616 research outputs found
An Investigation of the Effect of Ventilation Inlet and Outlet Arrangement on Heat Concentration in a Ship Engine Room
Τhe ventilation in the ship engine rooms is an essential issue concerning finest performance of engines and diesel generators as well as electric motors. The present study has aimed at the analysis of temperature distribution inside the ship main engine room. In the same way, attempts have been made to identify those points with considerable thermal concentration in main engine room space, so that proper ventilation systems could be engineered and utilized and favorable thermal conditions could be realized. The CFD approach has been utilized in order to analyze impact of the designed ventilation system on the temperature distribution pattern. The Inlet layout and area have been analyzed under a variety of scenarios in order to decrease the average temperature and eliminate the heat concentrations in various points of the engine room. The temperature distribution and location and area of ventilation air inlet have been studied in different modes resulted in temperature distribution pattern, heat concentration outline and average volumetric temperature level in each mode. The results indicated that considerable circulating air volume is required compared to those levels suggested by common practices, calculations and standards in order to eliminate the heat concentration
Music distraction among young drivers: analysis by gender and experience
The aim of this study was to quantify the probability of committing a speed infraction by young drivers and to investigate to what extent listening music could affect young drivers’ emotions as well as their driving performances at the wheel. To achieve this aim, employing Bayesian networks, the study analysed different music styles, in which they resulted in sample drivers’ speed infractions. Gender and drivers’ experiences at the wheel were the other factors, which were taken into account when interpreting the study results. Variables taken into account in this study included type of music whilst driving, gender of drivers, and drivers’ driving experiences. These variables further incorporated into the study of other telemetric variables including acceleration, number of revolutions per minute (RPM) of the engine, brake, traffic, and other types of infractions other than speed, which were considered as dependent variables. A driving simulator was used, and different driving simulation studies were carried out with young people aged between 20 and 28 years. Each participant carried out three simulations by listening to different type of music in each journey. The study defined a conceptual model in which the data were analysed and evaluated mathematically through Bayesian networks. A sensitivity analysis was performed to evaluate the influence of music on driving speed. Based on the different variables, the study further analysed the probability of speed infractions committed by drivers and their adequate speed. The range of frequency probabilities varied between 96.32% (which corresponds to experienced male drivers who do not listen to music) and 79.38% (which corresponds to less-experienced female drivers who listen to music), which resulted in their happiness or aggression.FEDER (Fondo Europeo de Desarrollo Regional) for developing Castilla y Le´on´s region. *e title of the project is “Modelizaci´on mediante t´ecnicas de machine learning de la influencia de las distracciones del conductor en la seguridad vial-Modeling the influence of driver´s distractions on road safety through machine learning techniques.” Ref. BU300P1
Scotopic contrast sensitivity and glare after accelerated corneal cross-linking
Background: The aim was to assess one-year changes in uncorrected and corrected contrast sensitivity (CS) and glare under scotopic conditions after accelerated cross-linking (CXL) using the 18 mW/cm2 protocol for the treatment of progressive keratoconus and compare results with unoperated controls. Methods: In this non-randomised clinical trial, 30 eyes were enrolled in the CXL group and 30 were assigned to the control group. Scotopic CS at spatial frequencies (SFs) of 0.5, 1.1, 2.2, 3.4, 7.1 and 15 cycles per degree (cpd) were assessed using the MonCv3System (Metrovision, Pérenchies, France) under scotopic conditions (0.5 lux) at baseline and at six and 12 months. Results: The mean ages of the participants in the CXL and control groups were 24.32 ± 5.17 and 30.93 ± 7.43 years, respectively (p < 0.001). After adjusting for age, changes in uncorrected and corrected CS and glare were similar in the two groups (all p > 0.05) except for corrected CS at SF 7.1 cpd (1.45 ± 4.31 versus 3.21 ± 4.69 dB, p = 0.010) and 15 cpd (1.12 ± 4.63 versus 3.03 ± 5.48 dB, p = 0.007), which were reduced as an effect of CXL. Based on covariate analyses, among corrected CS indices, corrected CS7.1 and CS15 were related to CXL and their baseline values (all p < 0.050). Uncorrected CS in all SFs and uncorrected and corrected glare were related to their pre-operative values (all p < 0.001). Conclusion: Accelerated CXL can reduce scotopic corrected CS at SFs higher than 7.0 cpd in cases with better baseline values of these parameters. Changes in uncorrected CS and glare are only a factor of baseline values and the indices reduce in cases with better baseline values after one year. © 2017 Optometry Australi
