Familial hematuria

Hematuria is a common presenting complaint in pediatric nephrology clinics and often has a familial basis. This teaching article provides an overview of causes, diagnosis, and management of the major forms of familial hematuria, Alport syndrome, and thin basement membrane nephropathy

Re: Detection of newly described astrovirus MLB1 in stool samples from children

non applicabil

Searching for HAdV-52, the putative gastroenteritis-associated human adenovirus serotype in Southern Hungary

Human adenovirus (HAdV) serotype 52 has recently been discovered in the United States in samples from human patients with gastroenteritis of unknown etiology and is suspected to be a new human enteric pathogen. The aim of the present pilot study was to investigate whether this virus is circulating in the population of Southern Hungary by screening stool specimens collected from gastroenteritis cases and communal sewage samples in the area of Baranya County. A total of 209 diarrheic stool (124 from children and 85 from adults) and 45 influent sewage samples were screened for HAdV-52 by PCR using a primer pair specific to the gene of 12.5K protein in the E3 genomic region. The novel human adenovirus was not detected in any of the tested samples, suggesting that HAdV-52 was not circulating in the target population and the area during the study period. Since temporal and geographical fluctuations may markedly affect the epidemiology of human enteric pathogens, additional investigations are required to gain more in- depth insights into the ecology of this novel adenovirus

Palaeoecology and palaeoclimatic context of Romanian Carpathian MIS 3 cave bears using stable isotopes (δ13C and δ18O)

International audienceMillimeter-scale growth rings in canine dentine of MIS 3 cave bears have been interpreted as annual growth bands produced, in part, by seasonal variation in growth rate. We present new intra-tooth stable carbon (δ 13 C) and oxygen (δ 18 O) isotope profiles in dentine hydroxyapatite of early forming permanent teeth from three famous Late Pleistocene cave bear sites from Romanian Carpathians. We measured δ 13 C and δ 18 O of the CO 3 fraction of dentine hydroxyapatite from samples covering consecutive inferred years of growth in canines. The δ 13 C values retrieved from the dentine layers-from the oldest to the newest-of the same individual, record an increase throughout immature life of bears as has been shown previously, with lower precision, using age categories. For the first time, based on δ 13 C data analysis, the weaning process in cave bears was identified. The δ 18 O values show substantial variations related, most probably, to seasonal growth of the dentine. Finally, the CO 3 of dentine apatite extracted from cave bear canines proves to be reliable for geochemical analyses, reflecting palaeoclimate conditions, physiology and behavior