3,134 research outputs found
Modified Regge calculus as an explanation of dark energy
Using Regge calculus, we construct a Regge differential equation for the time
evolution of the scale factor in the Einstein-de Sitter cosmology model
(EdS). We propose two modifications to the Regge calculus approach: 1) we allow
the graphical links on spatial hypersurfaces to be large, as in direct particle
interaction when the interacting particles reside in different galaxies, and 2)
we assume luminosity distance is related to graphical proper distance
by the equation , where the inner product can differ from its usual
trivial form. The modified Regge calculus model (MORC), EdS and CDM
are compared using the data from the Union2 Compilation, i.e., distance moduli
and redshifts for type Ia supernovae. We find that a best fit line through
versus gives a correlation of
0.9955 and a sum of squares error (SSE) of 1.95. By comparison, the best fit
CDM gives SSE = 1.79 using = 69.2 km/s/Mpc, = 0.29
and = 0.71. The best fit EdS gives SSE = 2.68 using =
60.9 km/s/Mpc. The best fit MORC gives SSE = 1.77 and = 73.9 km/s/Mpc
using = 8.38 Gcy and kg, where is the
current graphical proper distance between nodes, is the scaling factor
from our non-trival inner product, and is the nodal mass. Thus, MORC
improves EdS as well as CDM in accounting for distance moduli and
redshifts for type Ia supernovae without having to invoke accelerated
expansion, i.e., there is no dark energy and the universe is always
decelerating.Comment: 15 pages text, 6 figures. Revised as accepted for publication in
Class. Quant. Gra
A design method for entrance sections of transonic wind tunnels with rectangular cross sections
A mathematical technique developed to design entrance sections for transonic or high-speed subsonic wind tunnels with rectangular cross sections is discribed. The transition from a circular cross-section setting chamber to a rectangular test section is accomplished smoothly so as not to introduce secondary flows (vortices or boundary-layer separation) into a uniform test stream. The results of static-pressure measurements in the transition region and of static and total-pressure surveys in the test section of a pilot model for a new facility at the Ames Research Center are presented
Static and dynamic pressure measurements on a NACA 0012 airfoil in the Ames High Reynolds Number Facility
The supercritical flows at high subsonic speeds over a NACA 0012 airfoil were studied to acquire aerodynamic data suitable for evaluating numerical-flow codes. The measurements consisted primarily of static and dynamic pressures on the airfoil and test-channel walls. Shadowgraphs were also taken of the flow field near the airfoil. The tests were performed at free-stream Mach numbers from approximately 0.7 to 0.8, at angles of attack sufficient to include the onset of buffet, and at Reynolds numbers from 1 million to 14 million. A test action was designed specifically to obtain two-dimensional airfoil data with a minimum of wall interference effects. Boundary-layer suction panels were used to minimize sidewall interference effects. Flexible upper and lower walls allow test-channel area-ruling to nullify Mach number changes induced by the mass removal, to correct for longitudinal boundary-layer growth, and to provide contouring compatible with the streamlines of the model in free air
Simulation of turbulent transonic separated flow over an airfoil
A code developed for simulating high Reynolds number transonic flow fields of arbitrary configuration is described. This code, in conjunction with laboratory experiments, is used to devise and test turbulence transport models which may be suitable in the prediction of such flow fields, with particular emphasis on regions of flow separation. The solutions describe the flow field, including both the shock-induced and trailing-edge separation regions, in sufficient detail to provide the profile and friction drag
Self-similar structure and experimental signatures of suprathermal ion distribution in inertial confinement fusion implosions
The distribution function of suprathermal ions is found to be self-similar
under conditions relevant to inertial confinement fusion hot-spots. By
utilizing this feature, interference between the hydro-instabilities and
kinetic effects is for the first time assessed quantitatively to find that the
instabilities substantially aggravate the fusion reactivity reduction. The ion
tail depletion is also shown to lower the experimentally inferred ion
temperature, a novel kinetic effect that may explain the discrepancy between
the exploding pusher experiments and rad-hydro simulations and contribute to
the observation that temperature inferred from DD reaction products is lower
than from DT at National Ignition Facility.Comment: Revised version accepted for publication in PRL. "Copyright (2015) by
the American Physical Society.
