Supercurrent-phase relationship of a Nb/InAs(2DES)/Nb Josephson junction in overlapping geometry

Superconductor/normal conductor/superconductor (SNS) Josephson junctions with highly transparent interfaces are predicted to show significant deviations from sinusoidal supercurrent-phase relationships (CPR) at low temperatures. We investigate experimentally the CPR of a ballistic Nb/InAs(2DES)/Nb junction in the temperature range from 1.3 K to 9 K using a modified Rifkin-Deaver method. The CPR is obtained from the inductance of the phase-biased junction. Transport measurements complement the investigation. At low temperatures, substantial deviations of the CPR from conventional tunnel-junction behavior have been observed. A theoretical model yielding good agreement to the data is presented.Comment: RevTex4, 4 pages including 3 figure

Photonic band structure of highly deformable, self-assembling systems

We calculate the photonic band structure at normal incidence of highly deformable, self-assembling systems - cholesteric elastomers subjected to external stress. Cholesterics display brilliant reflection and lasing owing to gaps in their photonic band structure. The band structure of cholesteric elastomers varies sensitively with strain, showing new gaps opening up and shifting in frequency. A novel prediction of a total band gap is made, and is expected to occur in the vicinity of the previously observed de Vries bandgap, which is only for one polarisation

Cobot Programming for Collaborative Industrial Tasks: An Overview

Collaborative robots (cobots) have been increasingly adopted in industries to facilitate human-robot collaboration. Despite this, it is challenging to program cobots for collaborative industrial tasks as the programming has two distinct elements that are difficult to implement: (1) an intuitive element to ensure that the operations of a cobot can be composed or altered dynamically by an operator, and (2) a human-aware element to support cobots in producing flexible and adaptive behaviours dependent on human partners. In this area, some research works have been carried out recently, but there is a lack of a systematic summary on the subject. In this paper, an overview of collaborative industrial scenarios and programming requirements for cobots to implement effective collaboration is given. Then, detailed reviews on cobot programming, which are categorised into communication, optimisation, and learning, are conducted. Additionally, a significant gap between cobot programming implemented in industry and in research is identified, and research that works towards bridging this gap is pinpointed. Finally, the future directions of cobots for industrial collaborative scenarios are outlined, including potential points of extension and improvement

A systematic review and meta-synthesis of the impact of low back pain on people's lives

Copyright @ 2014 Froud et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.Background - Low back pain (LBP) is a common and costly problem that many interpret within a biopsychosocial model. There is renewed concern that core-sets of outcome measures do not capture what is important. To inform debate about the coverage of back pain outcome measure core-sets, and to suggest areas worthy of exploration within healthcare consultations, we have synthesised the qualitative literature on the impact of low back pain on people’s lives. Methods - Two reviewers searched CINAHL, Embase, PsycINFO, PEDro, and Medline, identifying qualitative studies of people’s experiences of non-specific LBP. Abstracted data were thematic coded and synthesised using a meta-ethnographic, and a meta-narrative approach. Results - We included 49 papers describing 42 studies. Patients are concerned with engagement in meaningful activities; but they also want to be believed and have their experiences and identity, as someone ‘doing battle’ with pain, validated. Patients seek diagnosis, treatment, and cure, but also reassurance of the absence of pathology. Some struggle to meet social expectations and obligations. When these are achieved, the credibility of their pain/disability claims can be jeopardised. Others withdraw, fearful of disapproval, or unable or unwilling to accommodate social demands. Patients generally seek to regain their pre-pain levels of health, and physical and emotional stability. After time, this can be perceived to become unrealistic and some adjust their expectations accordingly. Conclusions - The social component of the biopsychosocial model is not well represented in current core-sets of outcome measures. Clinicians should appreciate that the broader impact of low back pain includes social factors; this may be crucial to improving patients’ experiences of health care. Researchers should consider social factors to help develop a portfolio of more relevant outcome measures.Arthritis Research U

Effective Rheology of Bubbles Moving in a Capillary Tube

We calculate the average volumetric flux versus pressure drop of bubbles moving in a single capillary tube with varying diameter, finding a square-root relation from mapping the flow equations onto that of a driven overdamped pendulum. The calculation is based on a derivation of the equation of motion of a bubble train from considering the capillary forces and the entropy production associated with the viscous flow. We also calculate the configurational probability of the positions of the bubbles.Comment: 4 pages, 1 figur

