96 research outputs found

    Prioritize the Dimensions of Knowledge Quality in Data Driven Organizations (Case Study: Iranian Research Institute for Information Science and Technology)

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    Objective: Knowledge is one of the most important competitive and value creating advantages of organizations, and for effective use of knowledge, attention should be paid to its quality. Data driven organizations rely on their data assets. Quality and reliable data in organizations leads to better decision making, and the knowledge quality in data driven organizations leads to growth and increase in profitability and innovation. The present research was conducted in order to investigate and prioritize the dimensions of knowledge quality in data driven organizations. Methods: The statistical population of this research is made up of 10 experts in this field in the Research Iranian Research Institute for Information Science and Technology (IranDoc). In order to collect data, while reviewing the literature on the subject, interviews with experts of Iranian Research Institute for Information Science and Technology and questionnaires were used. For data analysis, the fuzzy DEMATEL method was used to determine the relationships between indicators and the ANP method was used for weighting and prioritizing criteria. Results: The results of data analysis through questionnaires and solutions using EXCEL software show that among the main criteria, the representational knowledge quality is the highest quality priorities. Also, among the sub-criteria, the degree of Expandability with a weight of (0.15089) was the first priority, Understandability with a weight of (0.14039) was the second priority, and Interpretability was the third priority with a weight of (0.13687). Conclusions: It is observed that the sub-criterion of expandability and use of knowledge content in the future through knowledge sharing and integration has a much greater impact on the perceived quality of knowledge in data-oriented organizations than other sub-criteria

    A Study on the Explicit and Implicit Memory Bias among People with Social Anxiety Disorder and Normal Participants

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    Anxiety disorders, especially social phobia, are among the most important disorders among university students, which need particular attention. The present research was carried out to compare explicit and implicit memory among people with social phobia and normal subjects. In the present study which is of the causal-comparative type, the research subjects consisted of 50 individuals suffering from social anxiety disorder and 50 normal individuals, who were selected via screening from among the students of the University of Tabriz. Data collection was performed using the social anxiety scale, word stem completion task, and cued recall test. The collected data were analyzed using the multivariate analysis of variance method. The results of the study showed that there was a significant difference between the two groups in implicit memory when remembering positive and negative words, but no significant difference was observed between the two groups in explicit memory

    Application of Freire\u27s adult education model in modifying the psychological constructs of health belief model in self-medication behaviors of older adults: a randomized controlled trial.

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    BACKGROUND: Self-medication by older adults has been always a public health concern. The present study aimed to modify the psychological constructs of Health Belief Model (HBM) in relation to self-medication behaviors using Freire\u27s Adult Education Model (FAEM) among older adults in Khorramabad, Iran, from 2017 to 2018. METHODS: The mean age of the older adults was 66.28 ± 7.18 years. This was a randomized controlled trial study conducted on 132 individuals older than 60 who were referred from different health care centers. The participants were selected using multistage sampling method and randomly divided into two groups of intervention and control. The data collection instruments included a questionnaire which was designed based on both HBM and self-medication behaviors questionnaire. The phase of adult education model (AEM) was used to modify the psychological constructs of HBM and self-medication behaviors. Data were analyzed using SPSS software version 20 with a significant level of 0.05. Descriptive statistical tests, chi-squared test, paired t-test, independent t-test, and univariate modeling were employed for the purpose of analyzing data. RESULTS: There was no significant difference between groups in terms of self-medication. Unawareness of the effects of medicine were the most important reason for self-medication (p = 0.50). The two groups were not significantly different in terms of knowledge, HBM constructs, and self-medication behaviors (p \u3e 0.05). However, they came up to be considerably different for the above variables after the intervention was implemented (p \u3c  0.05). When the findings were adjusted for the effects of confounding variables, there were significant differences between the two groups in almost all constructs of HBM and their behaviors (p \u3c  0.05). However, the perceived barrier modality of HBM did not reach to a significant level of difference between two groups. CONCLUSION: The educational intervention, which was based on Freire\u27s AEM, had positive effects on the constructs of HBM and consequently on self-medication behaviors. The psychological constructs of HBM were affected at the phases of listening to problems. Self-medication was tempered at the action-reflection phase with shared creation and evaluation of the action plan geared toward the achievement of the behavioral objectives. The results might be of importance to healthcare professionals involved in care of older patients. TRIAL REGISTRATION: Current Controlled Trials IRCT2013091814512N2. Registered on January 2 - prospectively registered, the trial was registered in the Iranian Clinical Trials Registry http://www.irct.ir

