71 research outputs found

    Alterations in biochemical profiles of patients with severe COVID-19 pneumonia: Analysis of repeated laboratory tests

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    Objective: This study was initiated to show the changes in the biochemical profile and identify the mortality risk factors of patients with severe coronavirus disease-19 (COVID-19) pneumonia. Materials and Methods: This study was designed as non-interventional and cohort research. Demographic and clinical data were retrospectively obtained from paper-based documents and electronic health records. Complete blood counts, inflammatory markers, liver, and kidney function tests, and coagulation profiles were recorded 3 times. Two-way ANOVA for repeated measures was used to analyze for continuous dependent variables. Binary logistic regression analysis was performed to determine in-hospital mortality risk factors. Results: Two hundred and fifty-two adult patients with severe COVID-19 pneumonia enrolled in our study – 15.8% of patients died during hospitalization. The mortality rate was 57.5% for those over 65 years of age. 61.9% of patients had at least one coexisting disease. We revealed hemoglobin, leukocyte, lymphocyte, platelet, C-reactive protein, procalcitonin, d-dimer, aspartate aminotransferase, and alanine aminotransferase, lactate dehydrogenase, creatinine, and ferritin were significantly changing within the time and also between survivors and non-survivors. Conclusion: The study showed that blood cell counts, coagulation profiles, liver and kidney function tests, and inflammatory markers deteriorated in non-survivor COVID-19 patients. Patients with shortness of breath, history of congestive heart failure, coronary artery disease, dementia, chronic renal disease, higher Charlson comorbidity index score, the need for invasive mechanic ventilation, presence of acute respiratory distress syndrome, and intensive care unit admission are more vulnerable to death

    Meten van klimaat in varkensstallen

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    Landslide initiation and runout susceptibility modeling in the context of hill cutting and rapid urbanization: a combined approach of weights of evidence and spatial multi-criteria

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    Rainfall induced landslides are a common threat to the communities living on dangerous hill-slopes in Chittagong Metropolitan Area, Bangladesh. Extreme population pressure, indiscriminate hill cutting, increased precipitation events due to global warming and associated unplanned urbanization in the hills are exaggerating landslide events. The aim of this article is to prepare a scientifically accurate landslide susceptibility map by combining landslide initiation and runout maps. Land cover, slope, soil permeability, surface geology, precipitation, aspect, and distance to hill cut, road cut, drainage and stream network factor maps were selected by conditional independence test. The locations of 56 landslides were collected by field surveying. A weight of evidence (WoE) method was applied to calculate the positive (presence of landslides) and negative (absence of landslides) factor weights. A combination of analytical hierarchical process (AHP) and fuzzy membership standardization (weighs from 0 to 1) was applied for performing a spatial multi-criteria evaluation. Expert opinion guided the decision rule for AHP. The Flow-R tool that allows modeling landslide runout from the initiation sources was applied. The flow direction was calculated using the modified Holmgren’s algorithm. The AHP landslide initiation and runout susceptibility maps were used to prepare a combined landslide susceptibility map. The relative operating characteristic curve was used for model validation purpose. The accuracy of WoE, AHP, and combined susceptibility map was calculated 96%, 97%, and 98%, respectively

    Landslide Susceptibility Mapping Using GIS-based Information Value and Frequency Ratio Methods in Gindeberet area, West Shewa Zone, Oromia Region, Ethiopia

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    Abstract The study area is found in Gindeberet district of West Shewa zone in Oromia Regional State of Ethiopia.This area is highly susceptible to active surface processes due to the presence of rugged morphology with steep scarps, sharp ridges, cliffs, deep gorges and valleys. This study aimed to identify and evaluate the causative factors and to prepare the landslide susceptibility maps (LSMs) of the study area. Two bivariate statistical models i.e. Information value(IV) and the Frequency ratio(FR), were used. First, active, reactivated and passive landslides and scarps were identified using Google Earth image interpretation and extensive field survey for landslide inventory. A total of 580 landslide were randomly selected into two datasets in which (80%)460 landslides were used for modeling and (20%)116 landslidesfor validation. conditioning factors (slope, aspect, curvature, distance from stream, distance from lineaments, lithology, rainfall and land use) were combined with a training landslide dataset in a ArcGIS to generate LSMs which weredivided into verylow, low, moderate, high and veryhigh susceptibility zones. LSMs for IV and FR models were validated using the Area under(ROC) curve showing a success rate of 0.836 and 0.835 respectively and a predictive rate of 0.817 and 0.818 respectively wich showed a good performance of both models. The resulting LSMs can be used for land use planning and management.</jats:p

    Weights of Evidence Modeling for Landslide Susceptibility Mapping of Kabi-Gebro Locality, Gundomeskel area, Central Ethiopia

