Three-D crater analysis of LDEF impact features from stereo imagery

The preliminary results from attempts to derive depth and diameter information from digitized stereo images of impact features on the LDEF are reported. Contrary to our prior assumption, we find that impact craters in the T6 A1 alloy are not paraboloid in cross section, but rather are better described by a 6th-order polynomial curve. We explore the implications of this discovery

Continued investigation of LDEF's structural frame and thermal blankets by the Meteoroid and Debris Special Investigation Group

This report focuses on the data acquired by detailed examination of LDEF intercostals, 68 of which are now in possession of the Meteoroid and Debris Special Investigation Group (M&D SIG) at JSC. In addition, limited data will be presented for several small sections from the A0178 thermal control blankets that were examined/counted prior to being shipped to Principal Investigators (PI's) for scientific study. The data presented here are limited to measurements of crater and penetration-hole diameters and their frequency of occurrence which permits, yet also constrains, more model-dependent, interpretative efforts. Such efforts will focus on the conversion of crater and penetration-hole sizes to projectile diameters (and masses), on absolute particle fluxes, and on the distribution of particle-encounter velocities. These are all complex issues that presently cannot be pursued without making various assumptions which relate, in part, to crater-scaling relationships, and to assumed trajectories of natural and man-made particle populations in LEO that control the initial impact conditions

Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania.

To compare the presence and quantity of cervicovaginal HIV among HIV seropositive women with clinical herpes, subclinical HSV-2 infection and without HSV-2 infection respectively; to evaluate the association between cervicovaginal HIV and HSV shedding; and identify factors associated with quantity of cervicovaginal HIV. Four groups of HIV seropositive adult female barworkers were identified and examined at three-monthly intervals between October 2000 and March 2003 in Mbeya, Tanzania: (1) 57 women at 70 clinic visits with clinical genital herpes; (2) 39 of the same women at 46 clinic visits when asymptomatic; (3) 55 HSV-2 seropositive women at 60 clinic visits who were never observed with herpetic lesions; (4) 18 HSV-2 seronegative women at 45 clinic visits. Associations of genital HIV shedding with HIV plasma viral load (PVL), herpetic lesions, HSV shedding and other factors were examined. Prevalence of detectable genital HIV RNA varied from 73% in HSV-2 seronegative women to 94% in women with herpetic lesions (geometric means 1634 vs 3339 copies/ml, p = 0.03). In paired specimens from HSV-2 positive women, genital HIV viral shedding was similar during symptomatic and asymptomatic visits. On multivariate regression, genital HIV RNA (log10 copies/mL) was closely associated with HIV PVL (β = 0.51 per log10 copies/ml increase, 95%CI:0.41-0.60, p<0.001) and HSV shedding (β = 0.24 per log10 copies/ml increase, 95% CI:0.16-0.32, p<0.001) but not the presence of herpetic lesions (β = -0.10, 95%CI:-0.28-0.08, p = 0.27). HIV PVL and HSV shedding were more important determinants of genital HIV than the presence of herpetic lesions. These data support a role of HSV-2 infection in enhancing HIV transmissibility

Measuring the Higgs Sector

If we find a light Higgs boson at the LHC, there should be many observable channels which we can exploit to measure the relevant parameters in the Higgs sector. We use the SFitter framework to map these measurements on the parameter space of a general weak-scale effective theory with a light Higgs state of mass 120 GeV. Our analysis benefits from the parameter determination tools and the error treatment used in new--physics searches, to study individual parameters and their error bars as well as parameter correlations.Comment: 45 pages, Journal version with comments from refere

Hadron Spectroscopy: Theory and Experiment

Many new results on hadron spectra have been appearing in the past few years thanks to improved experimental techniques and searches in new channels. New theoretical techniques including refined methods of lattice QCD have kept pace with these developments. Much has been learned about states made of both light (u, d, and s) and heavy (c, b) quarks. The present review treats light-quark mesons, glueballs, hybrids, particles with a single c or b quark, charmonium, and bottomonium states. Some prospects for further study are noted.Comment: 29 pages, 9 figures, to be published in Journal of Physics G. Further updating of reference

