El activismo religioso conservador en Latinoamérica

Pertenece a la colección Religión, Género y Sexualidad / dirigida por Juan M. Vaggione ; v.3El libro reúne un conjunto de análisis que ponen en evidencia la heterogeneidad y la complejidad de las estrategias de influencia de la religión como uno de los principales sostenes de sistemas heteronormativos en nuestras sociedades contemporáneas. Tanto al nivel de los actores como de los discursos, las formas en que las religiones influencian las discusiones sobre políticas de sexualidad han adoptado diversas modalidades de actuación adaptándose a los momentos políticos. Así, los artículos que integran la compilación se dirigen a complejizar el rol de lo religioso en la política sexual contemporánea incluyendo en esta problematización distintos ejes de análisis y marcos teóricos. Haciendo foco en diferentes países de América Latina, con sus escenarios y problemas, los artículos abordan las variadas dimensiones del activismo religioso conservador en nuestra región

Modelling pulsed immunotherapy of tumour-immune interaction

We develop a mathematical model that describes the tumour-immune interaction and the effect on it of pulsed immunotherapy, based on the administration of adoptive cellular immunotherapy (ACI) combined with interleukin-2 (IL-2). The stability conditions for the tumour-free periodic solution are provided with different frequencies of ACI applications and IL-2 infusions. Furthermore, the effects of period, dosage and times of drug deliveries on the amplitudes of the tumour-free periodic solution were investigated. The most feasible immunotherapy strategy was determined by comparing immunotherapy with ACI treatment with or without IL-2. However, to investigate how to enhance the efficacy of chemotherapy (radiotherapy) and reduce its sideeffects, we developed a model involving periodic applications of immunotherapy with chemotherapy (radiotherapy) applied only when the density of the tumour reached a given threshold. The results revealed that the initial densities, the effector cell: tumour cell ratios, the periods T and a given critical number of tumour cells CT are crucial for cancer treatment, which confirms that it is important to customise treatment strategies for individual patients

Retrospective assessment of inguinal hernia repair in elderly outpatients

Background In the last ten years Day Surgery has significantly evolved, due to improvements in surgery and anaesthesia, and the need of reducing long term admission costs [1]. However, is Day Surgery suitable for elderly patients? The aim of this paper is to assess the risk of over 70 year-old outpatients who underwent inguinal hernia repair, and suggest an adequate preoperative pathway

A new internally heated diamond anvil cell system for time-resolved optical and x-ray measurements

We have developed a new internally heated diamond anvil cell (DAC) system for in situ high-pressure and high-temperature x-ray and optical experiments. We have adopted a self-heating W/Re gasket design allowing for both sample confinement and heating. This solution has been seldom used in the past but proved to be very efficient to reduce the size of the heating spot near the sample region, improving heating and cooling rates as compared to other resistive heating strategies. The system has been widely tested under high-temperature conditions by performing several thermal emission measurements. A robust relationship between electric power and average sample temperature inside the DAC has been established up to about 1500 K by a measurement campaign on different simple substances. A micro-Raman spectrometer was used for various in situ optical measurements and allowed us to map the temperature distribution of the sample. The distribution resulted to be uniform within the typical uncertainty of these measurements (5% at 1000 K). The high-temperature performances of the DAC were also verified in a series of XAS (x-ray absorption spectroscopy) experiments using both nano-polycrystalline and single-crystal diamond anvils. XAS measurements of germanium at 3.5 GPa were obtained in the 300 K-1300 K range, studying the melting transition and nucleation to the crystal phase. The achievable heating and cooling rates of the DAC were studied exploiting a XAS dispersive setup, collecting series of near-edge XAS spectra with sub-second time resolution. An original XAS-based dynamical temperature calibration procedure was developed and used to monitor the sample and diamond temperatures during the application of constant power cycles, indicating that heating and cooling rates in the 100 K/s range can be easily achieved using this device

Preface for CEEPE 2020 Proceedings

Journal of Physics: Conference Series, Volume 1585, 2020 the 3rd International Conference on Energy, Electrical and Power Engineering (CEEPE 2020) 24-26 April 2020, Chongqing, ChinaThe 3rd International Conference on Energy, Electrical, and Power Engineering (CEEPE) was planned to be held in April 24-26, 2020, in Chongqing, China, and was co-sponsored by the University of Electronic Science and Technology of China; Wuhan University, China; Shandong University, China; South Asia Institute of Science and Engineering (SAISE) and IEEE PES Chongqing Chapter. Due to the unexpected COVID 19 pandemic, that closed the world to national and international travel, the organization decided to hold the CEEPE 2020 totally online. It was a challenge, not only to the organizers, but also to the participants who were delivering their speeches using videoconference tools, under different time zones. This conference brought together researchers and engineers in academia and industry from China, Iraq, Japan and Portugal to discuss the latest developments and implementation, in these countries, of electrical power in applications ranging from commercial generation and distribution, to electric vehicles, with a particular focus on renewable energy integration in power systems, automation and control systems. Although there was not the opportunity to meet face-to-face under a live social environment, attendees from different areas of the world could interact under the videoconference tool, clarify their doubts and establish business and technical connections. The proceedings of these presentations are listed here in peer reviewed, written form.info:eu-repo/semantics/publishedVersio

