Entwickeln sich wirtschaftswissenschaftliche Forschung und Politikberatung auseinander?

Ökonomen und Politiker beklagen sich gelegentlich übereinander. Die Ökonomen meinen, das politische Alltagsgeschäft berücksichtige die Erkenntnisse der Wissenschaft zu wenig und sei mit inkonsistenten Maßnahmen und suboptimalen Ergebnissen verbunden. Die Politiker sehen sich dagegen zum Teil mit realitätsfernen Empfehlungen konfrontiert. Die Bewertungsschemata für wissenschaftliche Exzellenz schaffen zudem Anreize für eher theoretisch ausgerichtete Forschung. Eine solch dramatische Diskrepanz zwischen Politikberatung und Forschung können die Autoren dieses Zeitgesprächs in der Regel nicht erkennen.Most German economists show strong patterns of professional specialisation. In their work, they either focus on basic research or on policy consultancy. The evidence provided by Haucap und Mödl has been used to question work incentives in academia. The suggestion to change work incentives, however, is not supported by Richter, who rather calls into question the German tradition of research funding. He argues that Germany should devote more competitive funding to research projects and less to institutions. Schmidt et al. explore the question the other way around: do policy consultants publish in top journals? They conclude that they do. Güth/Kliemt show how precarious and limited our (technologically useful) knowledge is. The discussion of alternative policies among economic experts should be used to tease out the controversial arguments to allow for better informed political judgements. Wagner/Fratzscher take a historical view, showing that when modern economic research (and economic research institutes) apply a more pluralistic paradigm than that which prevailed in Germany for a long period after the Second World War, economic research will automatically have a more significant impact on politics, since policy advisors will produce more varied advice with the potential for realisation. Koll also claims that policy advice must not be based on a single supply-side oriented mainstream point of view. By drawing lessons from the crisis, economics must identify a new mainstream providing reliable guidance and policy advice

First age- and gender-matched case-control study in Australia examining the possible association between toxoplasma gondii Infection and type 2 diabetes mellitus: The Busselton Health Study

An emerging field of research is starting to examine the association of infectious pathogens with type 2 diabetes mellitus (T2DM). An understudied parasite of interest is Toxoplasma gondii. Globally, very few studies have been conducted to investigate this association. Additionally, very little data exists on the prevalence of T. gondii in the general Australian population. Our group sought to determine the prevalence, association, and risk factors between T. gondii infection and T2DM from a representative Australian human population. Through a cross-sectional, age-A nd gender-matched case-control study, 150 subjects with T2DM together with 150 control subjects from the Busselton Health Study cohort were investigated. Sera samples were tested for the presence of anti-T. gondii IgG and IgM antibodies using enzyme-linked immunosorbent assays. Survey-derived data were also analyzed to evaluate associated risk factors. The IgG seroprevalence was found to be 62% and 66% for the T2DM and control groups, respectively (OR:0.84; p=0.471). IgM antibodies were detected in 5% of the T2DM patients and in 10% of the controls (OR=0.51; p=0.135). There were no significant differences between male and female IgG seroprevalence rates for both groups (OR:0.88, 0.80; p=0.723). The IgG seropositivity rate increased significantly in T2DM patients aged 45-84 years in comparison to those aged 18-44 years (p\u3c 0.05), but this was not observed in the control subjects. No risk factors were associated with T. gondii seropositivity in both groups. The first Australian study of its kind found T. gondii infection in Western Australia to be highly prevalent. The results also showed that there is no serological evidence of an association between T. gondii infection and T2DM in the studied subjects. Australian health authorities should focus on raising awareness of toxoplasma infection and target T. gondii transmission control. Further studies are needed to clarify the role of T. gondii in T2DM. © 2020 Aus Molan et al

Prevalence of toxoplasmic retinochoroiditis in an Australian adult population: A community-based study