    Interaction of viral oncogenic proteins with the Wnt signaling pathway

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    It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenesis. Different signaling pathways play a part in the carcinogenesis that occurs in a cell. Among these pathways, the Wnt signaling pathway plays a predominant role in carcinogenesis and is known as a central cellular pathway in the development of tumors. There are three Wnt signaling pathways that are well identified, including the canonical or Wnt/β-catenin dependent pathway, the noncanonical or β-catenin-independent planar cell polarity (PCP) pathway, and the noncanonical Wnt/Ca2+ pathway. Most of the oncogenic viruses modulate the canonical Wnt signaling pathway. This review discusses the interaction between proteins of several human oncogenic viruses with the Wnt signaling pathway

    Isothermal, Kinetic, and Thermodynamic Studies on the Adsorption of Molybdenum by a Nanostructured Magnetic Material

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    In this study, the magnetic 3-(trimethoxysilyl) propyl methacrylate (TMSPMA) – poly (4-vinylpyridine) (P4VP) was synthesized and characterized. Removal of Molybdenum (Mo) from aqueous solutions using prepared material as nanosorbent was investigated. The magnetic P4VP was prepared by copolymerization of P4VP with TMSPMA. The prepared adsorbent was characterized by various techniques including the X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). The batch adsorption technique was applied and the effect of several important parameters such as pH of the aqueous solution, adsorbent dose, initial Mo(VI) concentration, contact time, and temperature was evaluated. Desorption behavior of Mo(VI) and the effect of foreign ions (Cd2+, Ca2+, Co2+, Fe3+, Ba2+ and Pt4+) in real samples were also investigated. Co (II) and Pt (IV) had a greater impact on the adsorption process than other foreign ions. The maximum capacity for Mo(VI) adsorption on the prepared adsorbent was 4.87 mg/g, which was obtained at a temperature of 40°C with an initial concentration of 10 mg/L of Mo(VI). The adsorption isotherms were best fitted with the Weber Van Vliet isotherm model. The kinetic data were fitted well with the pseudo-second-order equation with a high correlation coefficient (R2 > 0.99). Based on the negative standard Gibbs free energy change (ΔG° 0), it was found that the adsorption was an endothermic and a spontaneous process in nature

    Fungal infection in cystic fibrosis

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    Background: The prevalence of fungal infections has been increasing in recent years. Cystic fibrosis (CF) is a genetic disorder that affects organs such as the intestines, liver, pancreas, and especially the lungs. Introduction: Fungal pathogens are becoming a challenge in CF. Advanced medical science is associated with longer life expectancy in some patient groups. Method: A review was conducted on studies found on such online databases as Google Scholar, PubMed, and Scopus. Internet-based searches were performed on these databases for cystic fibrosis, respiratory infections, and fungal infection profiling to identify all relevant studies published between 2010 and 2020. Result: Fungal pathogens most frequently isolated from the respiratory tract include the Aspergillus genus, the Candida genus, Scedosporium apiospermum, and the Rasamsonia genus. In cystic fibrosis, these organisms usually colonize the respiratory and intestinal tracts and cause hypersensitivity responses and invasive diseases. Conclusion: Fungus-patient interactions are complicated and depend on various factors. Moreover, the emergence of drug-resistant species is a serious health issue, and the development of new treatments is crucial. </jats:sec
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