Relevância do padrão de remodelamento ventricular no modelo de infarto do miocárdio em ratos

Background: The relevance of the remodeling pattern in the model of infarcted rats is not known. Objective: To analyze the presence of different patterns of remodeling in this model and its functional implications. Methods: Infarcted rats (n=47) have been divided according to the geometry pattern, analyzed by echocardiogram: normal (normal mass index and normal relative thickness), concentric remodeling (normal mass index and increased relative thickness), concentric hypertrophy (increased mass index and increased relative thickness) and eccentric hypertrophy (increased mass index and normal relative thickness). Data are median and interquartile range. Results: Infarcted rats showed only two of the four geometric patterns: normal pattern (15%) and eccentric hypertrophy - EH (85%). Groups of normal pattern and EH showed no differences in the values of fractional area change (Normal = 32.1-28.8 to 50.7; EH = 31.3-26.5 to 36.7; p = 0.343). Out of the infarcted animals, 34 (74%) had systolic dysfunction, detected by fractional area change. Considering these two geometry patterns, 77% of animals with eccentric hypertrophy and 57% with normal geometry presented systolic dysfunction (p=0.355). The relative wall thickness, the geometric patterns and the body mass index were not predictors of ventricular dysfunction (p>0.05). On the other hand, infarct size was a predictive factor for ventricular dysfunction in univariate analysis (p<0.001) and multivariate analysis (p = 0.004). Conclusion: Rats that underwent coronary occlusion showed two different patterns of remodeling, which do not constitute a predictor of ventricular dysfunction.Faculdade de Medicina de Botucatu, Botucatu, SPFaculdade de Medicina de Botucatu, Botucatu, S

Preditores ecocardiográficos de remodelação ventricular após o infarto agudo do miocárdio em ratos

Background: The prediction of the ventricular remodeling process after acute myocardial infarction (AMI) may have important clinical implications. Objetive: To analyze echocardiographic variables predictors of remodeling in the infarction model in rats. Methods: The animals underwent echocardiography in two moments, five days and three months after infarction (AMI group) or sham surgery (control group). Linear regression was used to identify the echocardiographic variables on the fifth day after the infarction, which were predictive of remodeling after three months of coronary occlusion. We considered as a criterion of remodeling in this study, the values of left ventricular diastolic diameter (LVDD) after three months of infarction. Results: The infarction induced increase in the left chambers, associated with changes in systolic and diastolic functions. The variables body weight, left ventricular wall stress index (LVWSI), systolic area (SA), diastolic area (DA), LVDD, left ventricular systolic diameter (LVSD), fractional area change (FAC), ejection fraction (EF), fractional shortening (%Short), posterior wall shortening velocity (PWSV) and infarct size assessed five days after infarction were predictors of LVDD after three months. At the multivariate regression analysis, we included the size of infarction, the LVWSI and PWSV. The LVWSI (coefficient: 4.402, standard error: 2.221, p = 0.05), but not the size of infarction and PWSV, was a predictor of remodeling after three months of infarction. Conclusion: LVPSI was an independent predictor of remodeling three months after the myocardial infarction and could be included in the clinical stratification after the coronary occlusion.Faculdade de Medicina de Botucatu, Botucatu, SPFaculdade de Medicina de Botucatu, Botucatu, S

The Role of Oxidative Stress and Lipid Peroxidation in Ventricular Remodeling Induced by Tobacco Smoke Exposure after Myocardial Infarction

OBJECTIVE: To evaluate the roles of oxidative stress and lipid peroxidation in the ventricular remodeling that is induced by tobacco smoke exposure after myocardial infarction.METHODS: After induced myocardial infarction, rats were allocated into two groups: C (control, n=25) and ETS (exposed to tobacco smoke, n=24). After 6 months, survivors were submitted to echocardiogram and biochemical analyses.RESULTS: Rats in the ETS group showed higher diastolic (C = 1.52 +/- 0.4 mm(2), ETS = 1.95 +/- 0.4 mm(2); p=0.032) and systolic (C = 1.03 +/- 0.3, ETS = 1.36 +/- 0.4 mm(2)/g; p=0.049) ventricular areas, adjusted for body weight. The fractional area change was smaller in the ETS group (C = 30.3 +/- 10.1 %, ETS = 19.2 +/- 11.1 %; p=0.024) and E/A ratios were higher in ETS animals (C = 2.3 +/- 2.2, ETS = 5.1 +/- 2.5; p=0.037). ETS was also associated with a higher water percentage in the lung (C = 4.8 (4.3-4.8), ETS = 5.5 (5.3-5.6); p=0.013) as well as higher cardiac levels of reduced glutathione (C = 20.7 +/- 7.6 nmol/mg of protein, ETS = 40.7 +/- 12.7 nmol/mg of protein; p=0.037) and oxidized glutathione (C = 0.3 +/- 0.1 nmol/g of protein, ETS = 0.9 +/- 0.3 nmol/g of protein; p=0.008). No differences were observed in lipid hydroperoxide levels (C = 0.4 +/- 0.2 nmol/mg of tissue, ETS = 0.1 +/- 0.1 nmol/mg of tissue; p=0.08).CONCLUSION: In animals exposed to tobacco smoke, oxidative stress is associated with the intensification of ventricular re-remodeling after myocardial infarction