Sensible energy accounting with abstract metering for multicore systems

Chip multicore processors (CMPs) are the preferred processing platform across different domains such as data centers, real-time systems, and mobile devices. In all those domains, energy is arguably the most expensive resource in a computing system. Accurately quantifying energy usage in a multicore environment presents a challenge as well as an opportunity for optimization. Standard metering approaches are not capable of delivering consistent results with shared resources, since the same task with the same inputs may have different energy consumption based on the mix of co-running tasks. However, it is reasonable for data-center operators to charge on the basis of estimated energy usage rather than time since energy is more correlated with their actual cost. This article introduces the concept of Sensible Energy Accounting (SEA). For a task running in a multicore system, SEA accurately estimates the energy the task would have consumed running in isolation with a given fraction of the CMP shared resources. We explain the potential benefits of SEA in different domains and describe two hardware techniques to implement it for a shared last-level cache and on-core resources in SMT processors. Moreover, with SEA, an energy-aware scheduler can find a highly efficient on-chip resource assignment, reducing by up to 39% the total processor energy for a 4-core system.Peer ReviewedPostprint (author's final draft

CITES, wild plants, and opportunities for crime

The illegal trade in endangered plants damages both the environment and local communities by threatening and destroying numerous species and important natural resources. There is very little research which systematically addresses this issue by identifying specific opportunities for crime. This article presents the results of an interdisciplinary study which brings together criminological and conservation science expertise to identify criminal opportunities in the illegal wild plant trade and suggest strategies in order to prevent and mitigate the problem. Methodologically, the study adapts a crime proofing of legislation approach to the UN Convention on the International Trade in Endangered Species of Wild Fauna and Flora and is based on documentary and interview data. Situational crime prevention is used as a framework to provide points for effective intervention

Avaliação de coberturas vegetais na cultura da mandioca (manihot esculenta crantz) em neossolos quartzarênicos distróficos.

O presente estudo teve o objetivo de avaliar a produção de raízes de mandioca e de matéria seca da aveia preta e do azevém em diferentes sistemas de cultivo. No presente trabalho, são apresentados somente os resultados de matéria seca das coberturas vegetais

DynAMO: Improving parallelism through dynamic placement of atomic memory operations

With increasing core counts in modern multi-core designs, the overhead of synchronization jeopardizes the scalability and efficiency of parallel applications. To mitigate these overheads, modern cache-coherent protocols offer support for Atomic Memory Operations (AMOs) that can be executed near-core (near) or remotely in the on-chip memory hierarchy (far). This paper evaluates current available static AMO execution policies implemented in multi-core Systems-on-Chip (SoC) designs, which select AMOs' execution placement (near or far) based on the cache block coherence state. We propose three static policies and show that the performance of static policies is application dependent. Moreover, we show that one of our proposed static policies outperforms currently available implementations. Furthermore, we propose DynAMO, a predictor that selects the best location to execute the AMOs. DynAMO identifies the different locality patterns to make informed decisions, improving AMO latency and increasing overall throughput. DynAMO outperforms the best-performing static policy and provides geometric mean speed-ups of 1.09× across all workloads and 1.31× on AMO-intensive applications with respect to executing all AMOs near.This research was supported by the Spanish Ministry of Science and Innovation (MCIN) through contracts [PID2019-107255GB-C21], [TED2021-132634A-I00], and [PID2019-105660RB-C21]; the Generalitat of Catalunya through contract [2021-SGR-00763]; the Government of Aragon [T5820R]; the Arm-BSC Center of Excellence, and the European Processor Initiative (EPI) which is part of the European Union’s Horizon 2020 research and innovation program under grant agreement No. 826647. V. Soria-Pardos has been supported through an FPU fellowship [FPU20-02132]; A. Armejach is a Serra Hunter Fellow and has been partially supported by the Grant [IJCI-2017-33945] funded by MCIN/AEI/10.13039/501100011033; M. Moreto through a Ramón y Cajal fellowship [RYC-2016-21104].Peer ReviewedPostprint (author's final draft

The postoperative venous thromboembolism (TREVO) study – risk and case mortality by surgical specialty