An experimental and computational investigation of the flow field about a transonic airfoil in supercritical flow with turbulent boundary-layer separation
A combined experimental and computational research program is described for testing and guiding turbulence modeling within regions of separation induced by shock waves incident in turbulent boundary layers. Specifically, studies are made of the separated flow the rear portion of an 18%-thick circular-arc airfoil at zero angle of attack in high Reynolds number supercritical flow. The measurements include distributions of surface static pressure and local skin friction. The instruments employed include highfrequency response pressure cells and a large array of surface hot-wire skin-friction gages. Computations at the experimental flow conditions are made using time-dependent solutions of ensemble-averaged Navier-Stokes equations, plus additional equations for the turbulence modeling
Between the Balkans and the Baltic : phylogeography of a common vole mitochondrial DNA lineage limited to Central Europe
The common vole (Microtus arvalis) has been a model species of small mammal for studying
end-glacial colonization history. In the present study we expanded the sampling from
central and eastern Europe, analyzing contemporary genetic structure to identify the role of
a potential `northern glacial refugium', i.e. a refugium at a higher latitude than the traditional
Mediterranean refugia. Altogether we analyzed 786 cytochrome b (cytb) sequences (representing
mitochondrial DNA; mtDNA) from the whole of Europe, adding 177 new sequences
from central and eastern Europe, and we conducted analyses on eight microsatellite loci for
499 individuals (representing nuclear DNA) from central and eastern Europe, adding data
on 311 new specimens. Our new data fill gaps in the vicinity of the Carpathian Mountains,
the potential northern refugium, such that there is now dense sampling from the Balkans to
the Baltic Sea. Here we present evidence that the Eastern mtDNA lineage of the common
vole was present in the vicinity of this Carpathian refugium during the Last Glacial Maximum
and the Younger Dryas. The Eastern lineage expanded from this refugium to the Baltic and
shows low cytb nucleotide diversity in those most northerly parts of the distribution. Analyses
of microsatellites revealed a similar pattern but also showed little differentiation between
all of the populations sampled in central and eastern Europe
Zinc stress induces copper depletion in Acinetobacter baumannii
Background: The first row transition metal ions zinc and copper are essential to the survival of many organisms, although in excess these ions are associated with significant toxicity. Here, we examined the impact of zinc and copper stress on Acinetobacter baumannii, a common opportunistic pathogen. Results: We show that extracellular zinc stress induces a copper-specific depletion phenotype in A. baumannii ATCC 17978. Supplementation with copper not only fails to rescue this phenotype, but further exacerbates the copper depletion. Extensive analysis of the A. baumannii ATCC 17978 genome identified 13 putative zinc/copper resistance efflux pumps. Transcriptional analyses show that four of these transporters are responsive to zinc stress, five to copper stress and seven to the combination of zinc and copper stress, thereby revealing a likely foundation for the zinc-induced copper starvation in A. baumannii. In addition, we show that zinc and copper play crucial roles in management of oxidative stress and the membrane composition of A. baumannii. Further, we reveal that zinc and copper play distinct roles in macrophage-mediated killing of this pathogen. Conclusions: Collectively, this study supports the targeting of metal ion homeostatic mechanisms as an effective antimicrobial strategy against multi-drug resistant bacterial pathogens.Karl A. Hassan, Victoria G. Pederick, Liam D. H. Elbourne, Ian T. Paulsen, James C. Paton, Christopher A. McDevitt and Bart A. Eijkelkam
Influenza Virus Aerosols in Human Exhaled Breath: Particle Size, Culturability, and Effect of Surgical Masks
The CDC recommends that healthcare settings provide influenza patients with facemasks as a means of reducing transmission to staff and other patients, and a recent report suggested that surgical masks can capture influenza virus in large droplet spray. However, there is minimal data on influenza virus aerosol shedding, the infectiousness of exhaled aerosols, and none on the impact of facemasks on viral aerosol shedding from patients with seasonal influenza. We collected samples of exhaled particles (one with and one without a facemask) in two size fractions (“coarse”>5 µm, “fine”≤5 µm) from 37 volunteers within 5 days of seasonal influenza onset, measured viral copy number using quantitative RT-PCR, and tested the fine-particle fraction for culturable virus. Fine particles contained 8.8 (95% CI 4.1 to 19) fold more viral copies than did coarse particles. Surgical masks reduced viral copy numbers in the fine fraction by 2.8 fold (95% CI 1.5 to 5.2) and in the coarse fraction by 25 fold (95% CI 3.5 to 180). Overall, masks produced a 3.4 fold (95% CI 1.8 to 6.3) reduction in viral aerosol shedding. Correlations between nasopharyngeal swab and the aerosol fraction copy numbers were weak (r = 0.17, coarse; r = 0.29, fine fraction). Copy numbers in exhaled breath declined rapidly with day after onset of illness. Two subjects with the highest copy numbers gave culture positive fine particle samples. Surgical masks worn by patients reduce aerosols shedding of virus. The abundance of viral copies in fine particle aerosols and evidence for their infectiousness suggests an important role in seasonal influenza transmission. Monitoring exhaled virus aerosols will be important for validation of experimental transmission studies in humans
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