712 research outputs found

    Culture’s Backlash on Decision Making

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    A questão colocada neste artigo é a de saber se as lições aprendidas em Srebrenica (Unprofor) conduziram a alteração de cultura nas relações civis-militares. Foi estudado o processo de tomada de decisão para demonstrar alteração de cultura. Foi o processo de tomada de decisão ao tempo da Unprofor que fez prova de um choque entre as culturas militares e civis. Depois de um inquérito parlamentar sobre Srebrenica, procedimentos de tomada de decisão considerando desenvolvimentos foram aperfeiçoados através da utilização de um conjunto de critérios chamados “Toetsingskader”. Os parlamentares usam estes critérios para questionar o governo sobre muitos assuntos importantes relativos a desenvolvimento. A aplicação dos critérios ao desenvolvimento na Etiópia e Eritreia foi bastante pacífica dado tratar-se de uma situação “clássica” de manutenção da paz de primeira geração. Os critérios contidos no “Toetsingskader” foram submetidos a uma prova mais severa no processo de tomada de decisão respeitante à participação na Força de Estabilização do Iraque (SFIR) em 2003. Por um lado, o “Toetsingskader” provou ser novamente instrumento útil para controlo parlamentar. Provou ser um instrumento capaz de preencher o fosso entre a cultura política, militar e civil. Por outro lado mantém- se o risco de raciocínio teleológico. Os critérios podem facilmente ser usados para justificar a participação pela racionalização dos objectivos de desenvolvimento e/ou ignorando questões críticas

    Evaluation of acoustic noise in magnetic resonance imaging

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    Magnetic resonance imaging (MRI) is a technique in which strong static and dynamic magnetic fields are used to create virtual slices of the human body. The process of MR imaging is associated with several health and safety issues which may negatively affect patient and radiological health workers. Potentially hazardous are biological effects of both the static and dynamic magnetic fields, the torques of the magnetic fields acting on ferromagnetic objects, thermal effects, and the negative effects of high acoustic sound pressures. The subject of this dissertation is the evaluation and modification of acoustic noise generated during MRI

    Interventional MR imaging at 1.5 T: quantification of sound exposure

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    Sound pressure levels (SPLs) during interventional magnetic resonance (MR) imaging may create an occupational hazard for the interventional radiologist (ie, the potential risk of hearing impairment). Therefore, A-weighted and linear continuous-equivalent SPLs were measured at the entrance of a 1.5-T MR imager during cardiovascular and real-time pulse sequences. The SPLs ranged from 81.5 to 99.3 dB (A-weighted scale), and frequencies were from 1 to 3 kHz. SPLs for the interventional radiologist exceeded a safe SPL of 80 dB (A-weighted scale) for all sequences; therefore, hearing protection is recommended

    Labelling of mammalian cells for visualisation by MRI

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    Through labelling of cells with magnetic contrast agents it is possible to follow the fate of transplanted cells in vivo with magnetic resonance imaging (MRI) as has been demonstrated in animal studies as well as in a clinical setting. A large variety of labelling strategies are available that allow for prolonged and sensitive detection of the labelled cells with MRI. The various protocols each harbour specific advantages and disadvantages. In choosing a particular labelling strategy it is also important to ascertain that the labelling procedure does not negatively influence cell functionality, for which a large variety of assays are available. In order to overcome the challenges still faced in fully exploiting the benefits of in vivo cell tracking by MRI a good understanding and standardisation of the procedures and assays used will be crucial

    Diagnostic performance of stress myocardial perfusion imaging for coronary artery disease: A systematic review and meta-analysis

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    Objectives To determine and compare the diagnostic performance of stress myocardial perfusion imaging (MPI) for the diagnosis of obstructive coronary artery disease (CAD), using conventional coronary angiography (CCA) as the reference standard. Methods We searched Medline and Embase for literature that evaluated stress MPI for the diagnosis of obstructive CAD using magnetic resonance imaging (MRI), contrastenhanced echocardiography (ECHO), single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Results All pooled analyses were based on random effects models. Articles on MRI yielded a total of 2,970 patients from 28 studies, articles on ECHO yielded a sample size of 795 from 10 studies, articles on SPECT yielded 1,323 from 13 studies. For CAD defined as either at least 50 %, at least 70 % or at least 75 % lumen diameter reduction on CCA, the natural logarithms of the diagnostic odds ratio (lnDOR) for MRI (3.63; 95 % CI 3.26-4.00) was significantly higher compared to that of SPECT (2.76; 95 % CI 2.28-3.25; P=0.006) and that of ECHO (2.83; 95 % CI 2.29-3.37; P=0.02). There was no significant difference between the lnDOR of SPECT and ECHO (P=0.52). Conclusion Our results suggest that MRI is superior for the diagnosis of obstructive CAD compared with ECHO and SPECT. ECHO and SPECT demonstrated similar diagnostic performance. Key Points ̇ MRI can assess myocardial perfusion. ̇ MR perfusion diagnoses coronary artery disease better than echocardiography or SPECT. ̇ Echocardiography and SPECT have similar diagnostic performance. ̇ MRI can save coronary artery disease patients from more invasive tests. ̇ MRI and SPECT show evidence of publication bias, implying possible overestimation

    Evaluation of a Semi-automatic Right Ventricle Segmentation Method on Short-Axis MR Images