Introdução e objetivos: O tromboembolismo venoso, cujo risco está aumentado no doente cirúrgico, é uma causa evitável de morbimortalidade. O objetivo primário deste estudo foi estimar o risco de tromboembolismo venoso sintomático pós‐operatório global e por especialidade cirúrgica, num hospital terciário. Secundariamente, foram analisadas a gravidade e mortalidade dos eventos tromboembólicos. Métodos: Foi realizado um estudo retrospetivo para a identificação de casos de tromboembolismo venoso pós‐operatório intra‐hospitalar, codificados pela Classificação Internacional de Doenças – 9.ª revisão, pelos critérios da Joint Commission International. Foram incluídos episódios de internamento de doentes adultos, operados, no período 2008‐2012. Resultados: Em 67 635 episódios de internamento com cirurgia identificaram‐se 90 casos de tromboembolismo venoso pós‐operatório (mediana de idades: 59 anos), correspondendo a um risco de 1,33/1000 episódios (intervalo de confiança a 95% [IC95%], 1,1‐1,6/1000). A neurocirurgia apresentou maior risco (4,07/1000), seguida pela urologia e pela cirurgia geral p < 0,001. Houve 50 episódios de embolia pulmonar, dos quais 11 foram fatais. Dos 90 casos, 12,2% decorreram sob anestesia do neuro‐eixo e 55,1% em doentes em estado físico ASA III. Foi administrada dose profilática de anticoagulante injetável no pós‐operatório a, pelo menos, 37,7% dos doentes. O risco decresceu de 2008 até 2012. A mortalidade associada aos eventos de tromboembolismo venoso durante o internamento foi 21,1% (IC95%, 13,6‐30,4). Conclusões: O risco de tromboembolismo venoso sintomático pós‐operatório foi de 1,33/1000. A neurocirurgia apresentou maior risco. A mortalidade foi de 21,1%

Neuronal processes contain the essential components for the late steps of ribosome biogenesis

Neurons rely on spatial and temporal control of protein synthesis to respond rapidly and locally to external stimuli, a process facilitated by the dynamic localization and modification of ribosomes. While previous research has shown that neuronal activity can regulate ribosome localization and modify translation rates, little is known about ribosomal assembly within neuronal processes. Here, we investigated the potential for local ribosome maturation in rat neurons using proteomics, RNA sequencing, and imaging methods. We detected an abundance of ribosome biogenesis factors in distal neuronal compartments, particularly those associated with the late stages of ribosome assembly. Moreover, we detected cytosolic pre-ribosomal RNA species in dendrites, as well as the enzymes necessary for their processing, suggesting that local ribosome maturation can occur far from the nucleus. These findings challenge conventional models that confine ribosome biogenesis to nuclear and perinuclear regions and suggest that neurons may fine-tune local protein synthesis by regulating ribosome assembly near synaptic sites. This mechanism may enable rapid modulation of the translational capacity in response to physiological changes, regulating synaptic plasticity and local protein synthesis in neurons

Neuronal processes contain the essential components for the late steps of ribosome biogenesis

Neurons rely on spatial and temporal control of protein synthesis to respond rapidly and locally to external stimuli, a process facilitated by the dynamic localization and modification of ribosomes. While previous research has shown that neuronal activity can regulate ribosome localization and modify translation rates, little is known about ribosomal assembly within neuronal processes. Here, we investigated the potential for local ribosome maturation in rat neurons using proteomics, RNA sequencing, and imaging methods. We detected an abundance of ribosome biogenesis factors in distal neuronal compartments, particularly those associated with the late stages of ribosome assembly. Moreover, we detected cytosolic pre-ribosomal RNA species in dendrites, as well as the enzymes necessary for their processing, suggesting that local ribosome maturation can occur far from the nucleus. These findings challenge conventional models that confine ribosome biogenesis to nuclear and perinuclear regions and suggest that neurons may fine-tune local protein synthesis by regulating ribosome assembly near synaptic sites. This mechanism may enable rapid modulation of the translational capacity in response to physiological changes, regulating synaptic plasticity and local protein synthesis in neurons

Perdas de solo em três diferentes sistemas de cultivo de mandioca (Manihot esculenta Crantz).

A mandioca (Manihot esculenta Crantz) é uma planta que possui pequena área foliar e lenta formação de copa, produz pouco resíduo cultural, exige amplo espaçamento entre linhas e no seu cultivo e colheita são comuns grandes movimentações de solo. Assim, pouco protege os solos dos efeitos erosivos das chuvas (OTSUBO et al., 2005). Margolis et al. (1991), estudaram diferentes sistemas de cultivos para mandioca num solo Podzólico Vermelho-Amarelo com 12% de declive e determinaram perdas anuais de solo variando entre 1,4 e 49,3 t/ha. [...]

Estimação dos componentes da variância fenotípica em feijoeiro utilizando o método genealógico.

A obtenção de informações a respeito do controle genético dos caracteres por meio de variâncias com associação aos métodos de condução de populações de feijoeiro tem sido uma estratégia pouco empregada, porém pode ser de grande auxílio aos melhoristas na tomada de decisões. Com esse objetivo foi utilizada uma população segregante proveniente do cruzamento entre as cultivares BRS MG Talismã e BRS Valente. O avanço das gerações foi realizado de acordo com o preconizado pelo método genealógico. Em F4:5 obtiveram-se 256 progênies que foram avaliadas na safra das águas 2004/2005. As sementes de cada progênie foram colhidas em bulk originando as progênies F4:6, as quais foram avaliadas na safra das secas 2005. Os caracteres avaliados foram produtividade de grãos e porte das plantas. Constatou-se que na produção de grãos por planta, a variância ambiental dentro da parcela foi o principal componente da variância fenotípica entre progênies. A variância genética aditiva foi predominante para a produção de grãos, enquanto que para o porte a variância genética de dominância foi expressiva