Eine Auseinandersetzung mit Suizidalität: wissen der Sozialen Arbeit und ausgewählten Bezugsdisziplinen, welches Sozialarbeitende als hilfreich erleben

In der vorliegenden Arbeit wird in einem ersten Teil das Wissen aus der Sozialen Arbeit und aus ausgewählten Bezugsdisziplinen aufgearbeitet, das für Sozialarbeitende bei Klientenmandaten im Kontext von Suizidalität wichtig ist. In einem zweiten Teil wird in einer qualitativen Erhebung erfasst, welches Wissen um Suizidalität Sozialarbeitende in der Praxis als hilfreich erleben. Die theoretischen Grundlagen betreffen den Gegenstand Suizid sowie dessen Relevanz in der Sozialen Arbeit, das zur Verfügung stehende Wissen ausgewählter Bezugsdisziplinen und die Bedeutung der interdisziplinären Zusammenarbeit. Mit Blick auf die Praxis der Sozialen Arbeit sind die zentralen Anliegen dieses Teils: Wissen zum Erhalt der Handlungsfähigkeit im Kontext von Suizid erarbeiten, die zum methodischen Handeln nötigen Wissensbestände kontextual zu beschreiben und die ethisch-moralische Dimension des sozialarbeiterischen Handels diskutieren

Temperature-dependent tonic contraction of smooth muscle in Antarctic fishes Notothenia neglecta and Chaenocephalus aceratus - Role of calcium ions and responses to acetylcholine

The isolated intestinal smooth muscle of Antarctic fishes Notothenia neglecta and the icefish Chaenocephalus aceratus displayed a sustained tonic contraction depending upon the temperature of the nutritive bath. The contraction was maximal at 2℃, relaxing proportionally with rise of the temperature, from 2℃ to 18℃. The contractile responses to acetylcholine gradually increased in proportion to the rise of temperature. By chelating calcium ions, EDTA caused a reversible relaxation of the contracted muscle at 2.0℃. This effect was eliminated by washing out the drug from the muscle nutritive bath. Similar results were found with the administration of verapamil, a calcium channel blocker. However, after this drug, tonic contraction was not restored by washout. Such contraction was partially inhibited by the muscarinic blocking drug atropine. Results show that the tonic contraction is an active response, dependent on the entry of calcium into the cell and mediated by cholinergic receptors. The temperature-related tonic contraction is not a general event in poikilotherm animals, since it did not occur in the Bufo marinus intestinal smooth muscle, in similar experiments carried out as a control, in a tropical environment. The responsiveness of the smooth muscle to acetylcholine appeared to increase with temperature, suggesting lack of adaptation of the organ to low Antarctic temperature

A girl with sternal malformation/vascular dysplasia association

Sternal malformation/vascular dysplasia association is a rare congenital dysmorphology, which has not yet been reported in Korea. Its typical clinical features include a sternal cleft covered with atrophic skin, a median abdominal raphe extending from the sternal defect to the umbilicus, and cutaneous craniofacial hemangiomata. We report a case of a full-term newborn who presented with no anomalies at birth, except for a skin defect over the sternum and a supraumbilical raphe. Multiple hemangiomas appeared subsequently on her chin and upper chest wall, and respiratory distress due to subglottic hemangioma developed during the first 2 months of life. Her symptoms were controlled with oral prednisolone administration. No respiratory distress have recurred during the 3-year follow-up period

KNOX Community Gardens: Growing Crops and Social Capital among Urban Gardeners in Hartford

Utilizing Hartford’s green space defined the original mission statement of KNOX. Over the past 50 years, however, KNOX has transformed into an organization that ranges from providing youth with job skills, to growing new urban gardens, to connecting people for the purpose of lowering social barriers and effecting change. Urban scholars note the power of “social capital” to increase opportunities for community activism. Strengthening a community’s social networks makes bridging differences and creating a sense of common purpose possible. We therefore ask the question: Is KNOX utilizing its gardens in the most effective way to increase the social capital of Hartford gardeners and neighborhoods? To answer this question I conducted two semi-structured interviews with community gardeners, 10 semi-structured surveys with KNOX employees, and produced a firsthand description of each garden location. There are currently twenty-two KNOX community gardens and five new gardens in the works. The goals for these gardens should be expanded to incorporate social capital goals, in order to realize the potential for community gains that could not otherwise be achieved. The success of this project depends on the ability to measure the social capital KNOX community gardens are providing now, and identify ways to increase it in the future