Purpose: Toxoplasmic retinochoroiditis is the most common clinical manifestation of an infection with the protozoan parasite, Toxoplasma gondii. Up to 50 % of the human population is estimated to be infected with T. gondii; however, the epidemiology of toxoplasmic retinochoroiditis has not been widely reported. We sought to estimate the prevalence of toxoplasmic retinochoroiditis in Australia using data that were collected as part of the Busselton Healthy Ageing Study. Design: oss-sectional, community-based, prospective cohort study. Participants: 5020 Australian adults (2264 men and 2756 women; age range, 45–69 years, and median age, 58 years). Methods : Retinal color photographs, centered on the optic disc and macula, were captured using a digital retinal camera after the dilation of the pupils. Three uveitis-subspecialized ophthalmologists assessed each pigmented retinal lesion, and complete concordance of opinion was required to assign a toxoplasmic etiology. Serum T. gondii immunoglobulin (Ig)G levels were measured for those participants with retinal lesions judged to be toxoplasmic retinochoroiditis. Main Outcome Measures : Prevalence of toxoplasmic retinochoroiditis. Results: Eight participants (0.16 %) had retinal lesions that were considered to have the characteristic appearance of toxoplasmic retinochoroiditis, plus detectable serum T. gondii IgG, consistent with the diagnosis of toxoplasmic retinochoroiditis. On the assumption that 23.81 % of retinal lesions occur at the posterior pole, as reported in a community-based survey conducted in Brazil (Sci Rep. 2021;11:3420), the prevalence of toxoplasmic retinochoroiditis was estimated to be 0.67 % or 1 per 149 persons. Conclusions: Toxoplasmic retinochoroiditis is common in Australian adults. Efforts to quantify and address risk factors for human infection with T. gondii are justified

Cyclisch konjugierte 5- und 7-Ringsysteme, IV. Notiz über die Synthese des 8-Acetylheptafulvens

Acetonyl-1,3,5-cycloheptatrien (1) läßt sich durch Hydrid-Abstraktion mit Triphenylmethyliumperchlorat in das Acetonyltropyliumperchlorat (4) überführen, aus dem durch Deprotonierung mit Triethylamin das 8-Acetylheptafulven (5) erhalten wird. Dieses reagiert mit Acetylendicarbonsäure-dimethylester in einer [8 + 2]-Cycloaddition und nachfolgender Dehydrierung zum 3-Acetyl-1,2-azulendicarbonsäure-dimethylester (6)

Shifting the Burden of Corporate Taxes Heterogeneity in Direct Wage Incidence

We contribute to the empirical literature on the effective incidence of corporate income taxation. We focus on the so-called direct incidence via the wage bargaining process. Building on the innovative framework of Arulampalam, Devereux and Maffini (2012), we analyze the importance of various dimensions of heterogeneity at the firm-level. In particular, we investigate the distinct effects of (i) firm size, (ii) level of profitability, and (iii) competition intensity across (iv) different economic sectors. Furthermore, we investigate the relative importance of the surrounding institutional setting. To this end, a firm-level within-country approach is pursued separately for two different economies, namely France and the United Kingdom, which can be regarded as polar cases with respect to the relevant features of the wage-setting process. However, in many respects, we find surprisingly similar results for both countries. Thereby, this paper also adds to the literature by providing new insights on the degree to which results from previous single-country studies can possibly be generalized.Die effektive Inzidenz der Körperschaftsteuer ist ein theoretisch wie empirisch kontroverses Thema. Das Paper leistet einen Beitrag zur empirischen Literatur und fokussiert dabei auf die sogenannte direkte Inzidenz über den Lohnverhandlungskanal. Aufbauend auf dem innovativen Ansatz von Arulampalam, Devereux und Maffini (2012) wird die Bedeutung von verschiedenen Dimensionen der Heterogenität auf der Firmenebene analysiert. Konkret wird erforscht, welchen Einfluss (i) Firmengröße, (ii) Profitabilität und (iii) Wettbewerbsintensität in (iv) verschiedenen Branchen auf das Ausmaß ausüben, in dem die Last der Körperschaftsteuer auf die Löhne der Beschäftigten überwälzt wird. Darüber hinaus wird untersucht, welche Relevanz dabei den institutionellen Gegebenheiten der Lohnverhandlungen zukommt. Dazu werden alle Analysen separat für Frankreich und das Vereinigte Königreich vollzogen, deren Volkswirtschaften mit Blick auf Arbeitsmarktinstitutionen als polare Fälle gelten können. Die jeweiligen Ergebnisse für die beiden Länder sind sich jedoch qualitativ wie quantitativ überraschend ähnlich. Insofern gibt die Studie auch einen Hinweis darauf, inwiefern die Ergebnisse aus auf einzelne Länder bezogene Studien zur effektiven Lohninzidenz der Körperschaftsteuer generalisiert werden können