Hyperglycemia decreased medial amygdala projections to medial Preoptic area in experimental model of diabetes mellitus
In Wistar rats, reproductive behavior is controlled in a neural circuit of ventral forebrain including the medial amygdala (Me), bed nucleus of the stria terminalis (BNST) and medial preoptic area (MPOA) via perception of social odors. Diabetes Mellitus (DM) is a widespread metabolic disease that affects many organs in a variety of levels. DM can cause central neuropathies such as neuronal apoptosis, dendritic atrophy, neurochemical alterations and also causes reproductive dysfunctions. So we hypothesized damage to the nuclei of this circuit can cause reproductive dysfunctions. Therefore in this project we assessed diabetic effect on these nuclei. For this purpose neuron tracing technique and TUNEL assay were used. We injected HRP in the MPOA and counted labeled cells in the Me and BNST to evaluate the reduction of neurons in diabetic animals. Also, coronal sections were analyzed with the TMB histochemistry method. Animals in this study were adult male Wistar rats (230 ± 8g) divided to control and 10-week streptozotocin-induced diabetic groups. After data analysis by SPSS 16 software, a significant reduction of HRP-labeled neurons was shown in both Me and BNST nuclei in the diabetic group. Moreover, apoptotic cells were significantly observed in diabetic animals in contrast to control the group. In conclusion, these alterations of the circuit as a result of diabetes might be one of the reasons for reproductive dysfunctions. © 2015 Tehran University of Medical Sciences. All rights reserved
Advanced analysis of PRVEP in anisometropic amblyopia
Introduction: to identify the pattern-reversal visual evoked potential (PRVEP) waveform descriptor by evaluating discrete wavelet transform (DWT) in order to optimize stimulus in the diagnosis of anisometropia amblyopia. Materials and Methods: The PRVEP testing was performed for 31 normal individuals and 35 patients with amblyopia. The stimuli were consisted of spatial frequencies of 1, 2, and 4 cycles per degree (cpd) and contrast levels of 100, 50, 25, and 5. The results were analyzed in the dimensions of time and time-frequency. DWT descriptor were extracted at level 7 (7P descriptor) for Haar, Daubechies 2, Daubechies 4, Symlet 5, Biorthogonal 3.5, Biorthogonal 4.4, and Coiflet 5 wavelets for 12 stimuli and compared between the two groups. The correlation between different spatial frequencies at the same contrast level and the similarities between reconstructed signals and original waveforms were evaluated. Results: There were a significant reduction in P100 amplitude and a significant elevation in latency among the patient group. In the patients with amblyopia, 7P descriptor decreased in all analysis except for the frequency of 4 cpd and the contrast of 5 using bior4.4. No significant correlation was observed between different frequencies at a special contrast; however, there was a significant correlation between reconstructed signals and the original ones. Conclusion: The 7P descriptor could be used to distinguish between normal and abnormal signals in anisometropia amblyopia. Considering the results, DWT with coif5, db4, bior4.4, and bior3.5 wavelets can be utilized as a good indicator for selecting optimum stimulus. © 2018, Mashhad University of Medical Sciences
Global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017
Background
Understanding the patterns of HIV/AIDS epidemics is crucial to tracking and monitoring the progress of prevention and control efforts in countries. We provide a comprehensive assessment of the levels and trends of HIV/AIDS incidence, prevalence, mortality, and coverage of antiretroviral therapy (ART) for 1980–2017 and forecast these estimates to 2030 for 195 countries and territories.
Methods
We determined a modelling strategy for each country on the basis of the availability and quality of data. For countries and territories with data from population-based seroprevalence surveys or antenatal care clinics, we estimated prevalence and incidence using an open-source version of the Estimation and Projection Package—a natural history model originally developed by the UNAIDS Reference Group on Estimates, Modelling, and Projections. For countries with cause-specific vital registration data, we corrected data for garbage coding (ie, deaths coded to an intermediate, immediate, or poorly defined cause) and HIV misclassification. We developed a process of cohort incidence bias adjustment to use information on survival and deaths recorded in vital registration to back-calculate HIV incidence. For countries without any representative data on HIV, we produced incidence estimates by pulling information from observed bias in the geographical region. We used a re-coded version of the Spectrum model (a cohort component model that uses rates of disease progression and HIV mortality on and off ART) to produce age-sex-specific incidence, prevalence, and mortality, and treatment coverage results for all countries, and forecast these measures to 2030 using Spectrum with inputs that were extended on the basis of past trends in treatment scale-up and new infections.
