Reversing Paralysis Technology - Remarkable Breakthrough for the Treatment of Incurable Paralysis

This research has been developedto study on the Brain Computer Interface (BCI)technology - which is called a Reversing ParalysissTechnology. It is a momentous innovation ofmedical sector for the treatment of IncurableParalysis. The purpose of this study was to providea high level of evidences of the effectiveness andthe safety of this technology. The methodology ofthis study is using a qualitative systematic reviewmethod. It was followed by data collection andspecific keywords based data searching method.Two renowned research papers indexing databasehave been employed for locating peer reviewedscientific papers such as Pub-Med Database andGoogle Scholar Database. Besides this databasesearching, the Google Search also performed forcollecting scientific review news and informationsregarding this technology. Researchers analysedall keyword based from the selected literatures,from the clinical trial results and from the newsources; and then summarizes the findings inrespect of this technology. In this technology,the scientists have hypothesized that reversingof the paralyzed state of a patient is possible bycreating Brain Computer Interfaces (BCIs) in thepatient’s body through two brain implants. Oneimplant is placed on the surface of the brain orattached to the brain's cortex. Then, another oneis implanted in the spinal cord by passing theinjured lesion of spine. These two implants willact as a bridge between the command center (thebrain) and the control center (the spine). When theregular communication is established betweenthe brain and the spine, then the paralyzedcondition will reverse. The researchers, till to thisdate have analysed thirty seven (37) peer reviewedliteratures, twelve (12) scientific/tech based newsreview sources and four (4) authentic clinical trialresults which had been published in this context.Scientists claimed that this theory is effective andis safe for the treatment of paralysis based onsuccessful clinical trials. Thus, from this extensivequalitative systematic review study, it establisheda theory that Reversing Paralysis Technology isworking through Brain Computer Interfaces -Implants mechanism; and it is an effective and asafe process for patients’ paralysis treatment

OUTCOMES OF SURGICAL MANAGEMENT OF FRACTURE PENIS: EXPERIENCE FROM A TERTIARY CARE HOSPITAL IN BANGLADESH

Background: Penile fracture is an emergency and uncommon presentation to the urology department. Immediate surgical repair can be a standard of care for patients with penile fracture. Objective: The study was conducted to evaluate the outcome of surgical repair of the fractured penis. Methods: This quasi-experimental study was conducted from Jan 2017 to Dec 2018 in the urology department of Dhaka Medical College Hospital, Bangladesh. Thirty-five patients with fractures of the penis were included in this study. After proper evaluation, surgery was performed under spinal anesthesia. Follow up was scheduled at 6th week, 3rd month, and 6th month. We used validated questionnaires of the ‘International index of erectile function (IIEF-5)' for married and ‘Single question self-report (SQSR)' for unmarried patients to evaluate postoperative erectile function. Results: Total 35 patients completed three follow up. The mean age of patients was 36.4 years, and 88% of them were married. The most common triggers were for vigorous sexual intercourse (68.5%) followed by history of rolling over in bed with erect penis (20.0%). Per-operative findings were: rupture of tunica albuginea (100%); rupture of corpora cavernosa on the right (65.7%). After 6th month, 28 patients (80%) were able to maintain their normal erectile function. However, seven patients developed erectile dysfunction, of which 4 had a mild form, and 3 had mild to moderate form erectile dysfunction. All patients complained of pain during or after intercourse, but the pain has gradually subsided with time. Conclusion: Immediate surgical exploration and repair of fracture penis can offer complete recovery of sexual and voiding functions

Clinical Spectrum and Management of Diabetic Ketoacidosis: Experience in A Tertiary Care Hospital

Abstract Background: Diabetic ketoacidosis (DKA) is an acute metabolic complication of diabetes mellitus (DM). It may be the presenting feature in type 1 DM, but more commonly it complicates previously diagnosed diabetic patients, both type 1 and type 2. If not recognized early and treated in a judicious way the outcome is often fatal

