On the Intracluster Medium in Cooling Flow & Non-Cooling Flow Clusters

Recent X-ray observations have highlighted clusters that lack entropy cores. At first glance, these results appear to invalidate the preheated ICM models. We show that a self-consistent preheating model, which factors in the effects of radiative cooling, is in excellent agreement with the observations. Moreover, the model naturally explains the intrinsic scatter in the L-T relation, with ``cooling flow'' and ``non-cooling flow'' systems corresponding to mildly and strongly preheated systems, respectively. We discuss why preheating ought to be favoured over merging as a mechanism for the origin of ``non-cooling flow'' clusters.Comment: 4 pages, to appear in the proceedings of the "Multiwavelength Cosmology" Conference held in Mykonos, Greece, June 2003, ed. M. Plionis (Kluwer

A study of the ozonolysis of isoprene in a cryogenic buffer gas cell by high resolution microwave spectroscopy

We have developed a method to quantify reaction product ratios using high resolution microwave spectroscopy in a cryogenic buffer gas cell. We demonstrate the power of this method with the study of the ozonolysis of isoprene, CH2=C(CH3)-CH=CH2, the most abundant, non-methane hydrocarbon emitted into the atmosphere by vegetation. Isoprene is an asymmetric diene, and reacts with O3 at the 1,2 position to produce methyl vinyl ketone (MVK), formaldehyde, and a pair of carbonyl oxides: [CH3CO-CH=CH2 + CH2=OO] + [CH2=O + CH3COO-CH=CH2]. Alternatively, O3 could attack at the 3,4 position to produce methacrolein (MACR), formaldehyde, and two carbonyl oxides [CH2=C(CH3)-CHO + CH2=OO] + [CH2=O + CH2=C(CH3)-CHOO]. Purified O3 and isoprene were mixed for approximately 10 seconds under dilute (1.5-4% in argon) continuous flow conditions in an alumina tube held at 298 K and 5 Torr. Products exiting the tube were rapidly slowed and cooled within the buffer gas cell by collisions with cryogenic (4-7 K) He. High resolution chirped pulse microwave detection between 12 and 26 GHz was used to achieve highly sensitive (ppb scale), isomer-specific product quantification. We observed a ratio of MACR to MVK of 2.1 +/- 0.4 under 1:1 ozone to isoprene conditions and 2.1 +/- 0.2 under 2:1 ozone to isoprene conditions, a finding which is consistent with previous experimental results. Additionally, we discuss relative quantities of formic acid (HCOOH), an isomer of CH2=OO, and formaldehyde (CH2=O) under varying experimental conditions, and characterize the spectroscopic parameters of the singly-substituted 13C trans-isoprene and 13C anti-periplanar-methacrolein species. This work has the potential to be extended towards a complete branching ratio analysis, as well towards the ability to isolate, identify, and quantify new reactive intermediates in the ozonolysis of alkenes

#MeToo in EM: A Multicenter Survey of Academic Emergency Medicine Faculty on Their Experiences with Gender Discrimination and Sexual Harassment

Introduction: Gender-based discrimination and sexual harassment of female physicians are well documented. The #MeToo movement has brought renewed attention to these problems. This study examined academic emergency physicians’ experiences with workplace gender discrimination and sexual harassment.Methods: We conducted a cross-sectional survey of a convenience sample of emergency medicine (EM) faculty across six programs. Survey items included the following: the Overt Gender Discrimination at Work (OGDW) Scale; the frequency and source of experienced and observed discrimination; and whether subjects had encountered unwanted sexual behaviors by a work superior or colleague in their careers. For the latter question, we asked subjects to characterize the behaviors and whether those experiences had a negative effect on their self-confidence and career advancement. We made group comparisons using t-tests or chi-square analyses, and evaluated relationships between gender and physicians’ experiences using correlation analyses.Results: A total of 141 out of 352 (40.1%) subjects completed at least a portion of the survey. Women reported higher mean OGDW scores than men (15.4 vs 10.2; 95% confidence interval [CI], 3.6–6.8). Female faculty were also more likely to report having experienced gender-based discriminatory treatment than male faculty (62.7% vs 12.5%; 95% CI, 35.1%-65.4%), although male and female faculty were equally likely to report having observed gender-based discriminatory treatment of another physician (64.7% vs 56.3%; 95% CI, 8.6%-25.5%). The three most frequent sources of experienced or observed gender-based discriminatory treatment were patients, consulting or admitting physicians, and nursing staff. The majority of women reported having encountered unwanted sexual behaviors in their careers, with a significantly greater proportion of women reporting them compared to men (52.9% vs 26.2%, 95% CI, 9.9%-43.4%). The majority of unwanted behaviors were sexist remarks and sexual advances. Of those respondents who encountered these unwanted behaviors, 22.9% and 12.5% reported at least somewhat negative effects on their self-confidence and career advancement.Conclusion: Female EM faculty perceived more gender-based discrimination in their workplaces than their male counterparts. The majority of female and approximately a quarter of male EM faculty encountered unwanted sexual behaviors in their careers.

