Redefining climate change inaction as temporal intergroup bias: Temporally adapted interventions for reducing prejudice may help elicit environmental protection

The consequences of the environmental decisions we make today will bear upon future generations of people. We argue that the framing of climate change is inherently intergroup in nature and suggest a reason for inaction on climate change is the perception of future generations as an outgroup. We test whether a technique adapted from the realm of intergroup relations may provide a novel approach to encouraging more sustainable environmental conduct. In Study 1 we found that participants who completed a simple social categorization technique designed to reduce (temporal) intergroup bias subsequently displayed a heightened preference for sustainable goods in a product choice task. Study 2 replicated these results with an alternative measure of pro-environmental intentions, and confirmed that the effect of the intervention on environmental outcomes was explained by changes in intergroup perception

Member-to-member generalisation in trust behaviour: How do prior experiences inform prosocial behaviour towards novel ingroup and outgroup members

Trust in individuals is strongly guided by group membership; ingroup favouritism in trust is a very robust finding in the literature on pro-social behaviour. We know, however, that group attitudes can change based on discrete encounters with group members (i.e., intergroup contact). This research examines how people use previous experiences with ingroup and outgroup members to inform decisions to trust novel, unknown group members. This process, which we refer to as member-to-member generalisation, was examined in two studies using a student sample (N = 135) and a larger and more representative online sample (N = 226). The moderating effects of group membership (ingroup vs outgroup vs unknown) and interaction valence (positive vs negative) on member-to-member generalisation were explored in ten sequential Trust Games. We examined changes in investment behaviour based on feedback from the previous partner, where feedback was either positive (high reciprocation) or negative (no reciprocation). We observed consistent evidence for member-to-member generalisation. People did not just rely on initial group attitudes to guide their trust behaviour, but adjusted their behaviour towards novel individuals based on previous experiences. Generalisation was stronger for interactions that were negative and seemingly unexpected. When people showed strong distrust of the outgroup (Study 1) or were highly identified with the ingroup (Study 2), they changed their behaviour towards novel partners more after experiencing incongruent interactions. These findings are discussed in relation to intergroup contact theory, outgroup homogeneity, and expectancy violation effects

Turn off the Tap: Behavioural messages increase water efficiency during toothbrushing

Reducing consumer demand is part of a multidimensional strategy to increase water resilience. Theory-based ‘nudges’ or behaviour-change strategies may be effective at reducing demand at little cost. This paper reports a unique partnership between GlaxoSmithKline, water utility Anglian Water, and researchers at the University of East Anglia. Two experimental studies drawing on the strengths of these organizations investigated a behaviour change intervention designed to reduce water usage when toothbrushing. Study 1 tested the efficacy of three theory-based behavioural messages (social norms, ingroup norms, and collective efficacy) designed to encourage participants (N = 164) to turn off the tap whilst brushing teeth. In an actual toothbrushing scenario, all three messages proved to be effective compared to a no-treatment control condition. In study 2, homes in Newmarket, Suffolk (N = 382) were given toothbrushing packs containing a collective efficacy message that highlighted turning off the tap while toothbrushing. Smart-meter recorded water usage was obtained for three weeks before and three weeks after receiving the toothbrushing packs. Household water usage significantly decreased after receiving the packs. A control group of N = 382 households did not show a significant decrease in water usage during this timeframe. These studies suggest that behavioural messages from public or private companies can be effective in reducing real-world water usage while toothbrushing. This model of collaboration between industry, water utilities, and academics can serve as a model of best practice for public and private companies interested in reducing household water usage

Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells

Conditioned medium (CM) from clonal sub-populations of the pancreatic cancer cell line, MiaPaCa-2 with differing invasive abilities, were examined for their effect on in vitro invasion. Conditioned medium from Clone #3 (CM#3) strongly promoted invasion, while CM from Clone #8 (CM#8) inhibited invasion in vitro. 2D DIGE followed by MALDI-TOF MS analysis of CM#3 and CM#8 identified 41 proteins which were differentially regulated; 27 proteins were down-regulated and 14 proteins up-regulated in the invasion-promoting CM#3 when compared to CM#8. Western blotting analysis confirmed the down-regulated expression of gelsolin and the up-regulation of aldehyde dehydrogenase 1A1 in CM#3. Down-regulation of aldehyde dehydrogenase 1A1 in Clone #3 CM and gelsolin levels in Clone #8 CM by siRNA transfection revealed an important involvement of these proteins in promoting and inhibiting invasion in these pancreatic cancer cell lines

Everyday cosmopolitanism in representations of Europe among young Romanians in Britain

The paper presents an analysis of everyday cosmopolitanism in constructions of Europe among young Romanian nationals living in Britain. Adopting a social representations approach, cosmopolitanism is understood as a cultural symbolic resource that is part of everyday knowledge. Through a discursively-oriented analysis of focus group data, we explore the ways in which notions of cosmopolitanism intersect with images of Europeanness in the accounts of participants. We show that, for our participants, representations of Europe are anchored in an Orientalist schema of West-vs.-East, whereby the West is seen as epitomising European values of modernity and progress, while the East is seen as backward and traditional. Our findings further show that representations of cosmopolitanism reinforce this East/West dichotomy, within a discourse of ‘Occidental cosmopolitanism’. The paper concludes with a critical discussion of the diverse and complex ideological foundations of these constructions of European cosmopolitanism and their implications

