User Attitudes on E-Books Collection in Mahatma Gandhi University Library: A Case Study

A study on the user’s attitudes, interest and understanding of e-book collections. The sample taken for the study is the E-book collection developed at the Mahatma Gandhi University Library and its users. The survey assessed the impact of the e-books on teaching learning and research. The problems associated with the use of e-books aware also identified. The inference of the study are that the user’s require an orientation on different types of collections, and also extended facilities for access which is possible in this format

Inflation with f(R,ϕ)f(R,\phi) in Jordan frame

We consider an $f(R)$ action that is non-minimally coupled to a massive scalar field. The model closely resembles scalar-tensor theory and by conformal transformation can be transformed to Einstein frame. To avoid the ambiguity of the frame dependence, we obtain an exact analytical solution in Jordan frame and show that the model leads to a period of accelerated expansion with an exit. Further, we compute the scalar and tensor power spectrum for the model and compare them with observations.Comment: 10 pages, 3 figure

Exact inflationary solutions in exponential gravity

We consider a modified gravity model of the form $f(R,\phi)=R e^{h(\phi)R}$, where the strong gravity corrections are taken to all orders and $\phi$ is a self-interacting massless scalar field. We show that the conformal transformation of this model to Einstein frame leads to non-canonical kinetic term and negates the advantage of the Einstein frame. We obtain exact solutions for the background in the Jordan frame without performing conformal transformations and show that the model leads to inflation with exit. We obtain scalar and tensor power-spectrum in Jordan frame and show that the model leads to red-tilt. We discuss the implications of the same in the light of cosmological observations.Comment: 17 pages, 4 figures, 2 table

Quality Certifications Relevant to Seafood Trade

The fisheries trade is very much linked with various types of certifications to meet different legal, market and customer requirements. This paper contains basic information on relevant certifications in the seafood trade with the broad context of quality, which essentially include environment and safety also

Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA). We studied the effects of 26 drugs and 3 drug combinations on 2 commercially available iPSC-CM types using high-throughput voltage-sensitive dye and microelectrode-array assays being studied for the CiPA initiative and compared the results with clinical QT prolongation and torsade de pointes (TdP) risk. Concentration-dependent analysis comparing iPSC-CMs to clinical trial results demonstrated good correlation between drug-induced rate-corrected action potential duration and field potential duration (APDc and FPDc) prolongation and clinical trial QTc prolongation. Of 20 drugs studied that exhibit clinical QTc prolongation, 17 caused APDc prolongation (16 in Cor.4U and 13 in iCell cardiomyocytes) and 16 caused FPDc prolongation (16 in Cor.4U and 10 in iCell cardiomyocytes). Of 14 drugs that cause TdP, arrhythmias occurred with 10 drugs. Lack of arrhythmic beating in iPSC-CMs for the four remaining drugs could be due to differences in relative levels of expression of individual ion channels. iPSC-CMs responded consistently to human ether-a-go-go potassium channel blocking drugs (APD prolongation and arrhythmias) and calcium channel blocking drugs (APD shortening and prevention of arrhythmias), with a more variable response to late sodium current blocking drugs. Current results confirm the potential of iPSC-CMs for proarrhythmia prediction under CiPA, where iPSC-CM results would serve as a check to ion channel and in silico modeling prediction of proarrhythmic risk. A multi-site validation study is warranted

Evolution of documents - Information and Data objects

The vast amount of data leading to the digital data explosion highlights the fact that the current data definition needs a change as the current systems are unable to track the evolution in a document over time without manual intervention. The concepts of Information and Data objects are introduced in this thesis to track the evolution information in a document. We developed the requirements for such a system in which the evolution information is automatically tracked by tracking the user copy and paste action and then using the data to create the evolution information about a specified document. A case study is discussed to further analyse the information and data flow in a collaboration. We have used this knowledge to design the system and then to implement the system so that the user copy and paste actions can be tracked to create the evolution information. The implementation is then presented to a group of experts to identify the problems and to get the feedback to improve the system