending motor axons throughout the length of the spinal cord after cervical or thoracic subpial AAV9 injection; (iii) potent retrograde transgene expression in brain motor centers (motor cortex and brain stem); and (iv) the relative safety of this approach by defining normal neurological function for up to 6 months after AAV9 delivery. Thus, subpial delivery of AAV9 enables gene-based therapies with a wide range of potential experimental and clinical utilizations in adult animals and human patients
Automatic video annotation with forests of fuzzy decision trees
Nowadays, the annotation of videos with high-level semantic concepts or
features is a great challenge. In this paper, this problem is tackled by learning,
by means of Fuzzy Decision Trees (FDT), automatic rules based on a limited
set of examples. Rules intended, in an exploitation step, to reduce the need of
human usage in the process of indexation. However, when addressing large,
unbalanced, multiclass example sets, a single classi er - such as the FDT -
is insu cient. Therefore we introduce the use of forests of fuzzy decision
trees (FFDT) and we highlight: (a) its e ectiveness on a high level feature
detection task, compared to other competitive systems and (b) the e ect on
performance from the number of classi ers point of view. Moreover, since the
resulting indexes are, by their nature, to be used in a retrieval application, we
discuss the results under the lights of a ranking (vs. a classi cation) context.Peer Reviewe
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