Accelerator studies of neutrino oscillations

The question of whether the neutrino has a non-vanishing mass plays acrucial role in particle physics. A massive neutrino would unambiguously reveal the existence of new physics beyond the Standard Model. In addition, it could have profound implications on astrophysics and cosmology, with effects on the evolution of the Universe. Experiments aiming at direct neutrino-mass measurements based on kinematics have not been able, so far, to measure the very small neutrino mass. Indirect measurements can be performed by exploiting reactions which may only occur for massive neutrinos. Neutrino oscillation is one of those processes. The mass difference between neutrino mass-eigenstates can be inferred from a phase measurement. This feature allows for high sensitivity experiments. Neutrinos from different sources can be used to search for oscillations: solar neutrinos, neutrinos produced in the interaction of cosmic rays with the atmosphere and artificially produced neutrinos from nuclear reactors and particle accelerators. The latter offer the possibility of choosing the relevant experimental features such as the flux flavour composition, the energy and the baseline distance from the source to the detector.This paper attempts to review the main accelerator experiments whichhave been performed and to outline the future projects. A brief introduction to the theory and phenomenology of neutrino oscillationsis given to help in understanding the scope, the design and the performance of the different experiments

Heavy quark studies with nuclear emulsions

Emulsions have started particle physics with the discovery of natural radioactivity by Becquerel in 1896. The development of the ``nuclear emulsions'' made it possible to detect tracks of single particle and to perform detailed measurements of their interactions. The discovery of the pion in 1947 was the first, spectacular demonstration of their unique features for the direct observation of the production and decay of short-lived particles, with negligible or very low background. In particular, these features are now exploited for studies of heavy quark physics in experiments where nuclear emulsions are combined with electronic detectors and profit is taken of the remarkable technological progress in automated analysis. In these experiments, neutrinos provide a selective probe for specific quark flavors. Interesting results on charm production and decay are expected in the very near future.Comment: To be published on the book for the eightieth birthday of Roberto Salmeron, World Scientifi

Absolute determination of D_s branching ratios and f_{D_s} extraction at a neutrino factory

A method for a direct measurement of the exclusive D_s branching ratios and of the decay constant f_{D_s} with a systematical error better than 5% is presented. The approach is based on the peculiar vertex topology of the anti-neutrino induced diffractive charm events. The statistical accuracy achievable with a neutrino factory is estimated

A search for Z' in muon neutrino associated charm production

In many extensions of the Standard Model the presence of an extra neutral boson, Z', is invoked. A precision study of weak neutral-current exchange processes involving only second generation fermions is still missing. We propose a search for Z' in muon neutrino associated charm production. This process only involves Z' couplings with fermions from the second generation. An experimental method is thoroughly described using an ideal detector. As an application, the accuracy reachable with present and future experiments has been estimated.Comment: 13 pages, 3 figures, late

Apoptotic gene expression in neuropathic pain

Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms. Neuropathic pain treatment is extremely difficult, as it is a very complex disease, involving several molecular pathways. Excitatory or inhibitory pathways controlling neuropathic pain development show altered gene expression, caused by peripheral nerve injury.
This study used several experimental pain models to demonstrate the occurrence of programmed cell death in the centers controlling pain induction and maintenance, such as spinal cord and pre-frontal cortex. We combined behavioural, molecular and morphological approaches to assess the involvement of bcl-2 gene family and caspases in neuropathic pain. Chronic constriction injury (CCI) and spared nerve injury (SNI) of rodent sciatic nerve induced the appearance of pain-like behaviours, such as hyperalgesia and allodynia. An early (2-3 days post-CCI) apoptosis appeared in the spinal cord neurons as the pro-apoptotic bax gene increased (320±19%). The incidence of apoptosis appeared to be limited to the first few days following nerve injury. Subsequently, increased expression of anti-apoptotic bcl-2 family genes may inhibit further neuron loss. SNI triggered apoptotic pathway and caspases activation in pre-frontal cortex 7, 14, and 21 days post-injury. Among the time-points analyzed, RT-PCR analysis showed increased expression of the bax/bcl-2 ratio (40±2%), bid (16±2%), caspase-1 (84±3%), caspase-8 (53±6%), caspase-9 (25±6%), caspase-12 (58±2%), TNF (32±2%) genes in the cortex by 7 days post-injury. Western blot analysis showed increased active Caspase-3 protein levels in the cortex at 3, 7, 14, and 21 post-surgery. This study shows that apoptotic genes could be an useful pharmacological target in neuropathic pain controlling.
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Use of ANTARES and IceCube data to constrain a single power-law neutrino flux

We perform the first statistical combined analysis of the diffuse neutrino flux observed by ANTARES (nine-year) and IceCube (six-year) by assuming a single astrophysical power-law flux. The combined analysis reduces by a few percent the best-fit values for the flux normalization and the spectral index. Both data samples show an excess in the same energy range (40--200 TeV), suggesting the presence of a second component. We perform a goodness-of-fit test to scrutinize the null assumption of a single power-law, scanning different values for the spectral index. The addition of the ANTARES data reduces the $p$-value by a factor 2$\div$3. In particular, a single power-law component in the neutrino flux with the spectral index deduced by the six-year up-going muon neutrinos of IceCube is disfavored with a $p$-value smaller than $10^{-2}$.Comment: 6 pages, 4 figures. Version published in AP

Dispersion characteristics of leaky waves on lossless and lossy slotlines

This paper deals with the dependence of the type of solution of the determinantal slotline dispersion equation on the location of the poles of its matrix elements. A number of possible solutions above the cut-off frequencies of particular surface waves is determined. Complete dispersion characteristics of the 1st and 2nd leaky wave on the lossless and lossy slotline as well as the main characteristics of the 1st up to the 4th leaky wave on the lossless slotline are presented