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    The purpose of this study was to evaluate a semi-automatic right ventricle segmentation method on short-axis cardiac cine MR images which segment all right ventricle contours in a cardiac phase using one seed contour. Twenty-eight consecutive short-axis, four-chamber, and tricuspid valve view cardiac cine MRI examinations of healthy volunteers were used. Two independent observers performed the manual and automatic segmentations of the right ventricles. Analyses were based on the ventricular volume and ejection fraction of the right heart chamber. Reproducibility of the manual and semi-automatic segmentations was assessed using intra- and inter-observer variability. Validity of the semi-automatic segmentations was analyzed with reference to the manual segmentations. The inter- and intra-observer variability of manual segmentations were between 0.8 and 3.2%. The semi-automatic segmentations were highly correlated with the manual segmentations (R2 0.79–0.98), with median difference of 0.9–4.8% and of 3.3% for volume and ejection fraction parameters, respectively. In comparison to the manual segmentation, the semi-automatic segmentation produced contours with median dice metrics of 0.95 and 0.87 and median Hausdorff distance of 5.05 and 7.35 mm for contours at end-diastolic and end-systolic phases, respectively. The inter- and intra-observer variability of the semi-automatic segmentations were lower than observed in the manual segmentations. Both manual and semi-automatic segmentations performed better at the end-diastolic phase than at the end-systolic phase. The investigated semi-automatic segmentation method managed to produce a valid and reproducible alternative to manual right ventricle segmentation

    Antegrade balloon dilatation as a treatment option for posttransplant ureteral strictures: Case series of 50 patients

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    Objectives: The aim of this study was to investigate the effects of antegrade balloon dilatation on ureteral strictures that developed after kidney transplant. Materials and Methods: The hospital databases of the Erasmus Medical Center (Rotterdam, The Netherlands) and the Academic Medical Center (Amsterdam, The Netherlands) were retrospectively screened for patients who underwent balloon dilatation after kidney transplant. Balloon dilatation was technically successful whenever it was able to pass the strictured segment with the guidewire followed by balloon inflation; the procedure was clinically successful if no further interventions (for example, surgical revision of the ureteroneocystostomy or prolonged double J placement) were necessary. Results: Fifty patients (2.4%) of 2075 kidney transplant recipients underwent antegrade balloon dilatation because of urinary outflow obstruction. Median time between transplant and balloon dilatation was 3 months (range, 0-139 mo). In 43 patients (86%), balloon dilatation was technically successful. In the remaining 7 patients (14%), it was impossible to pass the strictured segment with the guidewire. In 20 of 43 patients (47%) having a technically successful procedure, the procedure was also clinically successful, with median follow-up after balloon dilatation of 35.5 months (range, 0-102 mo). We did not identify any patient o

    Continuous roadmapping in liver TACE procedures using 2D–3D catheter-based registration

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    PURPOSE: Fusion of pre/perioperative images and intra-operative images may add relevant information during image-guided procedures. In abdominal procedures, respiratory motion changes the position of organs, and thus accurate image guidance requires a continuous update of the spatial alignment of the (pre/perioperative) information with the organ position during the intervention. METHODS: In this paper, we propose a method to register in real time perioperative 3D rotational angiography images (3DRA) to intra-operative single-plane 2D fluoroscopic images for improved guidance in TACE interventions. The method uses the shape of 3D vessels extracted from the 3DRA and the 2D catheter shape extracted from fluoroscopy. First, the appropriate 3D vessel is selected from the complete vascular tree using a shape similarity metric. Subsequently, the catheter is registered to this vessel, and the 3DRA is visualized based on the registration results. The method is evaluated on simulated data and clinical data. RESULTS: The first selected vessel, ranked with the shape similarity metric, is used more than 39 % in the final registration and the second more than 21 %. The median of the closest corresponding points distance between 2D angiography vessels and projected 3D vessels is 4.7–5.4 mm when using the brute force optimizer and 5.2–6.6 mm when using the Powell optimizer. CONCLUSION: We present a catheter-based registration method to continuously fuse a 3DRA roadmap arterial tree onto 2D fluoroscopic images with an efficient shape similarity

    Percutaneous transhepatic biliary drainage in patients with postsurgical bile leakage and nondilated intrahepatic bile ducts

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    Objective and Background: Bile leakage is a serious postoperative complication and percutaneous transhepatic biliary drainage (PTBD) may be an option when endoscopic treatment is not feasible. In this retrospective study, we established technical and clinical success rates as well as the complication rates of PTBD in a large group of patients with postoperative bile leakage. Methods: Data on all patients with nondilated intrahepatic bile ducts who underwent a PTBD procedure for the treatment of bile leakage between January 2000 and August 2012 were retrospectively assessed. Data included type of surgery, site of bile leak, previous attempts of bile leak repair, interval between surgery and PTBD placement. Outcome measures were the technical and clinical success rates, the procedure-related complications, and mortality rate. Results: A total of 63 patients were identified; PTBD placement was technically successful in 90.5% (57/63) after one to three attempts. The clinical success rate was 69.8% (44/63). Four major complications were documented (4/63; 6.3%): liver laceration, pneumothorax, pleural empyema, and prolonged hemobilia. One minor complication involved pain. Conclusion
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