Evaluation of the Rennes Universal Measurement Method (RUMM), an artificial intelligence application for hand joint angle assessment

International audienceAlthough goniometric measurement is considered the gold standard for the measurement of digital range of motion, visual estimation is often employed due to its simplicity despite being inconsistent with recommended guidelines. We evaluated the Rennes Universal Measurement Method, an innovative tool employing artificial intelligence to concurrently analyse hand joint angles based on a single photograph. We found a strong correlation between the goniometric method and the photograph-based approach (Spearman correlation coefficient 0.7). The mean standard error of measurement was -1 degrees (SD 17 degrees). Regarding reproducibility with different photographic angles, an excellent intraclass correlation coefficient of 0.9 was noted. The tool had a processing time of less than 0.1 s per hand, while traditional goniometric methods took 20-30 s per finger. Combining simplicity, high reproducibility and good inter-rater reliability, this is a potentially useful tool that can be used to monitor patient progress in place of traditional goniometry

Home practice in Mindfulness for Psychosis groups: A systematic review and qualitative study

Objectives: Regular home practice is considered a core component of mindfulness groups and may be associated with better treatment outcomes. This study aimed to 1) review the existing evidence on how much home practice people do in Mindfulness for Psychosis groups, and 2) explore participants’ experiences of the barriers and facilitators to completing home practice in a Mindfulness for Psychosis group using a qualitative study.Methods: In study 1, we conducted a systematic review of Mindfulness for Psychosis studies and extracted data on home practice rates. In study 2, we conducted semi-structured interviews with people who had completed a Mindfulness for Psychosis group (N=5) as part of their routine community care, specifically focusing on experiences of home practice.Results: Out of twenty-two studies included in the systematic review, only 4 reported any data on amount of home practice, and none examined the relationship between completion of home practice and treatment outcomes. In the qualitative study, participants described home practice as being difficult but important. Arising themes were similar to findings from previous (non-psychosis) studies suggesting that generic challenges are common, rather than being specific to psychosis.Conclusions: We recommend that future Mindfulness for Psychosis studies record data on home practice rates, in order to investigate any association between home practice and treatment outcome. Our qualitative findings suggest home practice can be a valued part of a Mindfulness for Psychosis group, and a normalising approach could be taken when and if participants encounter common challenges.</p

Denosumab in the management of Aneurysmal bone cyst

International audienceBACKGROUND: Aneurysmal bone cyst (ABC) is a benign, locally aggressive tumour that arises predominantly in long bones and spine. Following the encouraging results of denosumab use in Giant Cell Tumors (GCT) and the histological similarities between ABC and GCT, the interest on the role of denosumab in the therapeutic arsenal of the most advanced ABC is growing. The purpose of this literature review is to investigate the current state of knowledge about the use of denosumab in ABCs. METHODS: A literature research was conducted through PUBMED, COCHRANE and GOOGLE SCHOLAR using the keywords &quot;aneurysmal bone cyst&quot; AND &quot;denosumab&quot;. Seventeen articles were included. RESULTS: A total of 43 cases were reported in the literature. There were 23 males, 20 females. The mean age was 15,9±8,1 year. Pain relief and neurological improvement were rapid and sustained. Radiological assessment showed ossification and/or volume reduction in 36/39 patients. Eight patients (18,6%) presented a recurrence after or during denosumab therapy of whom 7 were adults. Adverse events occurred in 11 patients, 5 of them were admitted to the intensive care unit due to hypercalcemia. CONCLUSION: Denosumab use in non-surgical ABCs has shown a positive impact in pain and neurological symptoms. The oncological outcome remains unclear with a recurrence rate of 18,6% during/after denosumab therapy, mostly in adults. However, regarding the potential clinical benefits, its use might be discussed in the most advanced cases. Further research and clinical trials are mandatory to precise its belonging in the therapeutic arsenal