ENTERIC MYOCARDITIS: A CASE REPORT

Enteric fever commonly causes fatality from abdominal complications or toxemia but it can also cause death from complications of myocarditis albeit rarely. In September, 2005 a 22 year old man was admitted in BIRDEM with the features of pneumonia. Later on, the patient developed acute left ventricular failure and ultimately diagnosed as a case of drug resistant enteric fever with myocarditis Ibrahim Med. Coll. J. 2007; 1(1): 34-3

Co-existence of Systemic Lupus Erythematosus and Autoimmune Hypothyroidism

Abstract not Available&#x0D; Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 1-2</jats:p

Extensively Drug-Resistant (XDR) Tuberculosis: A Review

Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any fluoroquinolone, and at least one of three injectable secondline drugs (amikacin, capreomycin, or kanamycin). This definition in immensely valuable for more uniform surveillance in varied international settings. The prevalence of tuberculosis drug resistance has risen to the highest rate ever recorded. Although the gold standard for drugsusceptibility testing has been the agar proportion method; due to it’s time consumption, more sensitive, specific and rapid diagnostic tests are required. It is difficult to differentiate XDR tuberculosis from non-XDR tuberculosis clinically, although the former is associated with greater morbidity and mortality. The treatment of XDR tuberculosis should include agents to which the organism is susceptible, and should continue for a minimum of 18-24 months. However, treatment continues to be limited in tuberculosisendemic countries largely because of weaknesses in national tuberculosis health-care models. The ultimate strategy to control drug-resistant tuberculosis is one that implements a comprehensive approach incorporating innovation from the political, social, economic, and scientific realms. DOI: http://dx.doi.org/10.3329/birdem.v1i1.12386 Birdem Med J 2011; 1(1): 30-36</jats:p

LD Bodies From Blood Buffy Coat: an Easy Approach for Definitive Diagnosis of Visceral Leishmaniasis

This observational study was carried out as a preliminary one to see the effectiveness and reliability of an easy noninvasive approach for the confirmatory diagnosis of Visceral Leishmaniasis (VL) by detection of amastigote forms (LD bodies) of the parasite. Clinically suspected 73 febrile cases were investigated by examination of bone marrow/splenic aspirate to detect LD bodies, of whom 57 (41.61%) showed LD positive result on microscopy and/or culture in modified Novy, Nichole, MacNeal (NNN) medium. Blood buffy coat was obtained by the method of density gradient centrifugation using mono-nuclear cell separation fluid "Lymphoprep" from all the cases confirmed as VL. Thin smears on microscopic slides were prepared from all 57 buffy coats, and stained by Leishman stain to see LD bodies microscopically. Out of 57 buffy coat smears, 53 (92.98%) yielded LD bodies. Findings of the present study has encouraged to carry out a field trial so that this easy approach can be practiced as a clinical diagnostic procedure.Bangladesh J Med Microbiol 2007; 01 (02): 43-47</jats:p

Emerging Antimicrobial Resistance amongst Common Bacterial Pathogens in Mymensingh Medical College Hospital

Antimicrobial resistance has been coming up as one of the challenging business for treating domiciliary and nosocomial infections. The present study compared rate of resistance towards different commonly used antibiotics for common bacterial pathogens isolated during 2001 to 2003. Regarding Escherichia coli, mentionable increase (p&lt;0.01) of resistance was noted against ceftazidime (47% to 77%) and ceftriaxone (43% to 71%). Imipenem (2% to 1%) and pefloxacin (40% to 17%) showed decreased trend. For Staphylococcus aureus, marked increase in resistance was shown against almost all antibiotics except co-trimoxazole (55% to 57%). Mentionable increase in resistance (p&lt;0.05 and p&lt;0.001, respectively) was noted against ciprofloxacin (17% to 43%) and ceftriaxone (28% to 83%). Although, oxacillin resistance increased from 22% to 42% but no resistance against vancomycin was noted during this period. Strains  of  Pseudomonas  species  showed  increase  (p&lt;0.05)  in  resistance  against  ciprofloxacin  (47%  to  71%), ceftriaxone (50% to 74%) and ceftazidime (39% to 58%). Carbenicillin showed decreased resistance (92% to 50%) and none of the strains was found resistant to imipenem. Emphasis was given towards judicial use of antibiotics by followig local antibiogram.Bangladesh J Med Microbiol 2007; 01 (01): 04-09</jats:p