The Poetics of Dissolution: The Representation of Maori Culture in Janet Frame's Fiction

This essay examines Janet Frame's early short story "The Lagoon", and argues that the story alludes to Maori experience, albeit tangentially, in a way which anticipates similar evocations in novels such as A State of Siege and The Carpathians. A close reading shows that cultural imperialism in Frame runs parallel to, or is a side-effect of, interpersonal appropriations. These, in turn, seem to be rooted in human beings' reluctance to accommodate otherness. Recurrently Janet Frame points to a model of cultural and interpersonal interaction which is detached from proprietorial forms of appropriation, but which entails nothing less than the dissolution of the ruling ego. Selfdissolution shall emerge in this reading as the key to a utopian state consisting of the total permeability between the self and the remainder of the world. In this state, transactions become reciprocal since the divisions between self and non-self no longer exist

Simultaneous optical and radar observations of meteor head-echoes utilizing SAAMER

We present simultaneous optical and radar observations of meteors observed with the Southern Argentine Agile MEteor Radar (SAAMER). Although such observations were performed in the past using High Power and Large Aperture radars, the focus here is on meteors that produced head echoes that can be detected by a significantly less sensitive but more accessible radar system. An observational campaign was conducted in August of 2011, where an optical imager was operated near the radar site in Rio Grande, Tierra del Fuego, Argentina. Six head echo events out of 150 total detections were identified where simultaneous optical meteors could also be clearly seen within the main radar beam. The location of the meteors derived from the radar interferometry agreed very well with the optical location, verifying the accuracy of the radar interferometry technique. The meteor speeds and origin directions calculated from the radar data were accurate—compared with the optics—for the 2 meteors that had radar signal-to-noise ratios above 2.5. The optical meteors that produced the head echoes had horizontal velocities in the range of 29–91 km/s. These comparisons with optical observations improve the accuracy of the radar detection and analysis techniques, such that, when applied over longer periods of time, will improve the statistics of southern hemisphere meteor observations. Mass estimates were derived using both the optical and radar data and the resulting masses agreed well with each other. All were within an order of magnitude and in most cases, the agreement was within a factor of two.Facultad de Ciencias Astronómicas y Geofísica

Análisis bibliométrico de la aplicación de biomasas para la remoción de arsénico y plomo en aguas contaminadas

La búsqueda de materiales biodegradables, renovables y eficientes ha sido objeto de investigaciones encaminadas a reemplazar los materiales convencionales utilizados para reducir los impactos ambientales. La presente investigación tuvo como objetivo identificar los métodos más utilizados en la aplicación de biomasas para la remoción de arsénico y plomo en aguas contaminadas. La metodología fue de tipo aplicada, enfoque cuantitativo, diseño no experimental y nivel descriptivo. La información fue recopilada tanto de la base de datos Scopus como de Web of Science desde enero de 2010 hasta septiembre de 2020. El análisis de datos se llevó a cabo utilizando la herramienta VOSviewer. Se investigaron los principales países, áreas académicas, autores y tendencias de publicación en remoción de arsénico y plomo empleando biomasas en aguas contaminadas. Los resultados del estudio mostraron que las biomasas aspergillus niger y sorghum bicolor presentaron mayor capacidad de adsorción, alcanzando porcentajes de remoción de 89 y 98%, respectivamente con un tiempo de contacto de 24 horas y a pH 6. Finalmente, se concluye que la absorción e intercambio iónico son los métodos de tratamiento más empleados y son alternativa efectiva para la remoción de arsénico y plomo con biomasas de residuos orgánicos

Estrategias didácticas en el desarrollo de la inteligencia emocional.

