Trace geochemistry of lunar material

The lunar samples from the Apollo 16 and 17 flights which were analyzed include soil, igneous rock, anorthositic gabbro, orange soil, subfloor basalt, and norite breccia. Up to 57 elements including majors, minors, rare earths and other trace elements were determined in the lunar samples. The analytical techniques used were spark source mass spectrometry and neutron activation analysis. The latter was done either instrumentally or with group radiochemical separations. The differences in abundances of the elements in lunar soils at the various sites are discussed. With regard to the major elements only Si is about the same at all the sites. A detailed analysis which was performed on a sample of the Allende meteorite is summarized

Comparing legislative mechanisms for SEA screening and decision-making: Austrian and Australian experiences

Austrian and Australian approaches to strategic environmental assessment (SEA) are compared with particular emphasis upon the legal basis for the initial phase of agreement/screening and the final stage of SEA decision-making and implementation. In Austrian SEA, screening is compulsory and the outcome leads only to recommendations, meaning that the SEA results have to be considered, but are not binding for the approval decision. In Australia engagement in SEA is largely voluntary but the process results in legally binding conditions of approval that can be applied to relevant actions arising from an assessed policy, plan or programme; the incentive for proponents to participate voluntarily is that subsequent project level activities may be exempt from further assessment processes. Compulsory SEA in Australia also provides a legally certain outcome, a factor of benefit to proponents. Examples of SEAs are provided to demonstrate the operation of the respective stages in the two countries. In Austria compulsory screening results in a lot of energy being spent avoiding triggering a full SEA. Although Australian proponents have been somewhat cautious in volunteering for SEA of their activities, there are signs that this is changing. We argue that the regulatory framework characteristics are a key determinant of the behaviour of proponents and the competent authority in practice and subsequently of SEA potential and outcomes. Consideration of the construct of the regulatory framework for SEA screening and decision-making provides a useful point of reflection for practitioners attempting to understand the effectiveness of SEA processes in a given jurisdiction

A hybrid layout algorithm for sub-quadratic multidimensional scaling

Many clustering and layout techniques have been used for structuring and visualising complex data. This paper is inspired by a number of such contemporary techniques and presents a novel hybrid approach based upon stochastic sampling, interpolation and spring models. We use Chalmers' 1996 O(N/sup 2/) spring model as a benchmark when evaluating our technique, comparing layout quality and run times using data sets of synthetic and real data. Our algorithm runs in O(N/spl radic/N) and executes significantly faster than Chalmers' 1996 algorithm, whilst producing superior layouts. In reducing complexity and run time, we allow the visualisation of data sets of previously infeasible size. Our results indicate that our method is a solid foundation for interactive and visual exploration of data

The Habitability of our Evolving Galaxy

The notion of a Galactic Habitable Zone (GHZ), or regions of the Milky Way galaxy that preferentially maintain the conditions to sustain complex life, has recently gained attention due to the detection of numerous exoplanets and advances made in understanding habitability on the Earth and other environments. We discuss what a habitable environment means on large spatial and temporal scales, which necessarily requires an approximated definition of habitability to make an assessment of the astrophysical conditions that may sustain complex life. We discuss a few key exoplanet findings that directly relate to estimating the distribution of Earth-size planets in the Milky Way. With a broad notion of habitability defined and major observable properties of the Milky Way described, we compare selected literature on the GHZ and postulate why the models yield differing predictions of the most habitable regions at the present day, which include: (1) the majority of the galactic disk; (2) an annular ring between 7-9 kpc, and (3) the galactic outskirts. We briefly discuss the habitability of other galaxies as influenced by these studies. We note that the dangers to biospheres in the Galaxy taken into account in these studies may be incomplete and we discuss the possible role of Gamma-Ray Bursts and other dangers to life in the Milky Way. We speculate how changing astrophysical properties may affect the GHZ over time, including before the Earth formed, and describe how new observations and other related research may fit into the bigger picture of the habitability of the Galaxy.Comment: Chapter in Habitability of the Universe Before Earth, R. Gordon and A. Sharov (Eds.), Elsevie

Coordinating views for data visualisation and algorithmic profiling

A number of researchers have designed visualisation systems that consist of multiple components, through which data and interaction commands flow. Such multistage (hybrid) models can be used to reduce algorithmic complexity, and to open up intermediate stages of algorithms for inspection and steering. In this paper, we present work on aiding the developer and the user of such algorithms through the application of interactive visualisation techniques. We present a set of tools designed to profile the performance of other visualisation components, and provide further functionality for the exploration of high dimensional data sets. Case studies are provided, illustrating the application of the profiling modules to a number of data sets. Through this work we are exploring ways in which techniques traditionally used to prepare for visualisation runs, and to retrospectively analyse them, can find new uses within the context of a multi-component visualisation system

Molecular epidemiology of African sleeping sickness

Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give rise to epidemics followed by periods of endemicity A key to unravelling this puzzle is a detailed knowledge of the aetiological agents responsible for different patterns of disease--knowledge that is difficult to achieve using traditional microscopy. The science of molecular epidemiology has developed a range of tools which have enabled us to accurately identify taxonomic groups at all levels (species, subspecies, populations, strains and isolates). Using these tools, we can now investigate the genetic interactions within and between populations of Trypanosoma brucei and gain an understanding of the distinction between human- and nonhuman-infective subspecies. In this review, we discuss the development of these tools, their advantages and disadvantages and describe how they have been used to understand parasite genetic diversity, the origin of epidemics, the role of reservoir hosts and the population structure. Using the specific case of T.b. rhodesiense in Uganda, we illustrate how molecular epidemiology has enabled us to construct a more detailed understanding of the origins, generation and dynamics of sleeping sickness epidemics

Familial Ménière's disease: clinical and genetic aspects

ABSTRACT Background and purpose:Mre's disease is not uncommon, with an incidence in Caucasians of about one in 2000. The incidence peaks in the fifth decade. Cases are usually isolated or sporadic, but in perhaps five per cent other family members are affected. We report here the clinical and genetic characteristics of a comprehensive set of familial Mre's disease cases from the UK.Methods:Forty-six affected families were studied. All cases were diagnosed using the American Academy of Otolaryngolog 8211;Head and Neck Surgery committee on hearing and equilibrium 1995, or more stringent, criteria.Outcomes and results:Autosomal dominant inheritance with reduced penetrance was the most likely mode of inheritance overall. Apparent genetic anticipation was observed, but may also be a result of ascertainment bias given the collection strategy. There was also a slight tendency for cases to result from maternal transmission within the families in this set. The family pedigrees are presented, and the authors have also set up a website at which all the pedigrees may be viewed in greater detai