Effect of climate change on environmental flow indicators in the Narew Basin, Poland

Environmental flows—the quantity of water required to maintain a river ecosystem in its desired state—are of particular importance in areas of high natural value. Water-dependent ecosystems are exposed to the risk of climate change through altered precipitation and evaporation. Rivers in the Narew basin in northeastern Poland are known for their valuable river and wetland ecosystems, many of them in pristine or near-pristine condition. The objective of this study was to assess changes in the environmental flow regime of the Narew river system, caused by climate change, as simulated by hydrological models with different degrees of physical characterization and spatial aggregation. Two models were assessed: the river basin scale model Soil and Water Assessment Tool (SWAT) and the continental model of water availability and use WaterGAP. Future climate change scenarios were provided by two general circulation models coupled with the A2 emission scenario: IPSL-CM4 and MIROC3.2. To assess the impact of climate change on environmental flows, a method based conceptually on the “range of variability” approach was used. The results indicate that the environmental flow regime in the Narew basin is subject to climate change risk, whose magnitude and spatial variability varies with climate model and hydrological modeling scale. Most of the analyzed sites experienced moderate impacts for the Generic Environmental Flow Indicator (GEFI), the Floodplain Inundation Indicator, and the River Habitat Availability Indicator. The consistency between SWAT and WaterGAP for GEFI was medium: in 55 to 66% of analyzed sites, the models suggested the same level of impact. Hence, we suggest that state-of-the-art, high-resolution, global- or continental-scale models, such as WaterGAP, could be useful tools for water management decision-makers and wetland conservation practitioners, whereas models such as SWAT should serve as a complementary tool for more specific, smaller-scale, local assessments

The role of Toxoplasma gondii as a possible inflammatory agent in the pathogenesis of type 2 diabetes mellitus in humans

ype 2 diabetes mellitus (T2DM) continues to be a major challenge for public health authorities worldwide. While potential causes such as obesity, physical inactivity, and dietary patterns have been proposed to explain the growing epidemic, there may also be unidentified environmental determinants. An emerging field of research is starting to examine the association of infectious and environmental pathogens with diabetes. In particular, the potential of these pathogens to cause low-grade inflammation that facilitates the risk and development of T2DM. An understudied pathogen of potential interest is the protozoan parasite Toxoplasma gondii (T. gondii). There is limited clinical evidence supporting the association between chronic T. gondii infection and the development of many disorders, including T2DM, in both animals and humans. This review (1) addresses the existing knowledge of the role of T. gondii in the inflammation process leading to T2DM, (2) examines the current studies describing the relationship between T. gondii and T2DM, and (3) makes recommendations for future studies to determine the role of T. gondii in the pathogenesis of T2DM. We believe that T. gondii may be an important target for T2DM intervention, and propose a new field of study, “toxoplasmic type 2 diabetes.

The association between Toxoplasma gondii and type 2 diabetes mellitus: a systematic review and meta-analysis of human case-control studies

Abstract Objectives An emerging field of research is examining the association of infectious and environmental pathogens with type 2 diabetes mellitus (T2DM). An understudied pathogen of interest is the protozoan parasite Toxoplasma gondii (T. gondii). The objective of this study was to investigate the possible correlation between T. gondii infection and T2DM. We conducted a systematic review and meta-analysis on the currently available T. gondii seroprevalence data from case-control studies looking at subjects with T2DM in comparison to healthy controls to estimate the risk of T2DM. Methods Ten electronic databases were searched using specific Medical Subject Headings terms without language or date restrictions. Fixed and random effects models were used to determine odds ratios with statistical significance being set at 5.0%. Results Ten publications reporting T. gondii seroprevalence from 4072 subjects met the eligibility criteria. Seven of these studies reported a significant association between T. gondii infection and T2DM (p &lt; 0.05). The overall weighted prevalence of T. gondii infection in subjects with T2DM was 47.8% (range 6.4–65.1%) in comparison to 25.9% (range 3.2–59.0%) of healthy controls (p &lt; 0.001). The common odds ratio, calculated using a random effects model, was 2.32 (95% CI 1.66–3.24, p &lt; 0.001). Conclusions T. gondii infection should continue to be regarded as a possible contributing factor in T2DM disease development. Further studies that include inflammatory biomarker analysis are warranted to determine the specific role of this parasite in the pathogenesis of T2DM. </jats:sec