Findings
Global HIV mortality peaked in 2006 with 1·95 million deaths (95% uncertainty interval 1·87–2·04) and has since decreased to 0·95 million deaths (0·91–1·01) in 2017. New cases of HIV globally peaked in 1999 (3·16 million, 2·79–3·67) and since then have gradually decreased to 1·94 million (1·63–2·29) in 2017. These trends, along with ART scale-up, have globally resulted in increased prevalence, with 36·8 million (34·8–39·2) people living with HIV in 2017. Prevalence of HIV was highest in southern sub-Saharan Africa in 2017, and countries in the region had ART coverage ranging from 65·7% in Lesotho to 85·7% in eSwatini. Our forecasts showed that 54 countries will meet the UNAIDS target of 81% ART coverage by 2020 and 12 countries are on track to meet 90% ART coverage by 2030. Forecasted results estimate that few countries will meet the UNAIDS 2020 and 2030 mortality and incidence targets.
Interpretation
Despite progress in reducing HIV-related mortality over the past decade, slow decreases in incidence, combined with the current context of stagnated funding for related interventions, mean that many countries are not on track to reach the 2020 and 2030 global targets for reduction in incidence and mortality. With a growing population of people living with HIV, it will continue to be a major threat to public health for years to come. The pace of progress needs to be hastened by continuing to expand access to ART and increasing investments in proven HIV prevention initiatives that can be scaled up to have population-level impact
Smoking stages, prevalence of drug abuse and role of associated psychological and social factors: A study on male high school students in Ilam city
Background & Aims: There are limited information about prevalence of smoking, drug abuse and its associated factors amongst Iranian students. The present study aimed to determine prevalence of smoking and drug abuse amongst male high school students in Ilam and the role of associated psychological and social factors. Method: Overall, 1000 male high school students were recruited using a multi-stage sampling method. A self-administered questionnaire was used for data gathering. Chi-square test and logistic regression model were used for univariate, multivariate and interactions analyses. Results: Mean age of students was 16.2 years. The prevalence of experimenter and regular smokers were 11.4 (95 CI: 9.3 -13.4) and 1.3 (95 CI: 0.5-2.0) respectively. Prevalence rates of alcohol, opium, Tramadol, Hashish, Ecstasy and methamphetamine abuses were 11.1 (9.1-13.0), 2.8 (1.7-3.8), 7.6 (5.9-9.2), 3.3 (2.1-4.4), 2.7 (1.6-3.7), and 2.1 (1.1-3.0) respectively. The logistic regression model showed a significant relationship between having a smoker friend (AOR: 1.99), self-injury (AOR: 2.35), peer pressure (AOR: 2.37) and Tramadol abuse (AOR: 3.00) and different stages of smoking. None of the considered interactions had significant effect. Conclusions: Although, prevalence of smoking in Ilam high school students was less than the corresponding reports from other provinces in Iran, drugs abuse followed the same pattern as the other provinces. In addition, psychosocial variables had an important role in adolescents smoking
Total factor productivity change in broiler insurance: evidence from Iran
Abstract Insurance is one of the primary risk management tools in the agricultural sector. In Iran, the crop insurance fund operates as a quasi-government institution, and many agricultural insurance practices have remained traditional for years without necessary innovations. In 2016, managers of crop insurance fund decided to adopt a Negotiation-Oriented insurance approach for the first time in broiler industry. In this approach, all steps including the determination of insurance premiums were conducted through consultation and coordination with the broiler industry producers’ union, rather than being dictated by government directives. This research analyzes changes in total factor productivity of broiler insurance before and after the implementation of this new approach, using the Malmquist index and Data Envelopment Analysis (DEA). Data were collected from the Iran crop Insurance fund's Comprehensive System (CS) for the period of 2010-2020. The results indicate that after the implementation of the negotiation-oriented method, total factor productivity of insurance in the broiler industry improved by 19.7% annually during 2016-2020
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations
Investigation on Quality Properties of Traditional Bulk Bread Covered with Probiotics and Soybean Oil Edible Coating
Probiotic food products are available at the supermarket commercially, but probiotic bakery products are much less in evidence. In the present study, methyl cellulose (2%), whey protein concentrate (2%), corn starch (1%), and soybean oil at 2, 4, and 6% were used for coating layer on the bulked bread surface, and then the quality properties were studied. The results showed that Lactobacillus rhamnosus GG, as probiotic component of the coating, immobilized in corn starch, whey protein, and methyl cellulose films had enhanced viability throughout shelf-life. The probiotics remained viable for 4 days, maintaining high viable cell number levels. Adding soybean oil at 6% concentration enhanced texture, sensory properties, and image index during storage
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