Aspectos bioquímicos do metabolismo de carboidratos em Biomphalaria glabrata

The article has no abstract.Biomphalaria glabrata apresenta grande capacidade para metabolizar carboidratos, além de mecanismo ativo de biossíntese de carboidratos. Sabe-se que o conteúdo total de carboidratos que oscila entre 12-14% no peso total do organismo varia de acordo com condições específicas nas quais vive o molusco, por exemplo, durante períodos de jejum ou em condições de vida fora d’água. Mecanismo anaplerótico especial pode ser associado com os principais padrões biossintéticos do metabolismo de carboidratos, isto é, a operação da enzima “málica”. Essa última pode ser associada aos mecanismos respiratórios através do ciclo do TCA ou com a via significativa para a reoxidação do NADH formado durante a glipiruvato. B. glabrata é também muito peculiar no que se refere à regulação de níveis de NADP/NADPH e NAD/NADH, esse último sendo regulado pela desidrogenase de α-glicerofosfato de pé muscular, enquanto que a atividade de desidrogenase láctica é menos significativa para a reoxidação do NADH formado durante a glicólise. Além disso, foi ainda verificado que os tentáculos isolados de B. glabrata são capazes de mobilidade unidirecional na água. Tal mobilidade pode ser medida e usada como reagente biológico sensível para o estudo do efeito biológico de inibidores metabólicos e de moluscocidas e uma variedade de compostos quimoterapêuticos usados no tratamento da esquisostomose mansônica. A antena isolada é também muito sensível à ação de vários agentes farmacológicos

In vitro cultures of Silybum marianum and silymarin accumulation

AbstractIn this study, a protocol for initiation of callus and shoot cultures from leaves and shoot tips explants of different silybium genotypes collected from different locations in Egypt was established. Callus cultures were initiated from leaves explants and exposed to different concentrations of the precursor (coniferyl alcohol). Shoot cultures were initiated from shoot tips explants. Moreover, the produced plants of the different Silybium shoots as well as intact plants were subjected to protein screening using SDS–PAGE analysis.Results obtained revealed that the optimum medium for growth and maintenance of friable callus was MS medium supplemented with 0.25mgL−1 2,4-Dichlorophenoxy acetic acid (2,4-D)+0.25mg L−1 Kinetin (Kin). The best medium for proliferation of high number of shoots was MS-medium with 0.25mgL−1 each of Benzyl Adinine (BA) and Naphthalene Acetic Acid (NAA). Coniferyl alcohol in concentration of 30μM caused an increase in accumulation of silymarin contents in most callus cultures. SDS–PAGE of different Silybium shoots revealed that the protein profiles of 100% of in vitro produced plantlets similar to their control

Neurodevelopmental abnormalities in children with PHACE syndrome.

Prior case reports have identified neurodevelopmental abnormalities in children with PHACE syndrome, a neurocutaneous disorder first characterized in 1996. In this multicenter, retrospective study of a previously identified cohort of 93 children diagnosed with PHACE syndrome from 1999 to 2010, 29 children had neurologic evaluations at ≥ 1 year of age (median age: 4 years, 2 months). In all, 44% had language delay, 36% gross motor delay, and 8% fine motor delay; 52% had an abnormal neurological exam, with speech abnormalities as the most common finding. Overall, 20 of 29 (69%) had neurodevelopmental abnormalities. Cerebral, but not posterior fossa, structural abnormalities were identified more often in children with abnormal versus normal neurodevelopmental outcomes (35% vs. 0%, P = .04). Neurodevelopmental abnormalities in young children with PHACE syndrome referred to neurologists include language and gross motor delay, while fine motor delay is less frequent. Prospective studies are needed to understand long-term neurodevelopmental outcomes