Community grants: a quick guide to key Internet links

This guide provides links to selected sources of financial assistance to community groups. It does not include links to scholarships, fellowships or research grants

Orbital pseudotumour masquerading as Wegener’s granulomatosis

A twenty-two year old female patient presented with new onset bilateral hard orbital masses and progressively worse tear lake problems. Computed tomography of the orbits revealed poorly differentiated bilateral orbital masses. Laboratory investigation revealed ANCA positivity. Routine biochemical investigations were all within normal limits. CXR was also normal. Biopsy of the orbital masses revealed non-specific histological findings. An initial diagnosis of Granulomatosis with Polyangitis (GPA) was postulated. Oral steroids were given followed by a rapid response to steroid therapy. The working diagnosis of GPA was abandoned and a diagnosis of idiopathic orbital inflammation (IOI), or orbital pseudotumour was made owing to the benign, non-infective, inflammatory pathology with no evident systemic or local cause. Tailoring off of steroids resulted in repeated flare ups, resulting in the initiation of methotrexate therapy. The patient is in remission and is currently on combined steroid and methotrexate treatment. IOI is a diagnosis of exclusion and a rapid response to steroids serves as a diagnostic aid but is not in itself diagnostic.peer-reviewe

A precise determination of alpha_s from LEP thrust data using effective field theory

Starting from a factorization theorem in Soft-Collinear Effective Theory, the thrust distribution in e+e- collisions is calculated including resummation of the next-to-next-to-next-to leading logarithms. This is a significant improvement over previous calculations which were only valid to next-to-leading logarithmic order. The fixed-order expansion of the resummed result approaches the exact fixed-order distribution towards the kinematic endpoint. This close agreement provides a verification of both the effective field theory expression and recently completed next-to-next-to-leading fixed order event shapes. The resummed distribution is then matched to fixed order, resulting in a distribution valid over a large range of thrust. A fit to ALEPH and OPAL data from LEP 1 and LEP 2 produces alpha_s(m_Z)= 0.1172 +/- 0.0010 +/- 0.0008 +/-0.0012 +/- 0.0012, where the uncertainties are respectively statistical, systematic, hadronic, and perturbative. This is one of the world's most precise extractions of alpha_s to date.Comment: 37 pages, 12 figures; v2: hadronization discussion and appendices expande

Household structure and infectious disease transmission

One of the central tenets of modern infectious disease epidemiology is that an understanding of heterogeneities, both in host demography and transmission, allows control to be efficiently optimized. Due to the strong interactions present, households are one of the most important heterogeneities to consider, both in terms of predicting epidemic severity and as a target for intervention. We consider these effects in the context of pandemic influenza in Great Britain, and find that there is significant local (ward-level) variation in the basic reproductive ratio, with some regions predicted to suffer 50% faster growth rate of infection than the mean. Childhood vaccination was shown to be highly effective at controlling an epidemic, generally outperforming random vaccination and substantially reducing the variation between regions; only nine out of over 10 000 wards did not obey this rule and these can be identified as demographically atypical regions. Since these benefits of childhood vaccination are a product of correlations between household size and number of dependent children in the household, our results are qualitatively robust for a variety of disease scenarios

NORSEWInD Data Report and Correction Data for Berlengas : NORSEWInD Report UoSNW026

The flow field over Berlengas has been simulated on both a sub scale wind tunnel model in a low speed wind tunnel and in a computational fluid dynamics simulation. The CFD model has been validated by the results of the wind tunnel simulation. A simulation of measurements that would be made by a ZephIR LiDAR mounted on the island has been undertaken using the CFD results A method by which the distortion to the flow field over an offshore platform, measured by either a met mast or LiDAR, can be corrected back to the free stream value has been presented and verified. Correction factors have been calculated and are included in the appendix to this report. Based on the CFD and wind tunnel data it is was evident that significant flow distortion exists up to 425m above the island

Viewing the current account deficit as a capital inflow

With the 1998 current account deficit approaching $225 billion, attention is again focusing on the deficit's impact on U.S. jobs. Although a high deficit does adversely affect employment in export- and import-competing industries, it also means that considerable foreign capital is flowing into the United States, supporting domestic investment spending that stimulates growth and creates jobs.Balance of trade ; Capital movements ; Capital investments ; Investments ; Employment (Economic theory)

Expertise and public policy: a conceptual guide

This paper seeks to provide a guide to better understand: what is expertise, how to determine who are the relevant experts where it comes to the technical aspects of public policy debates, and how to go about choosing between competing expert claims. Executive summary: In developing policy and assessing program effectiveness, policy makers are required to make decisions on complex issues in areas that involve significant public risks. In this context, policy makers are becoming more reliant on the advice of experts and the institution of expertise. Expert knowledge and advice in fields as diverse as science, engineering, the law and economics is required to assist policy makers in their deliberations on complex matters of public policy and to provide them with an authoritative basis for legitimate decision making. However, at the same time that reliance on expertise and the demands made of it are increasing, expert claims have never been subject to greater levels of questioning and criticism. This problem is compounded by the growing public demand that non-experts should be able to participate in debates over issues that impact on their lives. However their capacity to understand and contribute to the technical aspects of these debates may be either limited or non-existent. This paper provides a guide to assessing who is and who is not an expert in the technical aspects of public policy debates, by providing a framework of levels of expertise. It also notes the importance of identifying the specific fields of expertise relevant to the issue in question. The main focus is on scientific and technical areas, but the issues raised also apply in other domains. It then examines the problem of how non-experts can evaluate expert claims in complex, technical domains. The paper argues that, in the absence of the necessary technical expertise, the only way that non-experts are able to appraise expertise and expert claims is through the use of social expertise. This is expertise using everyday social judgements that enables them to determine who to believe when they are not in a position to judge what to believe. In this context, the paper suggests policy makers ask a series of questions: –      can I make sense of the arguments? –      which experts seems the more credible? –      who has the numbers on their side? –      are there any relevant interests or biases? And –      what are the experts’ track records? By identifying the strengths and limitations of each of these strategies, the paper provides guidance on how each might best be used. It also argues that using them in combination improves their strength and reliability. The role of those who can act as intermediaries between technical experts and non-experts is also examined. The paper makes clear that none of these strategies are without problems, but it postulates that a more systematic approach to how non-experts use social expertise might enhance their ability to become active rather than passive consumers of technical expertise