Study of new systems concepts for a Titan atmospheric probe

Results of a systems concepts study for a Titan Probe were examined. The key tradeoffs performed are described in detail. Mass breakdown of each Probe subsystem or major element were given. The mission analysis performed to determine compliance with the high altitude sampling and descent time requirements are described. The baseline Descent Module design was derived. The element of the Probe System left on the Carrier after separation were described

Crawling the Cosmic Network: Identifying and Quantifying Filamentary Structure

We present the Smoothed Hessian Major Axis Filament Finder (SHMAFF), an algorithm that uses the eigenvectors of the Hessian matrix of the smoothed galaxy distribution to identify individual filamentary structures. Filaments are traced along the Hessian eigenvector corresponding to the largest eigenvalue, and are stopped when the axis orientation changes more rapidly than a preset threshold. In both N-body simulations and the Sloan Digital Sky Survey (SDSS) main galaxy redshift survey data, the resulting filament length distributions are approximately exponential. In the SDSS galaxy distribution, using smoothing lengths of 10 h^{-1} Mpc and 15 h^{-1} Mpc, we find filament lengths per unit volume of 1.9x10^{-3} h^2 Mpc^{-2} and 7.6x10^{-4} h^2 Mpc^{-2}, respectively. The filament width distributions, which are much more sensitive to non-linear growth, are also consistent between the real and mock galaxy distributions using a standard cosmology. In SDSS, we find mean filament widths of 5.5 h^{-1} Mpc and 8.4 h^{-1} Mpc on 10 h^{-1} Mpc and 15 h^{-1} Mpc smoothing scales, with standard deviations of 1.1 h^{-1} Mpc and 1.4 h^{-1} Mpc, respectively. Finally, the spatial distribution of filamentary structure in simulations is very similar between z=3 and z=0 on smoothing scales as large as 15 h^{-1} Mpc, suggesting that the outline of filamentary structure is already in place at high redshift.Comment: 10 pages, 11 figures, accepted to MNRA

Determining finite strain: how far have we progressed?

One of the main aims in the field of structural geology is the identification and quantification of deformation or strain. This pursuit has occupied geologists since the 1800s, but has evolved dramatically since those early studies. The quantification of strain in sedimentary lithologies was initially restricted to lithologies of known initial shape, such as fossils or reduction spots. In 1967, Ramsay presented a series of methods and calculations, which allowed populations of clasts to be used as strain markers. These methods acted as a foundation for modern strain analysis, and have influenced thousands of studies. This review highlights the significance of Ramsay's contribution to modern strain analysis. We outline the advances in the field over the 50 years since publication of Folding and Fracturing of Rocks, review the existing limitations of strain analysis methods and look to future developments

Female orgasmic disorder

This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of female orgasmic disorder

Tradespace Investigation of a Telescope Architecture for Next-generation Space Astronomy and Exploration