PDFLa presente investigación se llevó a cabo con el objetivo analizar las estrategias didácticas que utilizan los docentes en el desarrollo de la inteligencia emocional de los estudiantes de la escuela de educación básica particular “Minerva”. El estudio adoptó una perspectiva cuantitativa cualitativa, utilizando métodos de observación y análisis, instrumentos como test, encuesta y entrevista de las prácticas educativas actuales. Los resultados obtenidos demostraron, que los maestros implementan actividades que desarrollan en mayor proporción ,para la escucha activa, resolución de conflictos, trabajo en equipo y habilidades de liderazgo, no así en la comunicación asertiva, empatía, desarrollo de la conciencia social, y la retroalimentación constructiva; por el contrario los estudiantes presentan un aprovechamiento emocional y autoconciencia aceptable, el autocontrol, la empatía y las habilidades sociales, requieren ser fortalecidas, lo que amerita fortalecerse a través de una guía didáctica .The present research was carried out with the objective of analyzing the teaching strategies used by teachers in the development of the emotional intelligence of the students of the “Minerva” private basic education school. The study adopted a qualitative quantitative perspective, using observation and analysis methods, instruments such as tests, surveys and interviews of current educational practices. The results obtained demonstrated that teachers implement activities that they develop in a greater proportion for active listening, conflict resolution, teamwork and leadership skills, but not in assertive communication, empathy, development of social awareness, and constructive feedback; On the contrary, students present emotional development and acceptable self-awareness, self-control, empathy and social skills, which require strengthening through a didactic guid

Evaluación del comportamiento de vigas en voladizo de concreto reforzado con fibras metálicas ante cargas dinámicas

Este estudio presenta algunos de los efectos que tiene la adición de fibras metálicas en el comportamiento dinámico de vigas en voladizo de concreto reforzado. Para esto, se construyeron dos especímenes de control, elaborados con concreto convencional, para tener como punto de referencia. Además de esto, se contó con cuatro especímenes más, dos con adiciones de fibras metálicas de 15 kg/m3 y dos más de 30 kg/m3, todas las probetas se sometieron a ensayos pseudo-dinámicos a partir de los cuales fue posible realizar comparaciones acerca del desempeño sísmico histerético de las diferentes vigas. Con base en estos resultados, se encontró que las fibras metálicas mejoran el comportamiento de las vigas en voladizo sometidas a cargas dinámicas, ya que disipan más energía que las elaboradas con concreto convencional, disminuyendo así el nivel de daños en estas.This study presents the effects of steel fiber reinforced concrete on the dynamic behavior of cantilever beams. In order to have a comparable base point for the experimental results, two conventional reinforced concrete specimens were made with the same materials and procedures than the steel fiber reinforced concrete elements, which are four, two with a ration of steel fibers of 15 kg/m3 and other two with 30 kg/m3. All specimens were subjected to pseudo-dynamic test from which it was possible to make comparisons about seismic hysteretic performance of different beams. Based on these results, it was found that the metal fibers improve the behavior of cantilever beams subjected to dynamic loads and dissipate more energy than that produced with conventional concrete, thus reducing the level of damage to these.Ingeniero (a) CivilPregrad

Pravastatin reduces plasma levels of extracellular vesicles in pregnancies at high risk of term preeclampsia

© 2023 Santoyo, Noguera, Avilés, Hernández-Caselles, de Paco-Matallana, Delgado, Cuevas, Llinás and Hernández..This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published Manuscript version of a Published Work that appearedin final form in Frontiers in Pharmacology. To access the final edited and published work see https://doi.org/10.3389/fphar.2023.116612

Oral vaccination with heat inactivated Mycobacterium bovis activates the complement system to protect against tuberculosis

Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model for mycobacterial infection and TB to characterize the protective mechanisms elicited by a new heat inactivated Mycobacterium bovis vaccine (IV). Oral vaccination with the IV resulted in significantly lower culture and lesion scores, particularly in the thorax, suggesting that the IV might provide a novel vaccine for TB control with special impact on the prevention of pulmonary disease, which is one of the limitations of current vaccines. Oral vaccination with the IV induced an adaptive antibody response and activation of the innate immune response including the complement component C3 and inflammasome. Mycobacterial DNA/RNA was not involved in inflammasome activation but increased C3 production by a still unknown mechanism. The results also suggested a protective mechanism mediated by the activation of IFN-γ producing CD8+ T cells by MHC I antigen presenting dendritic cells (DCs) in response to vaccination with the IV, without a clear role for Th1 CD4+ T cells. These results support a role for DCs in triggering the immune response to the IV through a mechanism similar to the phagocyte response to PAMPs with a central role for C3 in protection against mycobacterial infection. Higher C3 levels may allow increased opsonophagocytosis and effective bacterial clearance, while interfering with CR3-mediated opsonic and nonopsonic phagocytosis of mycobacteria, a process that could be enhanced by specific antibodies against mycobacterial proteins induced by vaccination with the IV. These results suggest that the IV acts through novel mechanisms to protect against TB in wild boar