When contact goes wrong: Negative intergroup contact promotes generalized outgroup avoidance

This paper broadens our understanding of the consequences of negative intergroup contact. Study 1 reports cross-sectional evidence that negative contact with European immigrants in Britain is not only associated with increased prejudice, but also the avoidance of future contact with this group. Studies 2A and 2B provided an experimental replication in a different intergroup context. A negative encounter with an outgroup member, but not an ingroup member, was found to reduce intentions to engage in contact with the outgroup in the future. Study 3 went on to demonstrate that the effect of negative contact on outgroup avoidance is not limited to the contacted outgroup, but is indirectly associated with reduced intentions to engage with other, secondary outgroups—an effect we refer to as avoidance generalization effect. Negative contact was also associated with lower general contact self-efficacy. Together, findings suggest that negative contact is damaging not just because it increases prejudice but also because it compromises future engagement with diversity

Redefining climate change inaction as temporal intergroup bias: Temporally adapted interventions for reducing prejudice may help elicit environmental protection

The consequences of the environmental decisions we make today will bear upon future generations of people. We argue that the framing of climate change is inherently intergroup in nature and suggest a reason for inaction on climate change is the perception of future generations as an outgroup. We test whether a technique adapted from the realm of intergroup relations may provide a novel approach to encouraging more sustainable environmental conduct. In Study 1 we found that participants who completed a simple social categorization technique designed to reduce (temporal) intergroup bias subsequently displayed a heightened preference for sustainable goods in a product choice task. Study 2 replicated these results with an alternative measure of pro-environmental intentions, and confirmed that the effect of the intervention on environmental outcomes was explained by changes in intergroup perception

Can past intergroup contact shape support for policies in a pandemic? Processes predicting endorsement of discriminatory Chinese restrictions during the COVID-19 crisis

A survey of 340 UK residents was conducted when the COVID-19 virus first reached the UK in February 2020. We measured past experiences of positive and negative intergroup contact with Chinese people as predictors of intergroup threat and emotions in the context of the pandemic; and how these processes in turn predicted support for discriminatory policies designed to restrict the freedom of Chinese people in the UK. We tested a novel threat-matching hypothesis which draws upon models of outgroup-specific social perception to predict that the emotional processes underlying contact effects will depend on the specific threat posed by the outgroup. In the present epidemiological context, Chinese people posed a salient threat to individuals’ physical health and welfare. Accordingly, we show that whilst intergroup contact predicted both fear and anger towards the outgroup, the indirect effect of contact on support for Chinese restriction policies via fear was significantly stronger than the indirect effect via anger. Our findings provide a more nuanced understanding of how specific threat and emotions drive intergroup contact effects, and offer important insights for efforts to maintain positive intergroup relations in the face of the crisis

Serum-free cell growth and differentiation studies in cultured cell lines

The thesis is divided into two main sections investigating growth and differentiation in cultured cell lines. Investigations were carried out into the establishment of serum-free media (SFM) for the long-term subcultivation of the industrially important cell line, CHO-K1. When the cell line was cultured in a high calcium containing medium, cellular growth was found to be inhibited after 4 to 6 passages on average. However, by growing the cells in a low calcium medium, continuous cultivation was possible. It appears that the calcium concentration in the SFM is critical to this long-term growth. The SFM developed were also capable of supporting growth of CHO-K1 in suspension culture with Pluronic F68 supplementation and in microcarrier culture. Serum-free media was also developed for the growth and sub-cultivation of a human lung cancer cell line, DLKP. This cell line contains three morphologically distinct subpopulations. The growth pattern of the three clones differed in serum-free medium with only one of them, DLKP-I, capable of proliferating in the above medium. However, the addition of fibronectin to the SFM permitted growth of the other two clones. All sub-populations could be subcultured indefinitely in SFM. DLKP-A, a multiple drug resistant variant of the parental DLKP cell line, was also successfully grown and subcultured in SFM. Differentiation studies were also carried out on DLKP. This cell line was originally histologically diagnosed as a ‘poorly differentiated carcinoma of the lung’. Treatment of the cells with the differentiation-inducing agent, 5-bromodeoxyuridine (BrdU) resulted in the induction of integrin and upregulation of a2p, integrin expression. Associated with this change in integrin expression was a functional change in the properties of the cells themselves with BrdU treatment. The cells developed different adhesive properties showing more rapid attachment to the extracellular matrix proteins, collagen, laminin and fibronectin, and to basement membrane compared to untreated cells. Addition of an anti-integrin blocking antibody to BrdU-treated cells reversed the changes in adhesive properties of the cells. BrdU treatment of DLKP cells also induced the expression of a number of epithelial antigens, including epithelial specific antigen (a cellular adhesion molecule) and keratin 19 filaments. A significant upregulation of keratin 19 protein expression was also observed in the human lung adenocarcinoma cell line, A549, after BrdU treatment. Preliminary RT-PCR analysis has shown that the effect of BrdU on keratin 19 mRNA expression appears to be at the post-transcriptional/ translational level