Antioxidant and antimicrobial activities of Morchella conica Pers.

Antioxidant capacity and antimicrobial activities of Morchella conica Pers. extracts obtained with ethanol were investigated in this study. Four complementary test systems; namely DPPH free radical scavenging, -carotene/linoleic acid systems, total phenolic compounds and total flavonoid concentration were used. Inhibition values of M. conica ethanol extracts, buthylated hydroxyanisol (BHA) and -tocopherol standards were found to be 96.9, 98.9 and 99.2%, respectively, at aconcentration of 160 ìg/ml. When compared the inhibition levels of methanol extract of M. conica and standards in linoleic acid system, it was observed that the higher the concentration of both M. conicaethanol extract and the standards the higher the inhibition effect. Total flavonoid amount was 9.17±0.56ìg mg-1 quercetin equivalent while the phenolic compound amount was 41.93±0.29 ìg mg-1 pyrocatecholequivalent in the ethanolic extract. The antimicrobial effect of M. conica ethanol extract was tested against six species of Gram-positive bacteria, seven species of Gram-negative bacteria and one speciesof yeast. The M. conica ethanol extract had a narrow antibacterial spectrum against tested microorganisms. The most susceptible bacterium was M. flavus. The crude extract was found active on S. aureus ATCC 25923 and S. aureus Cowan I. The M. conica ethanol extract did not exhibit anticandidal activity against C. albican

Free-radical scavenging capacity and antimicrobial activity of wild edible mushroom from Turkey

Antioxidant capacity and antimicrobial activities of Ramaria flava (Schaeff) Quel. (RF) extracts obtained with ethanol were investigated in this study. Four complementary test systems; namely DPPH freeradical scavenging, -carotene/linoleic acid systems, total phenolic compounds and total flavonoid concentration have been used. Inhibition values of R. flava extracts, BHA and -tocopherol standardswere found to be 94.7, 98.9 and 99.2%, respectively, at 160ƒÊg/ml. When compared the inhibition levels of ethanol extract of R. flava and standards in linoleic acid system, it was observed that the higher theconcentration of both RF ethanol extract and the standards the higher the inhibition effect. Total flavonoid amount was 8.27}0.28 ƒÊg mg-1 quercetin equivalent while the total phenolic compound amountwas 39.83}0.32 ƒÊg mg-1 pyrocatechol equivalent in the ethanolic extract. The ethanol extract of R. flava inhibited the growth of Gram-positive bacteria better than Gram-negative bacteria and yeast. The crude extract showed no antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Morganella morganii and Proteus vulgaris. The antimicrobial activity profile of R. flava against tested strains indicated that Micrococcus flavus, Micrococcus luteus and Yersinia enterocolitica was the most susceptible bacteria of all the test strains. R. flava was found to be inactive against Candida albicans

Size-dependent nonlinear secondary resonance of micro-/nano-beams made of nano-porous biomaterials including truncated cube cells

Porous biomaterials have been utilized in cellular structures in order to mimic the function of bone as a branch of tissue engineering approach. With the aid of nanoporous biomaterials in which the pore size is at nanoscale, the capability of biological molecular isolation becomes more efficient. In the present study, firstly the mechanical properties of nanoporous biomaterials are estimated on the basis of a truncated cube cell model including a refined hyperbolic shear deformation for the associated lattice structure. After that, based upon a nonlocal strain gradient beam model, the size-dependent nonlinear secondary resonance of micro/nano-beams made of the nanoporous biomaterial is predicted corresponding to the both of subharmonic and superharmonic excitations. The non-classical governing differential equation of motion is constructed via Hamilton's principle. By employing the Galerkin technique together with the multiple time-scales method, the nonlocal strain gradient frequency-response and amplitude-response of the nonlinear oscillation of micro/nano-beams made of a nanoporous biomaterial under hard excitation are achieved. It is shown that in the superharmonic case, increasing the pore size leads to enhance the nonlinear hardening spring-type behavior of jump phenomenon and the height of limit point bifurcations. In the subharmonic case, higher pore size causes to increase the gap between two branches associated with the high-frequency and low-frequency solutions

Antioxidant and antimicrobial activity of russula delica fr: an edidle wild mushroom

Antioxidant capacity and antimicrobial activities of Russula delica Fr. (RD) extracts obtained with ethanol were investigated in this study. Four complementary test systems, namely DPPH free radical scavenging, beta-carotene/linoleic acid systems, total phenolic compounds and total flavonoid concentration, have been used. It was observed that inhibition values of both RD ethanolic extract and the standards (BHA and alpha-tocopherol) increased in parallel with the elevation of concentration in linoleic acid system. Total flavonoid amount was 8.71 +/- 0.56 mu g mg(-1) quercetin equivalents while the phenolic compound amount was 47.01 +/- 0.29 mu g mg-1 pyrocatechol equivalents in the extract. The antimicrobial activity of RD extract was tested in vitro by using the agar-well diffusion method. In our study, the RD extract showed antibacterial activity against. The RD extract did not exhibit anticandidal activity against Candida albicans. Therefore, the extracts could be suitable as antimicrobial and antioxidative agents in the food industry

patient-based survey

Although gout is potentially curable, the management of this disease is often suboptimal. In this study, we investigated the treatment of gout in Turkey and also compared the management approaches to gout in different clinical specialties. Three hundred and nineteen consecutive patients (mean age 58.60 +/- 12.8 years; 44 females, 275 males) were included in this multicenter study. A standardized form was generated to collect data about the patient's first admission to health care, the specialty of the doctor first diagnosed the gout, the treatment options for gout including attack management, patient referral, chronic treatment including medical treatment, and life style modifications. Forty patients were referred to another center without any treatment (12.8 %), and referral rate is most common among the primary care physicians (28.8 %). Colchicine was more commonly used for attack prophylaxis than allopurinol. Ninety-two patients had never been treated with allopurinol (28.8 %). Allopurinol prescription was less common among the primary care physicians and orthopedists, and highest among the rheumatologists. Recommendation of diet and life style modifications was less common among the primary care physicians and orthopedists, and highest among the rheumatologists. The rates of life style modification recommendation and long-term allopurinol prescription were 83.7 and 77.6 %, respectively, among the rheumatologists. Both acute and chronic management of gout is suboptimal in Turkey especially among the primary care physicians and orthopedists. Moreover, chronic treatment is even suboptimal among rheumatologists