Design and Development of RF Structures for Linac4

Linac4 is a new 160 MeV Hâ linac proposed at CERN to replace the 50 MeV Linac2 as injector to the PS Booster, with the goal of doubling its brightness and intensity. The present design foresees after RFQ and chopping line a sequence of three accelerating structures: a Drift Tube Linac (DTL) from 3 to 40 MeV, a Cell-Coupled DTL (CCDTL) to 90 MeV and a Side Coupled Linac (SCL) up to the final energy. The DTL and CCDTL operate at 352 MHz, while in the SCL the frequency is doubled to 704 MHz. Although the injection in the PS Booster requires only a low duty cycle, the accelerating structures are designed to operate at the high duty cycle required by a possible future extension to a high-power linac driver for a neutrino facility. This paper presents the different accelerating structures, underlining the progress in the design of critical resonator elements, like post-couplers in the DTL, coupling slots in the CCDTL and bridge couplers for the SCL. Prototyping progress for the different structures is reported, including the RF design of a DTL tank prototype and results of low- and high-power tests on a CCDTL prototype

RF Structures for Linac4

Linac4 is proposed to replace the existing proton linac at CERN (Linac2). Using an increased injection energy of 160 MeV instead of 50 MeV, Linac4 is expected to double the beam intensity in the PS Booster (PSB) and will thus be the first step towards higher brightness beams in the LHC. In this paper we re-assess the choice of RF structures for Linac4. Different accelerating structures for different energy ranges are compared in terms of RF efficiency, ease of construction and alignment, and necessary infrastructure. Eventually we present the final choice for Linac4

Bactericidal activity of biosynthesized silver nanoparticles against human pathogenic bacteria

Green synthesis is an attractive and eco-friendly approach to generate potent antibacterial silver nanoparticles (Ag-NPs). Such particles have long been used to fight bacteria and represent a promising tool to overcome the emergence of antibiotic-resistant bacteria. In this study, green synthesis of Ag-NPs was attempted using plant extracts of Aloe vera, Portulaca oleracea and Cynodon dactylon. The identity and size of Ag-NPs was characterized by ultraviolet–visible spectrophotometer and scanning electron microscopy. Monodispersed Ag-NPs were produced with a range of different sizes based on the plant extract used. The bactericidal activity of Ag-NPs against a number of human pathogenic bacteria was determined using the disc diffusion method. The results showed that Gram positive bacteria were more susceptible than Gram negative ones to these antibacterial agents. The minimum inhibitory concentration was determined using the 96-well plate method. Finally, the mechanism by which Ag-NPs affect bacteria was investigated by SEM analysis. Bacteria treated with Ag-NPs were seen to undergo shrinkage and to lose their viability. This study provides evidence for a cheap and effective method for synthesizing potent bactericidal Ag-NPs and demonstrates their effectiveness against human pathogenic bacteria

Corporate Social Responsibility and Corporate Performance: Does Financial Reporting Quality Matter?

This study aims to analyze the role of social responsibility in times of crisis, where the study examines whether the role of social responsibility in the corporate performance will depend on its interaction with other basic aspects of the corporate business environment. In the contemporary economic context, information environment considers important aspects of the business environment, therefore, it can be suggested that the impact of social responsibility on the company’s performance will be clearer when considering its interaction with financial reporting quality. To test this argument, data from the Saudi business environment for the year 2020 was collected to explore the relationship between social responsibility and the company’s financial performance during the Corona pandemic, and the role of the financial reporting quality in that relationship. The results were largely consistent with the general argument of the study, the results showed that social responsibility does not affect the financial performance, but the interaction between it and the financial reporting quality positively affects the financial performance of the company during the pandemic period. Therefore, financial reporting quality play a major role in the extent to which social responsibility affects performance. The results represent a motivation for the various parties in the business environment to pay attention to the general framework of the companys business aspects when analyzing performance

Molecular identification of adenoviruses associated with respiratory infection in Egypt from 2003 to 2010.

BACKGROUND: Human adenoviruses of species B, C, and E (HAdV-B, -C, -E) are frequent causative agents of acute respiratory infections worldwide. As part of a surveillance program aimed at identifying the etiology of influenza-like illness (ILI) in Egypt, we characterized 105 adenovirus isolates from clinical samples collected between 2003 and 2010. METHODS: Identification of the isolates as HAdV was accomplished by an immunofluorescence assay (IFA) and confirmed by a set of species and type specific polymerase chain reactions (PCR). RESULTS: Of the 105 isolates, 42% were identified as belonging to HAdV-B, 60% as HAdV-C, and 1% as HAdV-E. We identified a total of six co-infections by PCR, of which five were HAdV-B/HAdV-C co-infections, and one was a co-infection of two HAdV-C types: HAdV-5/HAdV-6. Molecular typing by PCR enabled the identification of eight genotypes of human adenoviruses; HAdV-3 (n = 22), HAdV-7 (n = 14), HAdV-11 (n = 8), HAdV-1 (n = 22), HAdV-2 (20), HAdV-5 (n = 15), HAdV-6 (n = 3) and HAdV-4 (n = 1). The most abundant species in the characterized collection of isolates was HAdV-C, which is concordant with existing data for worldwide epidemiology of HAdV respiratory infections. CONCLUSIONS: We identified three species, HAdV-B, -C and -E, among patients with ILI over the course of 7 years in Egypt, with at least eight diverse types circulating

Agent-based modeling and simulation to assess flood preparedness and recovery of manufacturing small and medium-sized enterprises

Severe flooding has caused major damage and disruption to households, communities, businesses, and organizations in many parts of the world. In the United Kingdom (UK), flooding has been responsible for significant losses to the economy due to its impact on businesses, 99.9% of which are Small and Medium-sized Enterprises (SMEs). This paper reports on how agent-based modeling and simulation has been developed and used to assess the effectiveness of a range of physical/structural and social preparedness adaptation measures that can be implemented by manufacturing SMEs to reduce the impact of and expedite recovery from a major flood event. Results indicate the effectiveness of combinations of these adaptation measures in relation to a one in 1000 year flood event that has been modeled and simulated in a key industrial area of the UK which, in addition to having experienced severe flooding, has a high concentration of SMEs