pH Modulation of Efflux Pump Activity of Multi-Drug Resistant Escherichia coli: Protection During Its Passage and Eventual Colonization of the Colon

BACKGROUND:Resistance Nodulation Division (RND) efflux pumps of Escherichia coli extrude antibiotics and toxic substances before they reach their intended targets. Whereas these pumps obtain their energy directly from the proton motive force (PMF), ATP-Binding Cassette (ABC) transporters, which can also extrude antibiotics, obtain energy from the hydrolysis of ATP. Because E. coli must pass through two pH distinct environments of the gastrointestinal system of the host, it must be able to extrude toxic agents at very acidic and at near neutral pH (bile salts in duodenum and colon for example). The herein described study examines the effect of pH on the extrusion of ethidium bromide (EB). METHODOLOGY/PRINCIPAL FINDINGS:E. coli AG100 and its tetracycline induced progeny AG100(TET) that over-expresses the acrAB efflux pump were evaluated for their ability to extrude EB at pH 5 and 8, by our recently developed semi-automated fluorometric method. At pH 5 the organism extrudes EB without the need for metabolic energy (glucose), whereas at pH 8 extrusion of EB is dependent upon metabolic energy. Phe-Arg beta-naphtylamide (PAbetaN), a commonly assumed inhibitor of RND efflux pumps has no effect on the extrusion of EB as others claim. However, it does cause accumulation of EB. Competition between EB and PAbetaN was demonstrated and suggested that PAbetaN was preferentially extruded. A K(m) representing competition between PAbetaN and EB has been calculated. CONCLUSIONS/SIGNIFICANCE:The results suggest that E. coli has two general efflux systems (not to be confused with a distinct efflux pump) that are activated at low and high pH, respectively, and that the one at high pH is probably a putative ABC transporter coded by msbA, which has significant homology to the ABC transporter coded by efrAB of Enterococcus faecalis, an organism that faces similar challenges as it makes its way through the toxic intestinal system of the host

Actualidad y prospectiva de la investigación científica en el Centro Universitario Amecameca de la Universidad Autónoma del Estado de México

Con responsabilidad, se organizó un programa cuya finalidad fuera publicitar con transparencia dichos avances, a través de un esfuerzo de rendición de cuentas a la comunidad inmediata, la universitaria, y a la comunidad abierta, la sociedad que la principal referencia para tal efecto. El programa se concretiza a través del presente libro, conformado con una inspiración de investigación multidisciplinaria; sin embargo, para llegar a tal fin, el reto es realizar el proceso de búsqueda y generación de conocimiento transitando hacia la colaboración de los cuerpos académicos, que puedan construir nuevos conocimientos fortalecidos por la convergencia de diferentes campos del saber. En consecuencia, la primera etapa de esta estrategia es la publicidad de los trabajos investigativos ejercidos, para hacer un balance al día, pero también proyectar el futuro de cada campo y área del conocimiento. La organización explicativa está organizada por tres bloques representativos del quehacer en la generación de conocimiento del Centro Universitario, un primer bloque centra el interés en las humanidades, educación y sustentabilidad; el segundo bloque lo integra la reflexión científica sobre la construcción democrática, derechos humanos y equidad de género; en el tercer segmento se destina a la seguridad alimentaria, salud pública y sistemas agropecuarios. La actualidad de la investigación eleva la producción lograda y lo que en el momento se encuentra en construcción y los alcances que produce para la docencia, la investigación misma, y para la sociedad en general. La prospectiva es un área que todos los capítulos desarrollan con el propósito de delinear los alcances innovadores por andar en teoría, metodología e incluso en los saberes mismo