Subjectivity as Self-Acquaintance

Subjectivity is that feature of consciousness whereby there is something it is like for a subject to undergo an experience. One persistent challenge in the study of consciousness is to explain how subjectivity relates to, or arises from, purely physical brain processes. But, in order to address this challenge, it seems we must have a clear explanation of what subjectivity is in the first place. This has proven challenging in its own right. For the nature of subjectivity itself seems to resist straightforward characterization. In this paper, I won't address how subjectivity relates to the physical. Instead, I'll address subjectivity itself. I'll do this by introducing and defending a model of subjectivity based on self-acquaintance. My model does not purport to reduce, eliminate, or naturalize subjectivity, but it does make subjectivity more tractable, less paradoxical, and perhaps less dubious to those averse to obscurity

Dynamic Postural Control in Children:Do the Arms Lend the Legs a Helping Hand?

There is growing empirical evidence lending support to the existence of an “upper body strategy” to extend the ankle and hip strategies in maintaining upright postural stability among adults. Both postural stability and arm movement functions are still developing in children. Therefore, enquiry concerning arm contribution to postural stability among children is needed. This proof of concept study seeks to determine whether the arms play a functionally relevant role in dynamic postural control among children. Twenty-nine children (girls, n = 15; age, 10.6 ± 0.5 years; height, 1.48 ± 0.08 m; mass, 42.8 ± 11.4 kg; BMI, 19.2 ± 3.7 kg/m2) completed three dynamic balance tests; (1) Y Balance test®, (2) timed balance beam walking test, (3) transition from dynamic to static balance using the dynamic postural stability index (DPSI). Each test was performed with free and restricted arm movement. Restricting arm movements elicited a marked degradation in the Y Balance reach distance (all directions, P ≤ 0.001, d = -0.85 to -1.13) and timed balance beam walking test (P ≤ 0.001, d = 1.01), while the DPSI was the only metric that was not different between free and restricted arm movements (P = 0.335, d = -0.08). This study provides direct evidence that the arms play a functionally relevant role in dynamic balance performance among children. These findings may provide the impetus to develop training interventions to improve the use of the arms in activities of daily living

An Application of Multi-band Forced Photometry to One Square Degree of SERVS: Accurate Photometric Redshifts and Implications for Future Science

We apply The Tractor image modeling code to improve upon existing multi-band photometry for the Spitzer Extragalactic Representative Volume Survey (SERVS). SERVS consists of post-cryogenic Spitzer observations at 3.6 and 4.5 micron over five well-studied deep fields spanning 18 square degrees. In concert with data from ground-based near-infrared (NIR) and optical surveys, SERVS aims to provide a census of the properties of massive galaxies out to z ~ 5. To accomplish this, we are using The Tractor to perform "forced photometry." This technique employs prior measurements of source positions and surface brightness profiles from a high-resolution fiducial band from the VISTA Deep Extragalactic Observations (VIDEO) survey to model and fit the fluxes at lower-resolution bands. We discuss our implementation of The Tractor over a square degree test region within the XMM-LSS field with deep imaging in 12 NIR/optical bands. Our new multi-band source catalogs offer a number of advantages over traditional position-matched catalogs, including 1) consistent source cross-identification between bands, 2) de-blending of sources that are clearly resolved in the fiducial band but blended in the lower-resolution SERVS data, 3) a higher source detection fraction in each band, 4) a larger number of candidate galaxies in the redshift range 5 < z < 6, and 5) a statistically significant improvement in the photometric redshift accuracy as evidenced by the significant decrease in the fraction of outliers compared to spectroscopic redshifts. Thus, forced photometry using The Tractor offers a means of improving the accuracy of multi-band extragalactic surveys designed for galaxy evolution studies. We will extend our application of this technique to the full SERVS footprint in the future.Comment: accepted to ApJ, 22 pages, 12 figure

Hardness Assurance for Total Dose and Dose Rate Testing of a State-of-the-Art Off-Shore 32 nm SOI CMOS Processor

No abstract availabl

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae

OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England. METHODS: Clinical isolates collected between 1998 and 2011 were tested for resistance to trimethoprim and sulphonamide. The genetic basis of trimethoprim resistance was determined by shotgun WGS analysis and the subsequent isolation and sequencing of plasmids. RESULTS: A total of 16 (out of 106) A. pleuropneumoniae isolates were resistant to both trimethoprim (MIC >32 mg/L) and sulfisoxazole (MIC ≥256 mg/L), and a further 32 were resistant only to sulfisoxazole (MIC ≥256 mg/L). Genome sequence data for the trimethoprim-resistant isolates revealed the presence of the dfrA14 dihydrofolate reductase gene. The distribution of plasmid sequences in multiple contigs suggested the presence of two distinct dfrA14-containing plasmids in different isolates, which was confirmed by plasmid isolation and sequencing. Both plasmids encoded mobilization genes, the sulphonamide resistance gene sul2, as well as dfrA14 inserted into strA, a streptomycin-resistance-associated gene, although the gene order differed between the two plasmids. One of the plasmids further encoded the strB streptomycin-resistance-associated gene. CONCLUSIONS: This is the first description of mobilizable plasmids conferring trimethoprim resistance in A. pleuropneumoniae and, to our knowledge, the first report of dfrA14 in any member of the Pasteurellaceae. The identification of dfrA14 conferring trimethoprim resistance in A. pleuropneumoniae isolates will facilitate PCR screens for resistance to this important antimicrobial

Preliminary Radiation Testing of a State-of-the-Art Commercial 14nm CMOS Processor/System-on-a-Chip

Hardness assurance test results of Intel state-of-the-art 14nm Broadwell U-series processor / System-on-a-Chip (SoC) for total ionizing dose (TID) are presented, along with exploratory results from trials at a medical proton facility. Test method builds upon previous efforts [1] by utilizing commercial laptop motherboards and software stress applications as opposed to more traditional automated test equipment (ATE)