Moduli Stabilization from Fluxes in a Simple IIB Orientifold

We study novel type IIB compactifications on the T^6/Z_2 orientifold. This geometry arises in the T-dual description of Type I theory on T^6, and one normally introduces 16 space-filling D3-branes to cancel the RR tadpoles. Here, we cancel the RR tadpoles either partially or fully by turning on three-form flux in the compact geometry. The resulting (super)potential for moduli is calculable. We demonstrate that one can find many examples of N=1 supersymmetric vacua with greatly reduced numbers of moduli in this system. A few examples with N>1 supersymmetry or complete supersymmetry breaking are also discussed.Comment: 49 pages, harvmac big; v2, corrected some typo

RS1, Custodial Isospin and Precision Tests

We study precision electroweak constraints within a RS1 model with gauge fields and fermions in the bulk. The electroweak gauge symmetry is enhanced to SU(2)_L \times SU(2)_R \times U(1)_{B-L}, thereby providing a custodial isospin symmetry sufficient to suppress excessive contributions to the T parameter. We then construct complete models, complying with all electroweak constraints, for solving the hierarchy problem, without supersymmetry or large hierarchies in the fundamental couplings. Using the AdS/CFT correspondence our models can be interpreted as dual to a strongly coupled conformal Higgs sector with global custodial symmetry, gauge and fermionic matter being fundamental fields external to the CFT. This scenario has interesting collider signals, distinct from other RS models in the literature.Comment: 32 pages, 6 figures, latex2e, minor changes, references adde

Of Bounces, Branes and Bounds

Some recent studies have considered a Randall-Sundrum-like brane world evolving in the background of an anti-de Sitter Reissner-Nordstrom black hole. For this scenario, it has been shown that, when the bulk charge is non-vanishing, a singularity-free ``bounce'' universe will always be obtained. However, for the physically relevant case of a de Sitter brane world, we have recently argued that, from a holographic (c-theorem) perspective, such brane worlds may not be physically viable. In the current paper, we reconsider the validity of such models by appealing to the so-called ``causal entropy bound''. In this framework, a paradoxical outcome is obtained: these brane worlds are indeed holographically viable, provided that the bulk charge is not too small. We go on to argue that this new finding is likely the more reliable one.Comment: 15 pages, Revtex; references added and very minor change

Is There A String Theory Landscape

We examine recent claims of a large set of flux compactification solutions of string theory. We conclude that the arguments for AdS solutions are plausible. The analysis of meta-stable dS solutions inevitably leads to situations where long distance effective field theory breaks down. We then examine whether these solutions are likely to lead to a description of the real world. We conclude that one must invoke a strong version of the anthropic principle. We explain why it is likely that this leads to a prediction of low energy supersymmetry breaking, but that many features of anthropically selected flux compactifications are likely to disagree with experiment.Comment: 39 pages, Latex, ``Terminology surrounding the anthropic principle revised to conform with accepted usage. More history of the anthropic principle included. Various references added.

Analysis of noise in differential and ratiometric biosensing systems

This paper presents formulations to evaluate noise in differential and ratiometric measurements that are often performed in biosensing. These measurements are performed to improve signal to noise ratio of the sensing systems for sensitive detection of dynamic biological processes. The use of these formulations is discussed in the context of the differential intensity surface plasmon resonance (SPR) system that is widely used to characterise molecular interactions on a confined axial scale. Previous studies provide qualitative descriptions of the noise performance of such systems but lack rigorous characterisation. Here we present analytical expressions for quantitative evaluation of the noise in differential and ratiometric measurements by applying the rules of arithmetic operations on random variables. Such formulations provide the means for evaluating the signal to noise ratio of such systems. We present how correlated noise can be removed by performing differential or ratiometric processing. Applying these formulations, we also show how the sensitivity of the differential intensity SPR system changes during the experiment