Місце адміністративної юстиції в системі права України

Стаття присвячена питанням місця норм, що регулюють порядок діяльності адміністративних судів в Україні, у національній системі права. Окрему увагу приділено проблемі існування адміністративного процесуального права та варіантам йог існування.Статья посвящена вопросам места норм, регулирующих порядок деятельности административных судов в Украине, в национальной системе права. Отдельное внимание уделено проблеме существования административного процессуального права и вариантам его существования.Article is devoted to substantiation of the place of norms, regulating the order of activity of administrative courts in Ukraine in the national system of law. Separate attention is given to the problem of existence of administrative process law and variants of it's existence

Discrete-time volatility forecasting with persistent leverage effect and the link with continuous-time volatility modeling

We first propose a reduced-form model in discrete time for S&P 500 volatility showing that the forecasting performance can be significantly improved by introducing a persistent leverage effect with a long-range dependence similar to that of volatility itself. We also find a strongly significant positive impact of lagged jumps on volatility, which however is absorbed more quickly. We then estimate continuous-time stochastic volatility models that are able to reproduce the statistical features captured by the discrete-time model. We show that a single-factor model driven by a fractional Brownian motion is unable to reproduce the volatility dynamics observed in the data, while a multifactor Markovian model fully replicates the persistence of both volatility and leverage effect. The impact of jumps can be associated with a common jump component in price and volatility

Pressure during decision making of continuous sedation in end-of-life situations in Dutch general practice

<p>Abstract</p> <p>Background</p> <p>Little is known about pressure from patients or relatives on physician’s decision making of continuous palliative sedation. We aim to describe experienced pressure by general practitioners (GPs) in cases of continuous sedation after the introduction of the Dutch practice guideline, using a questionnaire survey.</p> <p>Methods</p> <p>A sample of 918 Dutch GPs were invited to fill out a questionnaire about their last patient under continuous sedation. Cases in which GPs experienced pressure from the patient, relatives or other persons were compared to those without pressure.</p> <p>Results</p> <p>399 of 918 invite GPs (43%) returned the questionnaire and 250 provided detailed information about their most recent case of continuous sedation. Forty-one GPs (16%) indicated to have experienced pressure from the patient, relatives or colleagues. In GPs younger than 50, guideline knowledge was not related to experienced pressure, whereas in older GPs, 15% with and 36% without guideline knowledge reported pressure. GPs experienced pressure more often when patients had psychological symptoms (compared to physical symptoms only) and when patients had a longer estimated life expectancy. A euthanasia request of the patient coincided with a higher prevalence of pressure for GPs without, but not for GPs with previous experience with euthanasia. GPs who experienced pressure had consulted a palliative consultation team more often than GPs who did not experience pressure.</p> <p>Conclusion</p> <p>One in six GPs felt pressure from patients or relatives to start sedation. This pressure was related to guideline knowledge, especially in older GPs, longer life expectancy and the presence of a euthanasia request, especially for GPs without previous experience of euthanasia.</p

A note on comonotonicity and positivity of the control components of decoupled quadratic FBSDE

In this small note we are concerned with the solution of Forward-Backward Stochastic Differential Equations (FBSDE) with drivers that grow quadratically in the control component (quadratic growth FBSDE or qgFBSDE). The main theorem is a comparison result that allows comparing componentwise the signs of the control processes of two different qgFBSDE. As a byproduct one obtains conditions that allow establishing the positivity of the control process.Comment: accepted for publicatio

Cancer immunoprevention and public health

The power of cancer immune surveillance has been documented beyond doubt, and the successful exploitation of immune response to cancer has started a new era in the war against cancer. Cancer biologists have recognized immunoevasion as an emerging hallmark in addition to the six hallmarks of cancer. Besides the natural connection between the immune system and cancer development, most established environmental risk factors are now known to interfere with immune surveillance mechanisms. Genetic variations regulating immunity may also modulate cancer susceptibility, but evidence for this is currently limited. Molecular cross talk linking “immune” and “genomic” surveillance pathways has been characterized. It appears that immune mechanisms may contribute to the effects of common cancer risk factors. We provide an updated overview of evidence for cancer immune surveillance, cancer risk factors interfering with it, and interventions to enhance cancer immune surveillance as tools to complement ongoing vaccine development efforts for cancer immunoprevention. Although there is a lot of support for cancer immunoprevention with simple lifestyle modifications from observational studies, there is an urgent need for clinical trials to establish the effectiveness of this approach for public health benefits