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    Abstract Kabi-Gebro area is located within the Abay Basin at Dera District of North Shewa Zone near Gundomeskel town in the Central highland of Ethiopia and it is about 320 Km from Addis Ababa. This is characterized by undulating topography, intense rainfall, active erosion and highly cultivated area. Geologically characterized by weathered sedimentary and volcanic rocks. Currently, landslides are creating serious challenges in road construction, farming practices and affecting people in this area. Active landslides in this area damaged the gravel road, houses and agricultural land. The main objective of this research is to prepare the landslide susceptibility map. To overcome the landslide problem in this area, landslide susceptibility map was prepared using GIS- based Weights of Evidence model. Based on detailed field assessment and Google Earth image interpretation, 514 landslide locations were identified and classified randomly as training landslide (80%) and validation landslide (20%). The training landslide data set include nine landslide causative factors such as lithology, slope angle, aspect, curvature, land use/land cover, distance to stream, distance to lineament, distance to spring and rainfall inorder to prepare landslide susceptibility map in this study. The landslide susceptibility maps were prepared by adding the weights of contrast values of the nine causative factors using rater calculator in the spatial analyst tool of ArcGIS. The final landslide susceptibility map was reclassified as very low, low, moderate, high and very high landslide susceptiblity classes. This susceptibility map was validated using landslide density index and Area Under the Curve (AUC). The result from this validation showed a success rate and avalidaton rate accuracies of 82.4% and 83.4% respectively for this model. Finally, this study recommends application of appropriate mitigation or corrective measures in order to lessen the impact of landslide in the area.</jats:p

    Stability analysis of rock slope along selected road sections from Gutane Migiru town to Fincha sugar factory, Oromiya, Ethiopia

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    AbstractThe slope instability was one of the common problems along the road that connects Gutane Migiru town to Fincha sugar factory, Western Ethiopia. The effect of the problem was intense mostly; during the rainy season, that triggers different modes of rock slope failure. As a result, the road was frequently damaged and blocked by the failed rock that in turn hinders the traffic activities. Thus, this study aimed at stability analyses of the critical slope sections using kinematic and limit equilibrium methods (LEM). The estimation of the most important input parameter in LEM analyses like cohesion and friction angle along the failure plane is often intricate and cumbersome. Hence, this paper used Rocscience software to effortlessly and instantly compute cohesion and friction angle along specific failure planes and then to carry out kinematic and LEM analyses. Besides, the strength of the intact rock was determined by the Schmidt hammer in the field and point load laboratory test. According to the kinematic analysis result, the wedge mode of rock slope failure occurred at slope sections D1S2 and D1S3 though the planar mode of failure occurred at slope sections D1S4 and D4S1. The factor of safety determined under all anticipated conditions became less than and greater than one at slope sections D1S2, D1S3, D1S4, and D4S1, and this depicts an unstable and stable slope, respectively. From the analysis result, the combined effect of rainfall, steepness of the slope dip, and joint set was the main factors that caused the slope insatiability.</jats:p

    Frequency Ratio Density, Logistic Regression and Weights of Evidence Modelling for Landslide Susceptibility Assessment and Mapping in Yanase and Naka Catchments of Southeast Shikoku, Japan

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    Abstract Landslide susceptibility mapping is an important tool for disaster management and development activities such as planning of transportation infrastructure, settlement and agriculture. Shikoku Island, which is found in the southwest of Japan, is one of the most landslide prone areas because of heavy typhoon rainfall, complex geology and the presence of mountainous areas and low topographic features (valleys).Yanase and Naka Catchments of Shikoku Island in Japan were chosen as a study area. Frequency Ratio Densisty (FRD), Logistic Regression (LR) and Weights of Evidence (WoE) models were applied in a GIS environment to prepare the landslide susceptibility maps of this area. Data layers including slope, aspect, profile curvature, plan curvature, lithology, land use, distance from river, distance from fault and annual rainfall were used in this study. In FR method, two models were attempted but the FRD model was found slightly better in its performance. In case of LR method, two models, one with equal proportion and the other with unequal proportion of landslide and non-landslide points were carried out and the one with equal proportions was chosen based on its highest performance. A total of five landslide susceptibility maps(LSMs) were produced using FR, LR and WoE models with two, two and one were attempted respectively. However, one best model was chosen from the FR and LR methods based on the highest area under the curve (AUC) of the receiver operating characteristic (ROC) curves. This reduced the total number of landslide susceptibility maps to three with the success rates of 86.7%, 86.8% and 80.7% from FRD, LR and WoE models respectively. For validation purpose, all landslides were overlaid over the three landslide susceptibility maps and the percentage of landslides in each susceptibility class was calculated. The percentages of landslides that fall in the high and very high susceptibility classes of FRD, LR and WoE models showed 82%, 84% and 78% respectively. This showed that the LR model with equal proportions of landslides and non-landslide points is slightly better than FRD and WoE models in predicting the future probability of landslide occurrence.</jats:p
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