Humanity’s endeavor to further its scientific understanding of the celestial heavens has led to the creation and evolution of increasingly powerful and complex space telescopes. Space telescopes provide a view of the solar system, galaxy, and universe unobstructed by Earth’s atmosphere and have profoundly changed the way people view space. In an effort to further advance space telescope capability and achieve the accompanying scientific understanding, the Massachusetts Institute of Technology (MIT), specifically, course 16.89 Space Systems Engineering, explored the tradespace of architectural enumerations encompassed within the design of an ultraviolet-optical-infrared (UVOIR) space telescope located at Sun-Earth Lagrangian Point Two (SE-L2). SE-L2 presents several advantages as an operating location for a UVOIR telescope such as a thermally stable environment and an orbit that allows the telescope to maintain a constant orientation with respect to all of the primary sources of heat and light. The main disadvantages associated with SE-L2 are caused by its relatively large distance from Earth, which marginalizes the effectiveness of real-time telerobotics because of latency and increases the cost of communications, launch, and servicing. Course 16.89 believes that, for this UVOIR application, the strengths of this operating location outweigh its weaknesses and therefore decided to explore the family of opportunities associated with SE-L2. This course used appropriate performance and system metrics to quantify the effectiveness of the aforementioned architectures and create a Pareto front of viable architectures. Evaluating the designs along the Pareto front allowed the course to characterize and group architectures and present these group-types to stakeholders for the selection of an optimal space telescope according to stakeholder requirements and resources. This course also developed sensitivity analysis, which allowed for a greater understanding of how architectural decisions affect the performance of the satellite. Segmentation, modularity, assembly, autonomy, and servicing were key aspects of this multidimensional analysis given the 16.8-meter class size and location of the telescope. Within the respective operating environment and for a spacecraft of similar characteristics, this model will allow stakeholders to predict the long-term operational effectiveness of different space telescope architectures and capture the synergistic effects of combining various architectural decisions into a spacecraft design. The following sections step through the aforesaid analysis and design efforts conducted in 16.89 beginning with Section III, which explicitly performs the stakeholder analysis and articulates the requirements of the mission. Section IV gives an overview of past designs and expands upon the architecture enumerations pertinent to this project, while Section V presents the methods and metrics by which those architectures will be evaluated and the system metrics which will be balanced and optimized in the creation of this space telescope. Section VI will present the model validation of this project and Section VII will discuss the results and analyses of the project. Finally, Section VIII will explore the future work opportunities of this project, while Section IX will present the conclusions and recommendations drawn from this project.MIT Department of Aeronautics and Astronautic

Preliminary study into the components of the fear-avoidance model of LBP: change after an initial chiropractic visit and influence on outcome

<p>Abstract</p> <p>Background</p> <p>In the last decade the sub grouping of low back pain (LBP) patients according to their likely response to treatment has been identified as a research priority. As with other patient groups, researchers have found few if any factors from the case history or physical examination that are helpful in predicting the outcome of chiropractic care. However, in the wider LBP population psychosocial factors have been identified that are significantly prognostic. This study investigated changes in the components of the LBP fear-avoidance beliefs model in patients pre- and post- their initial visit with a chiropractor to determine if there was a relationship with outcomes at 1 month.</p> <p>Methods</p> <p>Seventy one new patients with lower back pain as their primary complaint presenting for chiropractic care to one of five clinics (nine chiropractors) completed questionnaires before their initial visit (pre-visit) and again just before their second appointment (post-visit). One month after the initial consultation, patient global impression of change (PGIC) scores were collected. Pre visit and post visit psychological domain scores were analysed for any association with outcomes at 1 month.</p> <p>Results</p> <p>Group mean scores for Fear Avoidance Beliefs (FAB), catastrophisation and self-efficacy were all improved significantly within a few days of a patient's initial chiropractic consultation. Pre-visit catastrophisation as well as post-visit scores for catastrophisation, back beliefs (inevitability) and self-efficacy were weakly correlated with patient's global impression of change (PGIC) at 1 month. However when the four assessed psychological variables were dichotomised about pre-visit group medians those individuals with 2 or more high variables post-visit had a substantially increased risk (OR 36.4 (95% CI 6.2-213.0) of poor recovery at 1 month. Seven percent of patients with 1 or fewer adverse psychological variables described poor benefit compared to 73% of those with 2 or more.</p> <p>Conclusions</p> <p>The results presented suggest that catastrophisation, FAB and low self-efficacy could be potential barriers to early improvement during chiropractic care. In most patients presenting with higher psychological scores these were reduced within a few days of an initial chiropractic visit. Those patients who exhibited higher adverse psychology post-initial visit appear to have an increased risk of poor outcome at 1 month.</p