Old Regrowth Forest Patches as Habitat for the Conservation of Avian Diversity in a Southwest Ohio Landscape

Author Institution: Department of Geography, Miami UniversityLandscape fragmentation and chronic habitat loss are potentially profound obstacles to the protection of mature forest birds in the eastern deciduous forest of the Corn Belt agricultural region. Because of the general absence of large remnant forests, conservation efforts need to better understand the role of very small ‘regrowth’ patches for bird conservation. This study investigated how small old regrowth forests contribute to regional bird diversity and differ in composition in relation to their physical, ecological, and landscape attributes. From May to late June 2009, we measured forest composition and structure, and conducted avian point count surveys in nine regrowth patches, 0.9 - 11.2 ha, embedded in the Miami University Natural Areas, Butler County, Ohio. These small patches conserved 68 percent of the recorded regional birds, including 94 percent of mature forest breeders. Site differences among the nine patches explained the designation of avian community types as primarily upland, floodplain, and transitional between these settings. These findings demonstrate the conservation significance of small, old regrowth patches for mature forest birds and support the conservation of these forests across a range of physical, ecological, and landscape settings

The hullaballoo over e-learning? Technology and pluralism in economics

E-learning vs. “talk and chalk”: this binary opposition presents a conflict that has dominated existing pedagogical research. That technological innovation offers an alternative for pressured educationists to improve efficiency and question the cost-effectiveness of traditional teaching methods creates a false dichotomy. This paper addresses the influence of the erroneous “either/or” position and discards it. It claims that there is no fundamental antagonism between the two methods of instruction and proffers the alternative found in blended learning methods. The meticulous splicing of e-learning and traditional lectures liberates the Economics lecturer to deliver a pluralist perspective. Thus, technology becomes a vital tool enabling educators to escape from the limitation of monist teaching methods and guarantees that economics students can fully engage with the discipline’s vibrant debates. “Contest and controversy; orthodoxy and heterodoxy; critique and reject”: technology’s real role is to facilitate a workable space for the free thinking mind

Resuscitation and quantification of stressed Escherichia coli K12 NCTC8797 in water samples

The aim of this study was to investigate the impact on numbers of using different media for the enumeration of Escherichia coli subjected to stress, and to evaluate the use of different resuscitation methods on bacterial numbers. E. coli was subjected to heat stress by exposure to 55 °C for 1 h or to light-induced oxidative stress by exposure to artificial light for up to 8 h in the presence of methylene blue. In both cases, the bacterial counts on selective media were below the limits of detection whereas on non-selective media colonies were still produced. After resuscitation in non-selective media, using a multi-well MPN resuscitation method or resuscitation on membrane filters, the bacterial counts on selective media matched those on non-selective media. Heat and light stress can affect the ability of E. coli to grow on selective media essential for the enumeration as indicator bacteria. A resuscitation method is essential for the recovery of these stressed bacteria in order to avoid underestimation of indicator bacteria numbers in water. There was no difference in resuscitation efficiency using the membrane filter and multi-well MPN methods. This study emphasises the need to use a resuscitation method if the numbers of indicator bacteria in water samples are not to be underestimated. False-negative results in the analysis of drinking water or natural bathing waters could have profound health effects

The Microglial Sensome Revealed by Direct RNA Sequencing

Microglia, the principal neuroimmune sentinels of the brain, continuously sense changes in their environment and respond to invading pathogens, toxins and cellular debris. Microglia exhibit plasticity and can assume neurotoxic or neuroprotective priming states that determine their responses to danger. We used direct RNA sequencing, without amplification or cDNA synthesis, to determine the quantitative transcriptomes of microglia of healthy adult and aged mice. We validated our findings by fluorescent dual in-situ hybridization, unbiased proteomic analysis and quantitative PCR. We report here that microglia have a distinct transcriptomic signature and express a unique cluster of transcripts encoding proteins for sensing endogenous ligands and microbes that we term the “sensome”. With aging, sensome transcripts for endogenous ligand recognition are downregulated, whereas those involved in microbe recognition and host defense are upregulated. In addition, aging is associated with an overall increase in expression of microglial genes involved in neuroprotection

Efficacy of Online Training for Improving Camp Staff Competency

Preparing competent staff is a critical issue within the camp community. This quasi-experimental study examined the effectiveness of an online course for improving staff competency in camp healthcare practices among college-aged camp staff and a comparison group (N = 55). We hypothesized that working in camp would increase competency test scores due to opportunities for staff to experientially apply knowledge learned online. Hierarchical linear modeling was used to analyse the cross-level effects of a between-individuals factor (assignment to experimental or comparison group) and within-individual effects of time (pre-test, post-test #1, and post-test #2) on online course test scores. At post-test #2, the difference in average test scores between groups was ~30 points, with the treatment group scoring lower on average than the comparison group. Factors that may have influenced these findings are explored, including fatigue and the limited durability of online learning. Recommendations for research and practice are discussed

Scara1 deficiency impairs clearance of soluble Amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

In Alzheimer’s disease soluble amyloid beta (sAβ) causes synaptic dysfunction and neuronal loss. Receptors involved in clearance of sAβ are not known. Here we use shRNA screening and identify the scavenger receptor Scara1 as a receptor for sAβ expressed on myeloid cells. To determine the role of Scara1 in clearance of sAβ in vivo, we cross Scara1 null mice with PS1-APP mice, a mouse model of Alzheimer’s disease and generate PS1-APP- Scara1-deficient mice. Scara1 deficiency markedly accelerates Aβ accumulation leading to increased mortality. In contrast, pharmacological upregulation of Scara1 expression on mononuclear phagocytes increases Aβ clearance. This approach is a potential treatment strategy for Alzheimer’s disease

Scara1 deficiency impairs clearance of soluble Amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

In Alzheimer’s disease soluble amyloid beta (sAβ) causes synaptic dysfunction and neuronal loss. Receptors involved in clearance of sAβ are not known. Here we use shRNA screening and identify the scavenger receptor Scara1 as a receptor for sAβ expressed on myeloid cells. To determine the role of Scara1 in clearance of sAβ in vivo, we cross Scara1 null mice with PS1-APP mice, a mouse model of Alzheimer’s disease and generate PS1-APP- Scara1-deficient mice. Scara1 deficiency markedly accelerates Aβ accumulation leading to increased mortality. In contrast, pharmacological upregulation of Scara1 expression on mononuclear phagocytes increases Aβ clearance. This approach is a potential treatment strategy for Alzheimer’s disease

Spurious Legislation and Spurious Mandamus in Florida

The Florida Supreme Court has, in a number of recent cases, issued peremptory writs of mandamus directing the secretary of state to expunge designated wording from the official legislative record, of which he is the constitutional custodian. The author argues that these holdings constitute a clear abuse of this extraordinary writ, most recently as a mere pretext for bringing a constitutional challenge to the validity of a statute within the original jurisdiction of the supreme court. The author also proposes a conceptual framework for dealing with a material variation in wording between a bill as enacted by the legislature and the same bill as it is signed into law by the governor